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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligase (EC:6.1.1.19)
Alternative name(s):
Arginyl-tRNA synthetase
Short name:
ArgRS
Gene namesi
Name:argS
Ordered Locus Names:CPn_0570, CP_0179, CpB0593
OrganismiChlamydia pneumoniae (Chlamydophila pneumoniae)
Taxonomic identifieri83558 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
Proteomesi
  • UP000000583 Componenti: Chromosome
  • UP000000801 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001515461 – 561Arginine--tRNA ligaseAdd BLAST561

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi182082.CpB0593.

Structurei

3D structure databases

ProteinModelPortaliQ9Z7Y3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi123 – 133"HIGH" regionAdd BLAST11

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105C75. Bacteria.
COG0018. LUCA.
HOGENOMiHOG000247212.
KOiK01887.
OrthoDBiPOG091H01RF.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9Z7Y3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTLLSILSV ICSQAIAKAF PNLEDWAPEI TPSTKEHFGH YQCNDAMKLA
60 70 80 90 100
RVLKKAPRAI AEAIVAELPQ EPFSLIEIAG AGFINFTFSP VFLNQQLEHF
110 120 130 140 150
KDALKLGFQV SQPKKIIIDF SSPNIAKDMH VGHLRSTIIG DSLARIFSYV
160 170 180 190 200
GHDVLRLNHI GDWGTAFGML ITYLQENPCD YSDLEDLTSL YKKAYVCFTN
210 220 230 240 250
DEEFKKRSQQ NVVALQAKDP QAIAIWEKIC ETSEKAFQKI YDILDIVVEK
260 270 280 290 300
RGESFYNPFL PEIIEDLEKK GLLTVSNDAK CVFHEAFSIP FMVQKSDGGY
310 320 330 340 350
NYATTDLAAM RYRIEEDHAD KIIIVTDLGQ SLHFQLLEAT AIAAGYLQPG
360 370 380 390 400
IFSHVGFGLV LDPQGKKLKT RSGENVKLRE LLDTAIEKAE EALREHRPEL
410 420 430 440 450
TDEAIQERAP VIGINAIKYS DLSSHRTSDY VFSFEKMLRF EGNTAMFLLY
460 470 480 490 500
AYVRIQGIKR RLGISQLSLE GPPEIQEPAE ELLALTLLRF PEALESTIKE
510 520 530 540 550
LCPHFLTDYL YNLTHKFNGF FRDSHIQDSP YAKSRLFLCA LAEQVLATGM
560
HLLGLKTLER L
Length:561
Mass (Da):63,369
Last modified:May 1, 1999 - v1
Checksum:i6386F0FF190C22DB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001363 Genomic DNA. Translation: AAD18710.1.
AE002161 Genomic DNA. Translation: AAF38053.1.
BA000008 Genomic DNA. Translation: BAA98776.1.
AE009440 Genomic DNA. Translation: AAP98521.1.
PIRiC72063.
F86561.
RefSeqiNP_224766.1. NC_000922.1.
WP_010883208.1. NZ_LN847257.1.

Genome annotation databases

EnsemblBacteriaiAAD18710; AAD18710; CPn_0570.
AAF38053; AAF38053; CP_0179.
AAP98521; AAP98521; CpB0593.
BAA98776; BAA98776; BAA98776.
GeneIDi895322.
KEGGicpa:CP_0179.
cpj:argS.
cpn:CPn0570.
cpt:CpB0593.
PATRICifig|115713.3.peg.635.

Similar proteinsi

Entry informationi

Entry nameiSYR_CHLPN
AccessioniPrimary (citable) accession number: Q9Z7Y3
Secondary accession number(s): Q9JQ78
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: August 30, 2017
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families