Reviewed,
UniProtKB/Swiss-Prot Q9Z8I3 (6PGD_CHLPN)
Last modified
November 4, 2008.
Version 62.
History...
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90%,
50% identity |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: 6-phosphogluconate dehydrogenase, decarboxylating EC=1.1.1.44 | ||||
| Gene names |
| ||||
| Organism | Chlamydia pneumoniae (Chlamydophila pneumoniae) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 83558 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydophila |
Protein attributes
| Sequence length | 479 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | 6-phospho-D-gluconate + NADP(+) = D-ribulose 5-phosphate + CO(2) + NADPH. |
| Pathway | |
| Sequence similarities | Belongs to the 6-phosphogluconate dehydrogenase family. |
Ontologies
Keywords | |
|---|---|
| Biological process | Gluconate utilization Pentose shunt |
| Ligand | NADP |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
Gene Ontology (GO) | |
| Biological process | D-gluconate metabolic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 479 | 479 | 6-phosphogluconate dehydrogenase, decarboxylating | PRO_0000090032 | |||
Sequences
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References
| [1] | "Comparative genomes of Chlamydia pneumoniae and C. trachomatis." Kalman S., Mitchell W.P., Marathe R., Lammel C.J., Fan J., Hyman R.W., Olinger L., Grimwood J., Davis R.W., Stephens R.S. Nat. Genet. 21:385-389(1999) [PubMed: 10192388] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CWL029. |
| [2] | "Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39." Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O., Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S., Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J., Gwinn M.L. Fraser C.M.Nucleic Acids Res. 28:1397-1406(2000) [PubMed: 10684935] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AR39. |
| [3] | "Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA." Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K., Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T. Nucleic Acids Res. 28:2311-2314(2000) [PubMed: 10871362] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: J138. |
| [4] | "The genome sequence of Chlamydia pneumoniae TW183 and comparison with other Chlamydia strains based on whole genome sequence analysis." Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P., Schneider S., Pohl T., Essig A., Marre R., Melchers K. Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TW-183. |
Cross-references
Sequence databases | |
|---|---|
| AE001363 Genomic DNA. Translation: AAD18504.1. AE002161 Genomic DNA. Translation: AAF38243.1. BA000008 Genomic DNA. Translation: BAA98568.1. AE017158 Genomic DNA. Translation: AAP98300.1. | |
| PIR | C72088. F86535. |
| RefSeq | NP_224560.1. NP_300417.1. NP_444947.1. NP_876643.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 2PGD based on UniProtKB P00349. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 1467050. 895135. 919866. 963777. |
| GenomeReviews | Gene locus CP_0398 in contig AE002161_GR. Gene locus CpB0369 in contig AE009440_GR. Gene locus CPn_0360 in contig AE001363_GR. Gene locus gnd in contig BA000008_GR. |
| KEGG | cpa:CP0398. cpn:CPn0360. cpt:CpB0369. |
| TIGR | CP_0398. |
Phylogenomic databases | |
| HOGENOM | Q9Z8I3. |
Enzyme and pathway databases | |
| BioCyc | CPNE115711:CP_0398-MON. CPNE115713:CPN0360-MON. CPNE138677:CPJ0360-MON. CPNE182082:CPB0369-MON. |
Family and domain databases | |
| InterPro | IPR006183. 6-phosphogluconate_DHase. IPR006114. 6PGDH_C. IPR006113. 6PGDH_decarbox. IPR006115. 6PGDH_NAD-bd. IPR006184. 6PGdom_BS. IPR013328. DHase_multihelical. IPR012284. Fibritin/6PGD_C-extension. IPR016040. NAD(P)-bd. [Graphical view] |
| Gene3D | G3DSA:1.20.5.320. Fibritin/6PGD_C-extension. 1 hit. G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. G3DSA:1.10.1040.10. Opine_DH. 1 hit. |
| Pfam | PF00393. 6PGD. 1 hit. PF03446. NAD_binding_2. 1 hit. [Graphical view] |
| PRINTS | PR00076. 6PGDHDRGNASE. |
| TIGRFAMs | TIGR00873. gnd. 1 hit. |
| PROSITE | PS00461. 6PGD. 1 hit. [Graphical view] |
| BLOCKS | Search... |
| ProtoNet | Search... |
Entry information
| Entry name | 6PGD_CHLPN | ||||||||
| Accession | Primary (citable) accession number: Q9Z8I3 Secondary accession number(s): Q9JQC1 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| UniProtKB secondary accession numbers Index of UniProtKB secondary accession numbers |
| SIMILARITY comments Index of protein domains and families |

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