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Q9Z7Y6

- CDSA_CHLPN

UniProt

Q9Z7Y6 - CDSA_CHLPN

Protein

Phosphatidate cytidylyltransferase

Gene

cdsA

Organism
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 95 (01 Oct 2014)
      Sequence version 1 (01 May 1999)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    CTP + phosphatidate = diphosphate + CDP-diacylglycerol.

    Pathwayi

    GO - Molecular functioni

    1. phosphatidate cytidylyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. CDP-diacylglycerol biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Nucleotidyltransferase, Transferase

    Keywords - Biological processi

    Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

    Enzyme and pathway databases

    BioCyciCPNE115711:GI7B-193-MONOMER.
    CPNE115713:GHEY-586-MONOMER.
    CPNE138677:GH8N-578-MONOMER.
    CPNE182082:GH4N-601-MONOMER.
    UniPathwayiUPA00557; UER00614.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphatidate cytidylyltransferase (EC:2.7.7.41)
    Alternative name(s):
    CDP-DAG synthase
    CDP-DG synthase
    CDP-diacylglycerol synthase
    Short name:
    CDS
    CDP-diglyceride pyrophosphorylase
    CDP-diglyceride synthase
    CTP:phosphatidate cytidylyltransferase
    Gene namesi
    Name:cdsA
    Ordered Locus Names:CPn_0567, CP_0182, CpB0589
    OrganismiChlamydia pneumoniae (Chlamydophila pneumoniae)
    Taxonomic identifieri83558 [NCBI]
    Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
    ProteomesiUP000000424: Chromosome, UP000000583: Chromosome, UP000000801: Chromosome, UP000000802: Chromosome

    Subcellular locationi

    Cell membrane By similarity; Multi-pass membrane protein By similarity

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 308308Phosphatidate cytidylyltransferasePRO_0000090732Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi115713.CPn0567.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei30 – 5021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei73 – 9321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei100 – 12021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei127 – 14721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei167 – 18721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei205 – 22521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei235 – 25521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei280 – 30021HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the CDS family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0575.
    HOGENOMiHOG000034746.
    KOiK00981.
    OMAiTLFSILY.
    OrthoDBiEOG6TBHJT.

    Family and domain databases

    InterProiIPR000374. PC_trans.
    [Graphical view]
    PfamiPF01148. CTP_transf_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9Z7Y6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLNSNKFKSK TGAYGDLFQR VVVHSLVLTF LVLLLYSSLF PLTSFALGFI    50
    TATCGAVGTY EYSSMAKAKM HYPLSTFSAI GSFLFLALSF LSIRWGHSLP 100
    GFFDALPWTL LIVWVVWSIF RVRKSTIGAL QLSGVTLFSI LYVGIPIRLF 150
    LHVLYSFIHT QEPYLGIWWA SFLIATTKGA DIFGYFFGKA FGNKKIAPQI 200
    SPNKTVVGFV AGCLGATLIS FIFFLQIPTR FASYFPMPAI LIPLGLALGI 250
    TGFFGDIIES IFKRDAHLKN SNKLKAVGGM LDTLDSLLLS TPIAYLFLLI 300
    TQSKEFIG 308
    Length:308
    Mass (Da):34,031
    Last modified:May 1, 1999 - v1
    Checksum:iF9B0135EE38D4E67
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE001363 Genomic DNA. Translation: AAD18707.1.
    AE002161 Genomic DNA. Translation: AAF38055.1.
    BA000008 Genomic DNA. Translation: BAA98773.1.
    AE009440 Genomic DNA. Translation: AAP98518.1.
    PIRiC86561.
    H72062.
    RefSeqiNP_224763.1. NC_000922.1.
    NP_300622.1. NC_002491.1.
    NP_444733.1. NC_002179.2.
    NP_876861.1. NC_005043.1.

    Genome annotation databases

    EnsemblBacteriaiAAD18707; AAD18707; CPn_0567.
    AAF38055; AAF38055; CP_0182.
    AAP98518; AAP98518; CpB0589.
    BAA98773; BAA98773; BAA98773.
    GeneIDi1467268.
    895339.
    919325.
    962984.
    KEGGicpa:CP0182.
    cpj:CPj0567.
    cpn:CPn0567.
    cpt:CpB0589.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE001363 Genomic DNA. Translation: AAD18707.1 .
    AE002161 Genomic DNA. Translation: AAF38055.1 .
    BA000008 Genomic DNA. Translation: BAA98773.1 .
    AE009440 Genomic DNA. Translation: AAP98518.1 .
    PIRi C86561.
    H72062.
    RefSeqi NP_224763.1. NC_000922.1.
    NP_300622.1. NC_002491.1.
    NP_444733.1. NC_002179.2.
    NP_876861.1. NC_005043.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 115713.CPn0567.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAD18707 ; AAD18707 ; CPn_0567 .
    AAF38055 ; AAF38055 ; CP_0182 .
    AAP98518 ; AAP98518 ; CpB0589 .
    BAA98773 ; BAA98773 ; BAA98773 .
    GeneIDi 1467268.
    895339.
    919325.
    962984.
    KEGGi cpa:CP0182.
    cpj:CPj0567.
    cpn:CPn0567.
    cpt:CpB0589.

    Phylogenomic databases

    eggNOGi COG0575.
    HOGENOMi HOG000034746.
    KOi K00981.
    OMAi TLFSILY.
    OrthoDBi EOG6TBHJT.

    Enzyme and pathway databases

    UniPathwayi UPA00557 ; UER00614 .
    BioCyci CPNE115711:GI7B-193-MONOMER.
    CPNE115713:GHEY-586-MONOMER.
    CPNE138677:GH8N-578-MONOMER.
    CPNE182082:GH4N-601-MONOMER.

    Family and domain databases

    InterProi IPR000374. PC_trans.
    [Graphical view ]
    Pfami PF01148. CTP_transf_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CWL029.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AR39.
    3. "Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA."
      Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K., Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.
      Nucleic Acids Res. 28:2311-2314(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: J138.
    4. "The genome sequence of Chlamydia pneumoniae TW183 and comparison with other Chlamydia strains based on whole genome sequence analysis."
      Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P., Schneider S., Pohl T., Essig A., Marre R., Melchers K.
      Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: TW-183.

    Entry informationi

    Entry nameiCDSA_CHLPN
    AccessioniPrimary (citable) accession number: Q9Z7Y6
    Secondary accession number(s): Q9JQ17
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2000
    Last sequence update: May 1, 1999
    Last modified: October 1, 2014
    This is version 95 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3