Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

6-phosphogluconolactonase

Gene

pgl

Organism
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

Catalytic activityi

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.

Pathwayi

GO - Molecular functioni

  1. 6-phosphogluconolactonase activity Source: UniProtKB-EC

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
  2. pentose-phosphate shunt Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciCPNE115711:GI7B-541-MONOMER.
CPNE115713:GHEY-249-MONOMER.
CPNE138677:GH8N-246-MONOMER.
CPNE182082:GH4N-253-MONOMER.
UniPathwayiUPA00115; UER00409.

Names & Taxonomyi

Protein namesi
Recommended name:
6-phosphogluconolactonase (EC:3.1.1.31)
Short name:
6PGL
Gene namesi
Name:pgl
Synonyms:devB
Ordered Locus Names:CPn_0239, CP_0523, CPj0239, CpB0245
OrganismiChlamydia pneumoniae (Chlamydophila pneumoniae)
Taxonomic identifieri83558 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
ProteomesiUP000000802 Componenti: Chromosome UP000000583 Componenti: Chromosome UP000000801 Componenti: Chromosome UP000000424 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 2582586-phosphogluconolactonasePRO_0000090092Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi115713.CPn0239.

Structurei

3D structure databases

ProteinModelPortaliQ9Z8U5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0363.
HOGENOMiHOG000256282.
KOiK01057.
OMAiLFPGQTN.
OrthoDBiEOG63FW46.

Family and domain databases

InterProiIPR005900. 6-phosphogluconolactonase_DevB.
IPR006148. Glc/Gal-6P_isomerase.
[Graphical view]
PfamiPF01182. Glucosamine_iso. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01198. pgl. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9Z8U5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATLINFNDT NKLLLTKQPS LFIDLASKDW IASANQAIKQ RGAFYVALSG
60 70 80 90 100
GKTPLEIYKD IVINKDKLID PSKIFLFWGD ERLAPITSSE SNYGQAMSIL
110 120 130 140 150
RDLNIPDEQI FRMETENPDG AKKYQELIEN KIPDASFDMI MLGLGEDGHT
160 170 180 190 200
LSLFSNTSAL EEENDLVVFN SVPHLETERM TLTFPCVHKG KHVVVYVQGE
210 220 230 240 250
NKKPILKSVF FSEGREEKLY PIERVGRDRS PLFWIISPES YDIADFDNIS

SIYKMDIL
Length:258
Mass (Da):29,334
Last modified:May 1, 1999 - v1
Checksum:iE49CA50014ECB797
GO

Sequence cautioni

The sequence AAF73681.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence AAP98178.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence BAA98449.1 differs from that shown. Reason: Erroneous termination at position 42. Translated as Gly.Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti46 – 461V → G in BAA98449 (PubMed:10871362).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001363 Genomic DNA. Translation: AAD18392.1.
AE002161 Genomic DNA. Translation: AAF73681.1. Different initiation.
BA000008 Genomic DNA. Translation: BAA98449.1. Sequence problems.
AE009440 Genomic DNA. Translation: AAP98178.1. Different initiation.
PIRiD72103.
G86520.
RefSeqiNP_224448.1. NC_000922.1.
NP_300298.1. NC_002491.1.
NP_445067.1. NC_002179.2.
NP_876521.1. NC_005043.1.

Genome annotation databases

EnsemblBacteriaiAAD18392; AAD18392; CPn_0239.
AAF73681; AAF73681; CP_0523.
AAP98178; AAP98178; CpB0245.
BAA98449; BAA98449; BAA98449.
GeneIDi895149.
962735.
KEGGicpa:CP0523.
cpj:CPj0239.
cpn:CPn0239.
cpt:CpB0245.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001363 Genomic DNA. Translation: AAD18392.1.
AE002161 Genomic DNA. Translation: AAF73681.1. Different initiation.
BA000008 Genomic DNA. Translation: BAA98449.1. Sequence problems.
AE009440 Genomic DNA. Translation: AAP98178.1. Different initiation.
PIRiD72103.
G86520.
RefSeqiNP_224448.1. NC_000922.1.
NP_300298.1. NC_002491.1.
NP_445067.1. NC_002179.2.
NP_876521.1. NC_005043.1.

3D structure databases

ProteinModelPortaliQ9Z8U5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi115713.CPn0239.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD18392; AAD18392; CPn_0239.
AAF73681; AAF73681; CP_0523.
AAP98178; AAP98178; CpB0245.
BAA98449; BAA98449; BAA98449.
GeneIDi895149.
962735.
KEGGicpa:CP0523.
cpj:CPj0239.
cpn:CPn0239.
cpt:CpB0245.

Phylogenomic databases

eggNOGiCOG0363.
HOGENOMiHOG000256282.
KOiK01057.
OMAiLFPGQTN.
OrthoDBiEOG63FW46.

Enzyme and pathway databases

UniPathwayiUPA00115; UER00409.
BioCyciCPNE115711:GI7B-541-MONOMER.
CPNE115713:GHEY-249-MONOMER.
CPNE138677:GH8N-246-MONOMER.
CPNE182082:GH4N-253-MONOMER.

Family and domain databases

InterProiIPR005900. 6-phosphogluconolactonase_DevB.
IPR006148. Glc/Gal-6P_isomerase.
[Graphical view]
PfamiPF01182. Glucosamine_iso. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01198. pgl. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CWL029.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AR39.
  3. "Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA."
    Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K., Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.
    Nucleic Acids Res. 28:2311-2314(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: J138.
  4. "The genome sequence of Chlamydia pneumoniae TW183 and comparison with other Chlamydia strains based on whole genome sequence analysis."
    Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P., Schneider S., Pohl T., Essig A., Marre R., Melchers K.
    Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TW-183.

Entry informationi

Entry namei6PGL_CHLPN
AccessioniPrimary (citable) accession number: Q9Z8U5
Secondary accession number(s): Q9JSH4, Q9K256
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: April 1, 2015
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.