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Protein

Deoxycytidine triphosphate deaminase

Gene

dcd

Organism
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

dCTP + H2O = dUTP + NH3.

Pathwayi

GO - Molecular functioni

  1. dCTP deaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. dUMP biosynthetic process Source: UniProtKB-UniPathway
  2. dUTP biosynthetic process Source: InterPro
  3. pyrimidine ribonucleotide biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Nucleotide metabolism

Enzyme and pathway databases

BioCyciCPNE115711:GI7B-377-MONOMER.
CPNE115713:GHEY-407-MONOMER.
CPNE138677:GH8N-402-MONOMER.
CPNE182082:GH4N-415-MONOMER.
UniPathwayiUPA00610; UER00665.

Names & Taxonomyi

Protein namesi
Recommended name:
Deoxycytidine triphosphate deaminase (EC:3.5.4.13)
Short name:
dCTP deaminase
Gene namesi
Name:dcd
Ordered Locus Names:CPn_0392, CP_0363, CpB0404
OrganismiChlamydia pneumoniae (Chlamydophila pneumoniae)
Taxonomic identifieri83558 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
ProteomesiUP000000424: Chromosome, UP000000583: Chromosome, UP000000801: Chromosome, UP000000802: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 190190Deoxycytidine triphosphate deaminasePRO_0000155976Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi115713.CPn0392.

Structurei

3D structure databases

ProteinModelPortaliQ9Z8F1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the dCTP deaminase family.Curated

Phylogenomic databases

eggNOGiCOG0717.
HOGENOMiHOG000228600.
KOiK01494.
OMAiMEYFRIP.
OrthoDBiEOG67DPKR.

Family and domain databases

Gene3Di2.70.40.10. 1 hit.
HAMAPiMF_00146. dCTP_deaminase.
InterProiIPR011962. dCTP_deam.
IPR029054. dUTPase-like.
IPR008180. dUTPase/dCTP_deaminase.
[Graphical view]
PfamiPF00692. dUTPase. 1 hit.
[Graphical view]
SUPFAMiSSF51283. SSF51283. 1 hit.
TIGRFAMsiTIGR02274. dCTP_deam. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9Z8F1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSIKEDKWIR EMALNADMIH PFVNGQVNVN EETGEKLISY GLSSYGYDLR
60 70 80 90 100
LSREFKVFTN VYNSVVDPKC FTEDIFISIT DDVCIVPPNS FALARSVEYF
110 120 130 140 150
RIPRNVLTMC IGKSTYARCG IIVNVTPFEP EWEGHVTIEI SNTTPLPAKI
160 170 180 190
YANEGIAQVL FFESSTTCEV SYADRKGKYQ KQQGITVPCV
Length:190
Mass (Da):21,475
Last modified:May 1, 1999 - v1
Checksum:i7F1DB26849E63B7F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001363 Genomic DNA. Translation: AAD18535.1.
AE002161 Genomic DNA. Translation: AAF38212.1.
BA000008 Genomic DNA. Translation: BAA98600.1.
AE009440 Genomic DNA. Translation: AAP98335.1.
PIRiF72084.
F86539.
RefSeqiNP_224592.1. NC_000922.1.
NP_300449.1. NC_002491.1.
NP_444911.1. NC_002179.2.
NP_876678.1. NC_005043.1.

Genome annotation databases

EnsemblBacteriaiAAD18535; AAD18535; CPn_0392.
AAF38212; AAF38212; CP_0363.
AAP98335; AAP98335; CpB0404.
BAA98600; BAA98600; BAA98600.
GeneIDi1467085.
894877.
919239.
963059.
KEGGicpa:CP0363.
cpj:CPj0392.
cpn:CPn0392.
cpt:CpB0404.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001363 Genomic DNA. Translation: AAD18535.1.
AE002161 Genomic DNA. Translation: AAF38212.1.
BA000008 Genomic DNA. Translation: BAA98600.1.
AE009440 Genomic DNA. Translation: AAP98335.1.
PIRiF72084.
F86539.
RefSeqiNP_224592.1. NC_000922.1.
NP_300449.1. NC_002491.1.
NP_444911.1. NC_002179.2.
NP_876678.1. NC_005043.1.

3D structure databases

ProteinModelPortaliQ9Z8F1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi115713.CPn0392.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD18535; AAD18535; CPn_0392.
AAF38212; AAF38212; CP_0363.
AAP98335; AAP98335; CpB0404.
BAA98600; BAA98600; BAA98600.
GeneIDi1467085.
894877.
919239.
963059.
KEGGicpa:CP0363.
cpj:CPj0392.
cpn:CPn0392.
cpt:CpB0404.

Phylogenomic databases

eggNOGiCOG0717.
HOGENOMiHOG000228600.
KOiK01494.
OMAiMEYFRIP.
OrthoDBiEOG67DPKR.

Enzyme and pathway databases

UniPathwayiUPA00610; UER00665.
BioCyciCPNE115711:GI7B-377-MONOMER.
CPNE115713:GHEY-407-MONOMER.
CPNE138677:GH8N-402-MONOMER.
CPNE182082:GH4N-415-MONOMER.

Family and domain databases

Gene3Di2.70.40.10. 1 hit.
HAMAPiMF_00146. dCTP_deaminase.
InterProiIPR011962. dCTP_deam.
IPR029054. dUTPase-like.
IPR008180. dUTPase/dCTP_deaminase.
[Graphical view]
PfamiPF00692. dUTPase. 1 hit.
[Graphical view]
SUPFAMiSSF51283. SSF51283. 1 hit.
TIGRFAMsiTIGR02274. dCTP_deam. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CWL029.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AR39.
  3. "Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA."
    Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K., Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.
    Nucleic Acids Res. 28:2311-2314(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: J138.
  4. "The genome sequence of Chlamydia pneumoniae TW183 and comparison with other Chlamydia strains based on whole genome sequence analysis."
    Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P., Schneider S., Pohl T., Essig A., Marre R., Melchers K.
    Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TW-183.

Entry informationi

Entry nameiDCD_CHLPN
AccessioniPrimary (citable) accession number: Q9Z8F1
Secondary accession number(s): Q9JQ65
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 1999
Last modified: January 7, 2015
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.