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Protein
Submitted name:

2-oxoglutarate dehydrogenase, E1 component

Gene

sucA

Organism
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: InterPro
  2. thiamine pyrophosphate binding Source: InterPro

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciCPNE115711:GI7B-392-MONOMER.
CPNE115713:GHEY-393-MONOMER.
CPNE138677:GH8N-388-MONOMER.
CPNE182082:GH4N-401-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
2-oxoglutarate dehydrogenase, E1 componentImported
Submitted name:
2-oxoglutarate dehydrogenase, E1 subunitImported
Submitted name:
Oxoglutarate DehydrogenaseImported
Submitted name:
Oxoglutarate dehydrogenaseImported
Gene namesi
Name:sucAImported
Ordered Locus Names:CP_0378Imported, CpB0390Imported, CPn_0378Imported
OrganismiChlamydia pneumoniae (Chlamydophila pneumoniae)Imported
Taxonomic identifieri83558 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
ProteomesiUP000000802 Componenti: Chromosome UP000000583 Componenti: Chromosome UP000000801 Componenti: Chromosome UP000000424 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi115713.CPn0378.

Structurei

3D structure databases

ProteinModelPortaliQ9Z8G5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000259588.
KOiK00164.
OMAiNFTQPLM.
OrthoDBiEOG6V1M1F.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9Z8G5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSEFVGQVY SSDMDWIESM YQRFMNHETL DPSWKYFFEG YQLGQAASPS
60 70 80 90 100
EASTKISGNE TIAMLQEQKS QFLCTIYRYY GYLQSQISTL APTTDSRFIQ
110 120 130 140 150
EKIAKIDLDE QVPSAGLLPK AQVSVRELIE ALKKCYCGSL TLETLTCTPE
160 170 180 190 200
LQEFVWNLME KRQVERFAEQ LLRSYKDLCK ATFFEEFLQI KFTGQKRFSL
210 220 230 240 250
EGGETLVPML EHLVHYGSAL GISNYVLGMA HRGRLNVLTN VLGKPYRYVF
260 270 280 290 300
MEFEDDPAAR GLESVGDVKY HKGYVLKSHQ KDRETTFVML PNASHLESVD
310 320 330 340 350
PIVEGVVAAL QHQGHAGKEQ SSLAILVHGD AAFSGQGVVY ETLQLSRVPG
360 370 380 390 400
YSTEGTLHIV VNNYIGFTAV PRESRSTPYC TDIAKMLGIP VFRVNSEDVV
410 420 430 440 450
ACIEAIEYAL QVRERFSCDV IIDLCCYRKY GHNESDDPSV TAPLLYDQIK
460 470 480 490 500
RKKSIRELFR QYLLEGQFAD ISEETLASIE KEIQESLNRE FQVLKGTDPE
510 520 530 540 550
PFPKKECHHC DRLNNGELIL HDCDVSLDRE TLFHMSSRLC GFPDNFHPHP
560 570 580 590 600
KIKTLLEKRM KMAEGGVGYD WAMAEELAFA SLLIEGYNLR LSGQDSIRGT
610 620 630 640 650
FSQRHLVWSD TVTGDTYSPL YHLSAEQGSV EMYNSPLSEY AILGFEYGYA
660 670 680 690 700
QQALKTLVLW EAQFGDFANG AQIIFDQYIS SGIQKWDLHS DIVLLLPHGY
710 720 730 740 750
EGQGPEHSSS RIERYLQLAA NWNFQVVLPS TPVQYFRILR EHAKRDLSLP
760 770 780 790 800
LVIFTPKLLL RYPQCVSSIE EFTEPGGFRA ILEDADPNYD ASILVLCSGK
810 820 830 840 850
IYYDYAEMLP QDRRKDFSCL RIESLYPLAL EDLVSLIDKY SHLKHFVWLQ
860 870 880 890 900
EESKNMGAYD YMFMALQDIL PEKLLYIGRP RSSSTASGSA KLSRQELVTC

METLFSLR
Length:908
Mass (Da):103,470
Last modified:May 1, 1999 - v1
Checksum:iF6B29DA79FA8146D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001363 Genomic DNA. Translation: AAD18522.1.
AE002161 Genomic DNA. Translation: AAF38225.1.
AE009440 Genomic DNA. Translation: AAP98321.1.
BA000008 Genomic DNA. Translation: BAA98586.1.
PIRiG72085.
H86537.
RefSeqiNP_224578.1. NC_000922.1.
NP_300435.1. NC_002491.1.
NP_444926.1. NC_002179.2.
NP_876664.1. NC_005043.1.

Genome annotation databases

EnsemblBacteriaiAAD18522; AAD18522; CPn_0378.
AAF38225; AAF38225; CP_0378.
AAP98321; AAP98321; CpB0390.
BAA98586; BAA98586; BAA98586.
GeneIDi894939.
962842.
KEGGicpa:CP0378.
cpj:CPj0378.
cpn:CPn0378.
cpt:CpB0390.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001363 Genomic DNA. Translation: AAD18522.1.
AE002161 Genomic DNA. Translation: AAF38225.1.
AE009440 Genomic DNA. Translation: AAP98321.1.
BA000008 Genomic DNA. Translation: BAA98586.1.
PIRiG72085.
H86537.
RefSeqiNP_224578.1. NC_000922.1.
NP_300435.1. NC_002491.1.
NP_444926.1. NC_002179.2.
NP_876664.1. NC_005043.1.

3D structure databases

ProteinModelPortaliQ9Z8G5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi115713.CPn0378.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD18522; AAD18522; CPn_0378.
AAF38225; AAF38225; CP_0378.
AAP98321; AAP98321; CpB0390.
BAA98586; BAA98586; BAA98586.
GeneIDi894939.
962842.
KEGGicpa:CP0378.
cpj:CPj0378.
cpn:CPn0378.
cpt:CpB0390.

Phylogenomic databases

HOGENOMiHOG000259588.
KOiK00164.
OMAiNFTQPLM.
OrthoDBiEOG6V1M1F.

Enzyme and pathway databases

BioCyciCPNE115711:GI7B-392-MONOMER.
CPNE115713:GHEY-393-MONOMER.
CPNE138677:GH8N-388-MONOMER.
CPNE182082:GH4N-401-MONOMER.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CWL029Imported.
  2. "Comparison of Outer Membrane Protein Genes omp and pmp in the Whole Genome Sequences of Chlamydia pneumoniae Isolates from Japan and the United States."
    Shirai M., Hirakawa H., Ouchi K., Tabuchi M., Kishi F., Kimoto M., Takeuchi A., Nishida J., Shibata K., Fujinaga R., Yoneda H., Matsushima H., Tanaka C., Furukawa S., Miura K., Nakazawa A., Ishii K., Shiba T.
    , Hattori M., Kuhara S., Nakazawa T.
    J. Infect. Dis. 181:524-527(1999)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: J138Imported.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AR39Imported.
  4. "Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA."
    Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K., Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.
    Nucleic Acids Res. 28:2311-2314(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: J138Imported.
  5. "The genome sequence of Chlamydia pneumoniae TW183 and comparison with other Chlamydia strains based on whole genome sequence analysis."
    Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P., Schneider S., Pohl T., Essig A., Marre R., Melchers K.
    Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TW-183Imported.

Entry informationi

Entry nameiQ9Z8G5_CHLPN
AccessioniPrimary (citable) accession number: Q9Z8G5
Secondary accession number(s): Q7AIW3, Q7BXF4, Q7DER5
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: April 1, 2015
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.