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Q9Z8Q7 (ALF1_CHLPN) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable fructose-bisphosphate aldolase class 1

EC=4.1.2.13
Alternative name(s):
Probable fructose-bisphosphate aldolase class I
Short name=FBP aldolase
Gene names
Name:fbaB
Ordered Locus Names:CPn_0281, CP_0477, CpB0289
OrganismChlamydia pneumoniae (Chlamydophila pneumoniae) [Complete proteome] [HAMAP]
Taxonomic identifier83558 [NCBI]
Taxonomic lineageBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia

Protein attributes

Sequence length349 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.

Subcellular location

Cytoplasm Probable.

Sequence similarities

Belongs to the DeoC/FbaB aldolase family. FbaB subfamily.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandSchiff base
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionfructose-bisphosphate aldolase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 349349Probable fructose-bisphosphate aldolase class 1
PRO_0000138942

Sites

Active site2371Schiff-base intermediate with dihydroxyacetone-P By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9Z8Q7 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: 69882529D685C7D9

FASTA34938,028
        10         20         30         40         50         60 
MLNIHDILGN DDENLLSYQC KHITKDKLTL PSHDFVDKVF GLSDRNNRVL RSLQTMFSHG 

        70         80         90        100        110        120 
RLANSGYLSI LPVDQGIEHS AGASFAINPI YFDPENIVKL AIESGCSAVA STYGTLSLLS 

       130        140        150        160        170        180 
RKYAHKIPFM LKLNHNELLS YPTKYHQIFF TQVEAAYSMG AVAVGATVYF GSETSNEEIV 

       190        200        210        220        230        240 
AVSNAFAKAR SLGLATVLWC YLRNPAFVAN GVDYHTAADL TGQADHLGAT LGADIVKQKL 

       250        260        270        280        290        300 
PTCQGGFKAI NFGKTDERVY SELSSNHPID LCRYQVLNSY CGKVGLINSG GPSGKNDFTE 

       310        320        330        340 
AARTAVINKR AGGMGLILGR KAFQRPLSEG IQLLNLVQDI YLDPNITIA 

« Hide

References

[1]"Comparative genomes of Chlamydia pneumoniae and C. trachomatis."
Kalman S., Mitchell W.P., Marathe R., Lammel C.J., Fan J., Hyman R.W., Olinger L., Grimwood J., Davis R.W., Stephens R.S.
Nat. Genet. 21:385-389(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CWL029.
[2]"Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39."
Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O., Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S., Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J., Gwinn M.L. expand/collapse author list , Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G., Salzberg S.L., Eisen J.A., Fraser C.M.
Nucleic Acids Res. 28:1397-1406(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AR39.
[3]"Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA."
Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K., Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.
Nucleic Acids Res. 28:2311-2314(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: J138.
[4]"The genome sequence of Chlamydia pneumoniae TW183 and comparison with other Chlamydia strains based on whole genome sequence analysis."
Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P., Schneider S., Pohl T., Essig A., Marre R., Melchers K.
Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: TW-183.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE001363 Genomic DNA. Translation: AAD18430.1.
AE002161 Genomic DNA. Translation: AAF38310.1.
BA000008 Genomic DNA. Translation: BAA98491.1.
AE009440 Genomic DNA. Translation: AAP98222.1.
PIRA86526.
C72097.
RefSeqNP_224486.1. NC_000922.1.
NP_300340.1. NC_002491.1.
NP_445024.1. NC_002179.2.
NP_876565.1. NC_005043.1.

3D structure databases

ProteinModelPortalQ9Z8Q7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING115713.CPn0281.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAD18430; AAD18430; CPn_0281.
AAF38310; AAF38310; CP_0477.
AAP98222; AAP98222; CpB0289.
BAA98491; BAA98491; BAA98491.
GeneID1466972.
894851.
919064.
963038.
KEGGcpa:CP0477.
cpj:CPj0281.
cpn:CPn0281.
cpt:CpB0289.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1830.
HOGENOMHOG000224791.
KOK11645.
OMAGIEHTAG.
OrthoDBEOG6JQGZX.

Enzyme and pathway databases

BioCycCPNE115711:GI7B-492-MONOMER.
CPNE115713:GHEY-295-MONOMER.
CPNE138677:GH8N-292-MONOMER.
CPNE182082:GH4N-301-MONOMER.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
InterProIPR013785. Aldolase_TIM.
IPR002915. DeoC/FbaB/lacD_aldolase.
[Graphical view]
PfamPF01791. DeoC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameALF1_CHLPN
AccessionPrimary (citable) accession number: Q9Z8Q7
Secondary accession number(s): Q9JQ77
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: June 11, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families