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Protein

Phosphatidate cytidylyltransferase

Gene

cdsA

Organism
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

CTP + phosphatidate = diphosphate + CDP-diacylglycerol.

Pathwayi: CDP-diacylglycerol biosynthesis

This protein is involved in step 3 of the subpathway that synthesizes CDP-diacylglycerol from sn-glycerol 3-phosphate.
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. no protein annotated in this organism
  3. Phosphatidate cytidylyltransferase (cdsA)
This subpathway is part of the pathway CDP-diacylglycerol biosynthesis, which is itself part of Phospholipid metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CDP-diacylglycerol from sn-glycerol 3-phosphate, the pathway CDP-diacylglycerol biosynthesis and in Phospholipid metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferase, Transferase
Biological processLipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

Enzyme and pathway databases

UniPathwayiUPA00557; UER00614

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphatidate cytidylyltransferase (EC:2.7.7.41)
Alternative name(s):
CDP-DAG synthase
CDP-DG synthase
CDP-diacylglycerol synthase
Short name:
CDS
CDP-diglyceride pyrophosphorylase
CDP-diglyceride synthase
CTP:phosphatidate cytidylyltransferase
Gene namesi
Name:cdsA
Ordered Locus Names:CPn_0567, CP_0182, CpB0589
OrganismiChlamydia pneumoniae (Chlamydophila pneumoniae)
Taxonomic identifieri83558 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
Proteomesi
  • UP000000583 Componenti: Chromosome
  • UP000000801 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei30 – 50HelicalSequence analysisAdd BLAST21
Transmembranei73 – 93HelicalSequence analysisAdd BLAST21
Transmembranei100 – 120HelicalSequence analysisAdd BLAST21
Transmembranei127 – 147HelicalSequence analysisAdd BLAST21
Transmembranei167 – 187HelicalSequence analysisAdd BLAST21
Transmembranei205 – 225HelicalSequence analysisAdd BLAST21
Transmembranei235 – 255HelicalSequence analysisAdd BLAST21
Transmembranei280 – 300HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000907321 – 308Phosphatidate cytidylyltransferaseAdd BLAST308

Interactioni

Protein-protein interaction databases

STRINGi182082.CpB0589

Family & Domainsi

Sequence similaritiesi

Belongs to the CDS family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0575 LUCA
HOGENOMiHOG000034746
KOiK00981
OMAiEVFWIST
OrthoDBiPOG091H001F

Sequencei

Sequence statusi: Complete.

Q9Z7Y6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLNSNKFKSK TGAYGDLFQR VVVHSLVLTF LVLLLYSSLF PLTSFALGFI
60 70 80 90 100
TATCGAVGTY EYSSMAKAKM HYPLSTFSAI GSFLFLALSF LSIRWGHSLP
110 120 130 140 150
GFFDALPWTL LIVWVVWSIF RVRKSTIGAL QLSGVTLFSI LYVGIPIRLF
160 170 180 190 200
LHVLYSFIHT QEPYLGIWWA SFLIATTKGA DIFGYFFGKA FGNKKIAPQI
210 220 230 240 250
SPNKTVVGFV AGCLGATLIS FIFFLQIPTR FASYFPMPAI LIPLGLALGI
260 270 280 290 300
TGFFGDIIES IFKRDAHLKN SNKLKAVGGM LDTLDSLLLS TPIAYLFLLI

TQSKEFIG
Length:308
Mass (Da):34,031
Last modified:May 1, 1999 - v1
Checksum:iF9B0135EE38D4E67
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001363 Genomic DNA Translation: AAD18707.1
AE002161 Genomic DNA Translation: AAF38055.1
BA000008 Genomic DNA Translation: BAA98773.1
AE009440 Genomic DNA Translation: AAP98518.1
PIRiC86561
H72062
RefSeqiNP_224763.1, NC_000922.1
WP_010883205.1, NZ_LN847257.1

Genome annotation databases

EnsemblBacteriaiAAD18707; AAD18707; CPn_0567
AAF38055; AAF38055; CP_0182
AAP98518; AAP98518; CpB0589
BAA98773; BAA98773; BAA98773
GeneIDi895339
KEGGicpa:CP_0182
cpj:cdsA
cpn:CPn0567
cpt:CpB0589
PATRICifig|115713.3.peg.632

Similar proteinsi

Entry informationi

Entry nameiCDSA_CHLPN
AccessioniPrimary (citable) accession number: Q9Z7Y6
Secondary accession number(s): Q9JQ17
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: March 28, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health