Q9Z8L2 (MALQ_CHLPN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
4-alpha-glucanotransferase
EC=2.4.1.25

Alternative name(s):
Amylomaltase
Disproportionating enzyme
Short name=D-enzyme

Gene names

Name:	malQ
Ordered Locus Names:	CPn_0326, CP_0431, CpB0336

Organism

Chlamydia pneumoniae (Chlamydophila pneumoniae) [Complete proteome] [HAMAP]

Taxonomic identifier

83558 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydia

Protein attributes

Sequence length	526 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Transfers a segment of a (1->4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1->4)-alpha-D-glucan.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the disproportionating enzyme family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism
Cellular component	Cytoplasm
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	4-alpha-glucanotransferase activity Inferred from electronic annotation. Source: EC cation binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 526	526	4-alpha-glucanotransferase		PRO_0000170121

Sequences

	Sequence		Length	Mass (Da)
	Q9Z8L2 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: C192994118996CB3	FASTA	526	60,993
	10 20 30 40 50 60 MNVLKYTKHS PSAHAWKLIG TSPKHGIYLP LFSIHTKNSC GIGEFLDLIP LISWCQKQGF 70 80 90 100 110 120 SVIQLLPLND TGEDTSPYNS ISSVALNPLF LSLSSLPNID TIPEVAKKLQ DMHELCSTPS 130 140 150 160 170 180 VSYTQVKEKK WAFLREYYQK CCKSSLEGNS NFSEFLESER YWLYPYGTFR AIKHHMHGEP 190 200 210 220 230 240 INNWPKSLTD QENFPDLTKK FHDEVLFFSY LQFLCYQQLC EVKAYADQHH VLLKGDLPIL 250 260 270 280 290 300 ISKDSCDVWY FRDYFSSSRS VGAPPDLYNS EGQNWHLPIY NFSQLAKDDY IWWKERLRYA 310 320 330 340 350 360 QNFYSVYRLD HIIGFFRLWI WDSSGRGRFI PDNPKDYIKQ GTEILSTMLG ASSMLPIGED 370 380 390 400 410 420 LGIIPQDVKT TLTHLGICGT RIPRWERNWE SDSAFIPLKD YNPLSVTTLS THDSDTFAQW 430 440 450 460 470 480 WLNSPKEAKQ FAKFLHLPFQ KTLTTETQID ILKLSHESAS IFHINLFNDY LALCPDLVSK 490 500 510 520 NLQRERINTP GTISKKNWSY RVRPSLEELA IHKKFNGYIE KILTGL

References

[1]	"Comparative genomes of Chlamydia pneumoniae and C. trachomatis." Kalman S., Mitchell W.P., Marathe R., Lammel C.J., Fan J., Hyman R.W., Olinger L., Grimwood J., Davis R.W., Stephens R.S. Nat. Genet. 21:385-389(1999) [PubMed: 10192388] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CWL029.
[2]	"Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39." Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O., Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S., Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J., Gwinn M.L. , Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G., Salzberg S.L., Eisen J.A., Fraser C.M. Nucleic Acids Res. 28:1397-1406(2000) [PubMed: 10684935] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AR39.
[3]	"Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA." Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K., Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T. Nucleic Acids Res. 28:2311-2314(2000) [PubMed: 10871362] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: J138.
[4]	"The genome sequence of Chlamydia pneumoniae TW183 and comparison with other Chlamydia strains based on whole genome sequence analysis." Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P., Schneider S., Pohl T., Essig A., Marre R., Melchers K. Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TW-183.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE001363 Genomic DNA. Translation: AAD18475.1. AE002161 Genomic DNA. Translation: AAF38273.1. BA000008 Genomic DNA. Translation: BAA98536.1. AE009440 Genomic DNA. Translation: AAP98269.1.
PIR	F86531. G72091.
RefSeq	NP_224531.1. NC_000922.1. NP_300385.1. NC_002491.1. NP_444979.1. NC_002179.2. NP_876612.1. NC_005043.1.
3D structure databases
ProteinModelPortal	Q9Z8L2.
ModBase	Search...
Protein family/group databases
CAZy	GH77. Glycoside Hydrolase Family 77.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1467019. 895084. 919102. 963236.
GenomeReviews	Gene locus CPn_0326 in contig AE001363_GR. Gene locus CP_0431 in contig AE002161_GR. Gene locus CpB0336 in contig AE009440_GR. Gene locus malQ in contig BA000008_GR.
KEGG	cpa:CP0431. cpn:CPn0326. cpt:CpB0336.
TIGR	CP_0431.
Phylogenomic databases
HOGENOM	HBG413941.
OMA	VATTGTH.
ProtClustDB	PRK14508.
Enzyme and pathway databases
BioCyc	CPNE115711:CP_0431-MONOMER. CPNE115713:CPN0326-MONOMER. CPNE138677:CPJ0326-MONOMER. CPNE182082:CPB0336-MONOMER.
Family and domain databases
InterPro	IPR003385. Glyco_hydro_77. IPR013781. Glyco_hydro_subgr_catalytic. IPR017853. Glycoside_hydrolase_SF. [Graphical view]
Gene3D	G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.
KO	K00705.
Pfam	PF02446. Glyco_hydro_77. 1 hit. [Graphical view]
SUPFAM	SSF51445. Glyco_hydro_cat. 1 hit.
TIGRFAMs	TIGR00217. MalQ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MALQ_CHLPN

Accession

Primary (citable) accession number: Q9Z8L2
Secondary accession number(s): Q9JQ41

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	May 1, 1999
Last modified:	January 25, 2012
This is version 77 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program