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Q9Z8U5

- 6PGL_CHLPN

UniProt

Q9Z8U5 - 6PGL_CHLPN

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Protein

6-phosphogluconolactonase

Gene
pgl, devB, CPn_0239, CP_0523, CPj0239, CpB0245
Organism
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

Catalytic activityi

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.

Pathwayi

GO - Molecular functioni

  1. 6-phosphogluconolactonase activity Source: UniProtKB-EC

GO - Biological processi

  1. pentose-phosphate shunt Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciCPNE115711:GI7B-541-MONOMER.
CPNE115713:GHEY-249-MONOMER.
CPNE138677:GH8N-246-MONOMER.
CPNE182082:GH4N-253-MONOMER.
UniPathwayiUPA00115; UER00409.

Names & Taxonomyi

Protein namesi
Recommended name:
6-phosphogluconolactonase (EC:3.1.1.31)
Short name:
6PGL
Gene namesi
Name:pgl
Synonyms:devB
Ordered Locus Names:CPn_0239, CP_0523, CPj0239, CpB0245
OrganismiChlamydia pneumoniae (Chlamydophila pneumoniae)
Taxonomic identifieri83558 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
ProteomesiUP000000424: Chromosome, UP000000583: Chromosome, UP000000801: Chromosome, UP000000802: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 2582586-phosphogluconolactonasePRO_0000090092Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi115713.CPn0239.

Structurei

3D structure databases

ProteinModelPortaliQ9Z8U5.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0363.
HOGENOMiHOG000256282.
KOiK01057.
OMAiELTACVP.
OrthoDBiEOG63FW46.

Family and domain databases

InterProiIPR005900. 6-phosphogluconolactonase_DevB.
IPR006148. Glc/Gal-6P_isomerase.
[Graphical view]
PfamiPF01182. Glucosamine_iso. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01198. pgl. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9Z8U5-1 [UniParc]FASTAAdd to Basket

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MATLINFNDT NKLLLTKQPS LFIDLASKDW IASANQAIKQ RGAFYVALSG    50
GKTPLEIYKD IVINKDKLID PSKIFLFWGD ERLAPITSSE SNYGQAMSIL 100
RDLNIPDEQI FRMETENPDG AKKYQELIEN KIPDASFDMI MLGLGEDGHT 150
LSLFSNTSAL EEENDLVVFN SVPHLETERM TLTFPCVHKG KHVVVYVQGE 200
NKKPILKSVF FSEGREEKLY PIERVGRDRS PLFWIISPES YDIADFDNIS 250
SIYKMDIL 258
Length:258
Mass (Da):29,334
Last modified:May 1, 1999 - v1
Checksum:iE49CA50014ECB797
GO

Sequence cautioni

The sequence AAF73681.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
The sequence AAP98178.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
The sequence BAA98449.1 differs from that shown. Reason: Erroneous termination at position 42. Translated as Gly.

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti46 – 461V → G in BAA98449. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE001363 Genomic DNA. Translation: AAD18392.1.
AE002161 Genomic DNA. Translation: AAF73681.1. Different initiation.
BA000008 Genomic DNA. Translation: BAA98449.1. Sequence problems.
AE009440 Genomic DNA. Translation: AAP98178.1. Different initiation.
PIRiD72103.
G86520.
RefSeqiNP_224448.1. NC_000922.1.
NP_300298.1. NC_002491.1.
NP_445067.1. NC_002179.2.
NP_876521.1. NC_005043.1.

Genome annotation databases

EnsemblBacteriaiAAD18392; AAD18392; CPn_0239.
AAF73681; AAF73681; CP_0523.
AAP98178; AAP98178; CpB0245.
BAA98449; BAA98449; BAA98449.
GeneIDi1466928.
895149.
918768.
962735.
KEGGicpa:CP0523.
cpj:CPj0239.
cpn:CPn0239.
cpt:CpB0245.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE001363 Genomic DNA. Translation: AAD18392.1 .
AE002161 Genomic DNA. Translation: AAF73681.1 . Different initiation.
BA000008 Genomic DNA. Translation: BAA98449.1 . Sequence problems.
AE009440 Genomic DNA. Translation: AAP98178.1 . Different initiation.
PIRi D72103.
G86520.
RefSeqi NP_224448.1. NC_000922.1.
NP_300298.1. NC_002491.1.
NP_445067.1. NC_002179.2.
NP_876521.1. NC_005043.1.

3D structure databases

ProteinModelPortali Q9Z8U5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 115713.CPn0239.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAD18392 ; AAD18392 ; CPn_0239 .
AAF73681 ; AAF73681 ; CP_0523 .
AAP98178 ; AAP98178 ; CpB0245 .
BAA98449 ; BAA98449 ; BAA98449 .
GeneIDi 1466928.
895149.
918768.
962735.
KEGGi cpa:CP0523.
cpj:CPj0239.
cpn:CPn0239.
cpt:CpB0245.

Phylogenomic databases

eggNOGi COG0363.
HOGENOMi HOG000256282.
KOi K01057.
OMAi ELTACVP.
OrthoDBi EOG63FW46.

Enzyme and pathway databases

UniPathwayi UPA00115 ; UER00409 .
BioCyci CPNE115711:GI7B-541-MONOMER.
CPNE115713:GHEY-249-MONOMER.
CPNE138677:GH8N-246-MONOMER.
CPNE182082:GH4N-253-MONOMER.

Family and domain databases

InterProi IPR005900. 6-phosphogluconolactonase_DevB.
IPR006148. Glc/Gal-6P_isomerase.
[Graphical view ]
Pfami PF01182. Glucosamine_iso. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR01198. pgl. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CWL029.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AR39.
  3. "Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA."
    Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K., Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.
    Nucleic Acids Res. 28:2311-2314(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: J138.
  4. "The genome sequence of Chlamydia pneumoniae TW183 and comparison with other Chlamydia strains based on whole genome sequence analysis."
    Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P., Schneider S., Pohl T., Essig A., Marre R., Melchers K.
    Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TW-183.

Entry informationi

Entry namei6PGL_CHLPN
AccessioniPrimary (citable) accession number: Q9Z8U5
Secondary accession number(s): Q9JSH4, Q9K256
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: May 14, 2014
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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