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Q9Z8Q7

- ALF1_CHLPN

UniProt

Q9Z8Q7 - ALF1_CHLPN

Protein

Probable fructose-bisphosphate aldolase class 1

Gene

fbaB

Organism
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 83 (01 Oct 2014)
      Sequence version 1 (01 May 1999)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei237 – 2371Schiff-base intermediate with dihydroxyacetone-PBy similarity

    GO - Molecular functioni

    1. fructose-bisphosphate aldolase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Lyase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    Schiff base

    Enzyme and pathway databases

    BioCyciCPNE115711:GI7B-492-MONOMER.
    CPNE115713:GHEY-295-MONOMER.
    CPNE138677:GH8N-292-MONOMER.
    CPNE182082:GH4N-301-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable fructose-bisphosphate aldolase class 1 (EC:4.1.2.13)
    Alternative name(s):
    Probable fructose-bisphosphate aldolase class I
    Short name:
    FBP aldolase
    Gene namesi
    Name:fbaB
    Ordered Locus Names:CPn_0281, CP_0477, CpB0289
    OrganismiChlamydia pneumoniae (Chlamydophila pneumoniae)
    Taxonomic identifieri83558 [NCBI]
    Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
    ProteomesiUP000000424: Chromosome, UP000000583: Chromosome, UP000000801: Chromosome, UP000000802: Chromosome

    Subcellular locationi

    Cytoplasm Curated

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 349349Probable fructose-bisphosphate aldolase class 1PRO_0000138942Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi115713.CPn0281.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9Z8Q7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG1830.
    HOGENOMiHOG000224791.
    KOiK11645.
    OMAiGIEHTAG.
    OrthoDBiEOG6JQGZX.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    InterProiIPR013785. Aldolase_TIM.
    IPR002915. DeoC/FbaB/lacD_aldolase.
    [Graphical view]
    PfamiPF01791. DeoC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9Z8Q7-1 [UniParc]FASTAAdd to Basket

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    MLNIHDILGN DDENLLSYQC KHITKDKLTL PSHDFVDKVF GLSDRNNRVL    50
    RSLQTMFSHG RLANSGYLSI LPVDQGIEHS AGASFAINPI YFDPENIVKL 100
    AIESGCSAVA STYGTLSLLS RKYAHKIPFM LKLNHNELLS YPTKYHQIFF 150
    TQVEAAYSMG AVAVGATVYF GSETSNEEIV AVSNAFAKAR SLGLATVLWC 200
    YLRNPAFVAN GVDYHTAADL TGQADHLGAT LGADIVKQKL PTCQGGFKAI 250
    NFGKTDERVY SELSSNHPID LCRYQVLNSY CGKVGLINSG GPSGKNDFTE 300
    AARTAVINKR AGGMGLILGR KAFQRPLSEG IQLLNLVQDI YLDPNITIA 349
    Length:349
    Mass (Da):38,028
    Last modified:May 1, 1999 - v1
    Checksum:i69882529D685C7D9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE001363 Genomic DNA. Translation: AAD18430.1.
    AE002161 Genomic DNA. Translation: AAF38310.1.
    BA000008 Genomic DNA. Translation: BAA98491.1.
    AE009440 Genomic DNA. Translation: AAP98222.1.
    PIRiA86526.
    C72097.
    RefSeqiNP_224486.1. NC_000922.1.
    NP_300340.1. NC_002491.1.
    NP_445024.1. NC_002179.2.
    NP_876565.1. NC_005043.1.

    Genome annotation databases

    EnsemblBacteriaiAAD18430; AAD18430; CPn_0281.
    AAF38310; AAF38310; CP_0477.
    AAP98222; AAP98222; CpB0289.
    BAA98491; BAA98491; BAA98491.
    GeneIDi1466972.
    894851.
    919064.
    963038.
    KEGGicpa:CP0477.
    cpj:CPj0281.
    cpn:CPn0281.
    cpt:CpB0289.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE001363 Genomic DNA. Translation: AAD18430.1 .
    AE002161 Genomic DNA. Translation: AAF38310.1 .
    BA000008 Genomic DNA. Translation: BAA98491.1 .
    AE009440 Genomic DNA. Translation: AAP98222.1 .
    PIRi A86526.
    C72097.
    RefSeqi NP_224486.1. NC_000922.1.
    NP_300340.1. NC_002491.1.
    NP_445024.1. NC_002179.2.
    NP_876565.1. NC_005043.1.

    3D structure databases

    ProteinModelPortali Q9Z8Q7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 115713.CPn0281.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAD18430 ; AAD18430 ; CPn_0281 .
    AAF38310 ; AAF38310 ; CP_0477 .
    AAP98222 ; AAP98222 ; CpB0289 .
    BAA98491 ; BAA98491 ; BAA98491 .
    GeneIDi 1466972.
    894851.
    919064.
    963038.
    KEGGi cpa:CP0477.
    cpj:CPj0281.
    cpn:CPn0281.
    cpt:CpB0289.

    Phylogenomic databases

    eggNOGi COG1830.
    HOGENOMi HOG000224791.
    KOi K11645.
    OMAi GIEHTAG.
    OrthoDBi EOG6JQGZX.

    Enzyme and pathway databases

    BioCyci CPNE115711:GI7B-492-MONOMER.
    CPNE115713:GHEY-295-MONOMER.
    CPNE138677:GH8N-292-MONOMER.
    CPNE182082:GH4N-301-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    InterProi IPR013785. Aldolase_TIM.
    IPR002915. DeoC/FbaB/lacD_aldolase.
    [Graphical view ]
    Pfami PF01791. DeoC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CWL029.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AR39.
    3. "Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA."
      Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K., Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.
      Nucleic Acids Res. 28:2311-2314(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: J138.
    4. "The genome sequence of Chlamydia pneumoniae TW183 and comparison with other Chlamydia strains based on whole genome sequence analysis."
      Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P., Schneider S., Pohl T., Essig A., Marre R., Melchers K.
      Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: TW-183.

    Entry informationi

    Entry nameiALF1_CHLPN
    AccessioniPrimary (citable) accession number: Q9Z8Q7
    Secondary accession number(s): Q9JQ77
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2000
    Last sequence update: May 1, 1999
    Last modified: October 1, 2014
    This is version 83 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3