Reviewed, UniProtKB/Swiss-Prot Q9Z8N1 (PHSG_CHLPN)

Names and origin

Protein names

Recommended name:
    Glycogen phosphorylase
    EC=2.4.1.1

Gene names

Name:	glgP
Ordered Locus Names:	CPn_0307, CP_0451, CpB0316

Organism

Chlamydia pneumoniae (Chlamydophila pneumoniae) [Complete proteome] [HAMAP]

Taxonomic identifier

83558 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydophila

Protein attributes

Sequence length	824 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties By similarity.
Catalytic activity	(1,4-alpha-D-glucosyl)(n) + phosphate = (1,4-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate.
Cofactor	Pyridoxal phosphate By similarity.
Sequence similarities	Belongs to the glycogen phosphorylase family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glycogen metabolism
Ligand	Pyridoxal phosphate
Molecular function	Glycosyltransferase Transferase
Technical term	Allosteric enzyme Complete proteome
Gene Ontology (GO)
Biological process	glycogen metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	phosphorylase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 824	824	Glycogen phosphorylase		PRO_0000188551
Amino acid modifications
	Modified residue	667	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9Z8N1-1 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: B71EA8654A3ECBAC	FASTA	824	94,517
	10 20 30 40 50 60 MEDFSSFDKN KVSVDSMKRA ILDRLYLSVV QSPESASPRD IFTAVAKTVM EWLAKGWLKT 70 80 90 100 110 120 QNGYYKNDVK RVYYLSMEFL LGRSLKSNLL NLGILDLVRK ALKTLNYDFD HLVEMESDAG 130 140 150 160 170 180 LGNGGLGRLA ACYLDSMATL AVPAYGYGIR YDYGIFDQRI VNGYQEEAPD EWLRYGNPWE 190 200 210 220 230 240 ICRGEYLYPV RFYGRVIHYT DSRGKQVADL VDTQEVLAMA YDIPIPGYGN DTVNSLRLWQ 250 260 270 280 290 300 AQSPRGFEFS YFNHGNYIQA IEDIALIENI SRVLYPNDSI TEGQELRLKQ EYFLVSATIQ 310 320 330 340 350 360 DIIRRYTKTH ICLDNLADKV VVQLNDTHPA LGIAEMMHIL VDREELPWDK AWEMTTVIFN 370 380 390 400 410 420 YTNHTILPEA LERWPLDLFS KLLPRHLEII YEINSRWLEK VGSRYPKNDD KRRSLSIVEE 430 440 450 460 470 480 GYQKRINMAN LAVVGSAKVN GVSSFHSQLI KDTLFKEFYE FFPEKFINVT NGVTPRRWIA 490 500 510 520 530 540 LCNPRLSKLL NETIGDRYII DLSHLSLIRS FAEDSGFRDH WKGVKLKNKQ DLTSRIYNEV 550 560 570 580 590 600 GEIVDPNSLF DCHIKRIHEY KRQLMNILRV IYVYNDLKEN PNQDVVPTTV IFSGKAAPGY 610 620 630 640 650 660 VMAKLIIKLI NSVADVVNQD SRVNDKLKVL FLPNYRVSMA EHIIPGTDLS EQISTAGMEA 670 680 690 700 710 720 SGTGNMKFAL NGALTIGTMD GANIEMAEHI GKENMFIFGL LEEQIVQLRR EYCPQTICDK 730 740 750 760 770 780 NPKIRQVLDL LEQGFFNSND KDLFKPIVHR LLHEGDPFFV LADLESYIAA HENVNKLFKE 790 800 810 820 PDSWTKISIY NTAGMGFFSS DRAIQDYARD IWHVPTKSCS GEGN

References

[1]	"Comparative genomes of Chlamydia pneumoniae and C. trachomatis." Kalman S., Mitchell W.P., Marathe R., Lammel C.J., Fan J., Hyman R.W., Olinger L., Grimwood J., Davis R.W., Stephens R.S. Nat. Genet. 21:385-389(1999) [PubMed: 10192388] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CWL029.
[2]	"Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39." Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O., Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S., Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J., Gwinn M.L. , Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G., Salzberg S.L., Eisen J.A., Fraser C.M. Nucleic Acids Res. 28:1397-1406(2000) [PubMed: 10684935] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AR39.
[3]	"Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA." Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K., Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T. Nucleic Acids Res. 28:2311-2314(2000) [PubMed: 10871362] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: J138.
[4]	"The genome sequence of Chlamydia pneumoniae TW183 and comparison with other Chlamydia strains based on whole genome sequence analysis." Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P., Schneider S., Pohl T., Essig A., Marre R., Melchers K. Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TW-183.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE001363 Genomic DNA. Translation: AAD18456.1. AE002161 Genomic DNA. Translation: AAF38289.1. BA000008 Genomic DNA. Translation: BAA98517.1. AE009440 Genomic DNA. Translation: AAP98249.1.
PIR	C72095. C86529.
RefSeq	NP_224512.1. NP_300366.1. NP_444999.1. NP_876592.1.
3D structure databases
SMR	Q9Z8N1. Positions 13-817.
ModBase	Search...
Protein family/group databases
CAZy	GT35. Glycosyltransferase Family 35.
2-D gel databases
PHCI-2DPAGE	Q9Z8N1.
Genome annotation databases
GeneID	1466999. 895140. 919076. 963783.
GenomeReviews	Gene locus CPn_0307 in contig AE001363_GR. Gene locus CP_0451 in contig AE002161_GR. Gene locus CpB0316 in contig AE009440_GR. Gene locus glgP in contig BA000008_GR.
KEGG	cpa:CP0451. cpn:CPn0307. cpt:CpB0316.
TIGR	CP_0451.
Phylogenomic databases
HOGENOM	HBG444050.
OMA	VAIHLND.
PhylomeDB	Q9Z8N1.
Enzyme and pathway databases
BioCyc	CPNE115711:CP_0451-MONOMER. CPNE115713:CPN0307-MONOMER. CPNE138677:CPJ0307-MONOMER. CPNE182082:CPB0316-MONOMER.
BRENDA	2.4.1.1. 264832.
Family and domain databases
InterPro	IPR011833. Glycg_phsphrylas. IPR000811. Glyco_trans_35. [Graphical view]
PANTHER	PTHR11468. Glyco_trans_35. 1 hit.
Pfam	PF00343. Phosphorylase. 1 hit. [Graphical view]
PIRSF	PIRSF000460. Pprylas_GlgP. 1 hit.
TIGRFAMs	TIGR02093. P_ylase. 1 hit.
PROSITE	PS00102. PHOSPHORYLASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PHSG_CHLPN

Accession

Primary (citable) accession number: Q9Z8N1
Secondary accession number(s): Q9JQ49

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	May 1, 1999
Last modified:	February 9, 2010
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)