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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCPNE115711:GI7B-190-MONOMER.
CPNE115713:GHEY-589-MONOMER.
CPNE138677:GH8N-581-MONOMER.
CPNE182082:GH4N-604-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligase (EC:6.1.1.19)
Alternative name(s):
Arginyl-tRNA synthetase
Short name:
ArgRS
Gene namesi
Name:argS
Ordered Locus Names:CPn_0570, CP_0179, CpB0593
OrganismiChlamydia pneumoniae (Chlamydophila pneumoniae)
Taxonomic identifieri83558 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
ProteomesiUP000000583 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 561561Arginine--tRNA ligasePRO_0000151546Add
BLAST

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi115713.CPn0570.

Structurei

3D structure databases

ProteinModelPortaliQ9Z7Y3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi123 – 13311"HIGH" regionAdd
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247212.
KOiK01887.
OMAiTAMFLLY.
OrthoDBiEOG6JB13C.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9Z7Y3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTLLSILSV ICSQAIAKAF PNLEDWAPEI TPSTKEHFGH YQCNDAMKLA
60 70 80 90 100
RVLKKAPRAI AEAIVAELPQ EPFSLIEIAG AGFINFTFSP VFLNQQLEHF
110 120 130 140 150
KDALKLGFQV SQPKKIIIDF SSPNIAKDMH VGHLRSTIIG DSLARIFSYV
160 170 180 190 200
GHDVLRLNHI GDWGTAFGML ITYLQENPCD YSDLEDLTSL YKKAYVCFTN
210 220 230 240 250
DEEFKKRSQQ NVVALQAKDP QAIAIWEKIC ETSEKAFQKI YDILDIVVEK
260 270 280 290 300
RGESFYNPFL PEIIEDLEKK GLLTVSNDAK CVFHEAFSIP FMVQKSDGGY
310 320 330 340 350
NYATTDLAAM RYRIEEDHAD KIIIVTDLGQ SLHFQLLEAT AIAAGYLQPG
360 370 380 390 400
IFSHVGFGLV LDPQGKKLKT RSGENVKLRE LLDTAIEKAE EALREHRPEL
410 420 430 440 450
TDEAIQERAP VIGINAIKYS DLSSHRTSDY VFSFEKMLRF EGNTAMFLLY
460 470 480 490 500
AYVRIQGIKR RLGISQLSLE GPPEIQEPAE ELLALTLLRF PEALESTIKE
510 520 530 540 550
LCPHFLTDYL YNLTHKFNGF FRDSHIQDSP YAKSRLFLCA LAEQVLATGM
560
HLLGLKTLER L
Length:561
Mass (Da):63,369
Last modified:May 1, 1999 - v1
Checksum:i6386F0FF190C22DB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001363 Genomic DNA. Translation: AAD18710.1.
AE002161 Genomic DNA. Translation: AAF38053.1.
BA000008 Genomic DNA. Translation: BAA98776.1.
AE009440 Genomic DNA. Translation: AAP98521.1.
PIRiC72063.
F86561.
RefSeqiNP_224766.1. NC_000922.1.
NP_300625.1. NC_002491.1.
NP_444730.1. NC_002179.2.
NP_876864.1. NC_005043.1.

Genome annotation databases

EnsemblBacteriaiAAD18710; AAD18710; CPn_0570.
AAF38053; AAF38053; CP_0179.
AAP98521; AAP98521; CpB0593.
BAA98776; BAA98776; BAA98776.
GeneIDi895322.
KEGGicpa:CP0179.
cpj:CPj0570.
cpn:CPn0570.
cpt:CpB0593.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001363 Genomic DNA. Translation: AAD18710.1.
AE002161 Genomic DNA. Translation: AAF38053.1.
BA000008 Genomic DNA. Translation: BAA98776.1.
AE009440 Genomic DNA. Translation: AAP98521.1.
PIRiC72063.
F86561.
RefSeqiNP_224766.1. NC_000922.1.
NP_300625.1. NC_002491.1.
NP_444730.1. NC_002179.2.
NP_876864.1. NC_005043.1.

3D structure databases

ProteinModelPortaliQ9Z7Y3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi115713.CPn0570.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD18710; AAD18710; CPn_0570.
AAF38053; AAF38053; CP_0179.
AAP98521; AAP98521; CpB0593.
BAA98776; BAA98776; BAA98776.
GeneIDi895322.
KEGGicpa:CP0179.
cpj:CPj0570.
cpn:CPn0570.
cpt:CpB0593.

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247212.
KOiK01887.
OMAiTAMFLLY.
OrthoDBiEOG6JB13C.

Enzyme and pathway databases

BioCyciCPNE115711:GI7B-190-MONOMER.
CPNE115713:GHEY-589-MONOMER.
CPNE138677:GH8N-581-MONOMER.
CPNE182082:GH4N-604-MONOMER.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CWL029.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AR39.
  3. "Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA."
    Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K., Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.
    Nucleic Acids Res. 28:2311-2314(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: J138.
  4. "The genome sequence of Chlamydia pneumoniae TW183 and comparison with other Chlamydia strains based on whole genome sequence analysis."
    Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P., Schneider S., Pohl T., Essig A., Marre R., Melchers K.
    Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TW-183.

Entry informationi

Entry nameiSYR_CHLPN
AccessioniPrimary (citable) accession number: Q9Z7Y3
Secondary accession number(s): Q9JQ78
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: June 24, 2015
This is version 112 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.