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Q9Z7Y3 (SYR_CHLPN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 106. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:CPn_0570, CP_0179, CpB0593
OrganismChlamydia pneumoniae (Chlamydophila pneumoniae) [Complete proteome] [HAMAP]
Taxonomic identifier83558 [NCBI]
Taxonomic lineageBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia

Protein attributes

Sequence length561 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 561561Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000151546

Regions

Motif123 – 13311"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q9Z7Y3 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: 6386F0FF190C22DB

FASTA56163,369
        10         20         30         40         50         60 
MSTLLSILSV ICSQAIAKAF PNLEDWAPEI TPSTKEHFGH YQCNDAMKLA RVLKKAPRAI 

        70         80         90        100        110        120 
AEAIVAELPQ EPFSLIEIAG AGFINFTFSP VFLNQQLEHF KDALKLGFQV SQPKKIIIDF 

       130        140        150        160        170        180 
SSPNIAKDMH VGHLRSTIIG DSLARIFSYV GHDVLRLNHI GDWGTAFGML ITYLQENPCD 

       190        200        210        220        230        240 
YSDLEDLTSL YKKAYVCFTN DEEFKKRSQQ NVVALQAKDP QAIAIWEKIC ETSEKAFQKI 

       250        260        270        280        290        300 
YDILDIVVEK RGESFYNPFL PEIIEDLEKK GLLTVSNDAK CVFHEAFSIP FMVQKSDGGY 

       310        320        330        340        350        360 
NYATTDLAAM RYRIEEDHAD KIIIVTDLGQ SLHFQLLEAT AIAAGYLQPG IFSHVGFGLV 

       370        380        390        400        410        420 
LDPQGKKLKT RSGENVKLRE LLDTAIEKAE EALREHRPEL TDEAIQERAP VIGINAIKYS 

       430        440        450        460        470        480 
DLSSHRTSDY VFSFEKMLRF EGNTAMFLLY AYVRIQGIKR RLGISQLSLE GPPEIQEPAE 

       490        500        510        520        530        540 
ELLALTLLRF PEALESTIKE LCPHFLTDYL YNLTHKFNGF FRDSHIQDSP YAKSRLFLCA 

       550        560 
LAEQVLATGM HLLGLKTLER L 

« Hide

References

[1]"Comparative genomes of Chlamydia pneumoniae and C. trachomatis."
Kalman S., Mitchell W.P., Marathe R., Lammel C.J., Fan J., Hyman R.W., Olinger L., Grimwood J., Davis R.W., Stephens R.S.
Nat. Genet. 21:385-389(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CWL029.
[2]"Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39."
Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O., Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S., Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J., Gwinn M.L. expand/collapse author list , Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G., Salzberg S.L., Eisen J.A., Fraser C.M.
Nucleic Acids Res. 28:1397-1406(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AR39.
[3]"Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA."
Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K., Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.
Nucleic Acids Res. 28:2311-2314(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: J138.
[4]"The genome sequence of Chlamydia pneumoniae TW183 and comparison with other Chlamydia strains based on whole genome sequence analysis."
Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P., Schneider S., Pohl T., Essig A., Marre R., Melchers K.
Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: TW-183.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE001363 Genomic DNA. Translation: AAD18710.1.
AE002161 Genomic DNA. Translation: AAF38053.1.
BA000008 Genomic DNA. Translation: BAA98776.1.
AE009440 Genomic DNA. Translation: AAP98521.1.
PIRC72063.
F86561.
RefSeqNP_224766.1. NC_000922.1.
NP_300625.1. NC_002491.1.
NP_444730.1. NC_002179.2.
NP_876864.1. NC_005043.1.

3D structure databases

ProteinModelPortalQ9Z7Y3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING115713.CPn0570.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAD18710; AAD18710; CPn_0570.
AAF38053; AAF38053; CP_0179.
AAP98521; AAP98521; CpB0593.
BAA98776; BAA98776; BAA98776.
GeneID1467271.
895322.
919329.
963786.
KEGGcpa:CP0179.
cpj:CPj0570.
cpn:CPn0570.
cpt:CpB0593.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247212.
KOK01887.
OMAKCFDILG.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycCPNE115711:GI7B-190-MONOMER.
CPNE115713:GHEY-589-MONOMER.
CPNE138677:GH8N-581-MONOMER.
CPNE182082:GH4N-604-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_CHLPN
AccessionPrimary (citable) accession number: Q9Z7Y3
Secondary accession number(s): Q9JQ78
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: May 14, 2014
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries