Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Nucleoside diphosphate kinase

Gene

ndk

Organism
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.UniRule annotation

Catalytic activityi

ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei9ATPUniRule annotation1
Binding sitei57ATPUniRule annotation1
Binding sitei85ATPUniRule annotation1
Binding sitei91ATPUniRule annotation1
Binding sitei102ATPUniRule annotation1
Binding sitei112ATPUniRule annotation1
Active sitei115Pros-phosphohistidine intermediateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processNucleotide metabolism
LigandATP-binding, Magnesium, Metal-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleoside diphosphate kinaseUniRule annotation (EC:2.7.4.6UniRule annotation)
Short name:
NDKUniRule annotation
Short name:
NDP kinaseUniRule annotation
Alternative name(s):
Nucleoside-2-P kinaseUniRule annotation
Gene namesi
Name:ndkUniRule annotation
Ordered Locus Names:CPn_0619, CP_0128, CpB0645
OrganismiChlamydia pneumoniae (Chlamydophila pneumoniae)
Taxonomic identifieri83558 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
Proteomesi
  • UP000000583 Componenti: Chromosome
  • UP000000801 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001369661 – 144Nucleoside diphosphate kinaseAdd BLAST144

Keywords - PTMi

Phosphoprotein

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi182082.CpB0645

Structurei

3D structure databases

ProteinModelPortaliQ9Z7T5
SMRiQ9Z7T5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NDK family.UniRule annotationCurated

Phylogenomic databases

eggNOGiENOG4108UGX Bacteria
COG0105 LUCA
HOGENOMiHOG000224565
KOiK00940
OMAiKIVAMKM
OrthoDBiPOG091H040S

Family and domain databases

Gene3Di3.30.70.141, 1 hit
HAMAPiMF_00451 NDP_kinase, 1 hit
InterProiView protein in InterPro
IPR034907 NDK-like_dom
IPR036850 NDK-like_dom_sf
IPR001564 Nucleoside_diP_kinase
PfamiView protein in Pfam
PF00334 NDK, 1 hit
PRINTSiPR01243 NUCDPKINASE
SMARTiView protein in SMART
SM00562 NDK, 1 hit
SUPFAMiSSF54919 SSF54919, 1 hit

Sequencei

Sequence statusi: Complete.

Q9Z7T5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEQTLSIIKP DSVSKAHIGE ILSIFEQSGL RIAAMKMMHL SQTEAEGFYF
60 70 80 90 100
VHRERPFFQE LVDFMVSGPV VVLVLEGANA VSRNRELMGA TNPAEAASGT
110 120 130 140
IRAKFGESIG VNAVHGSDTL ENAAVEIAYF FSKIEVVNAS KPLV
Length:144
Mass (Da):15,642
Last modified:May 1, 1999 - v1
Checksum:i6811A3A1FD4C8BBF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001363 Genomic DNA Translation: AAD18758.1
AE002161 Genomic DNA Translation: AAF38011.1
BA000008 Genomic DNA Translation: BAA98826.1
AE009440 Genomic DNA Translation: AAP98574.1
PIRiG72056
H86567
RefSeqiNP_224815.1, NC_000922.1
WP_010883257.1, NZ_LN847257.1

Genome annotation databases

EnsemblBacteriaiAAD18758; AAD18758; CPn_0619
AAF38011; AAF38011; CP_0128
AAP98574; AAP98574; CpB0645
BAA98826; BAA98826; BAA98826
GeneIDi895417
KEGGicpa:CP_0128
cpj:ndk
cpn:CPn0619
cpt:CpB0645
PATRICifig|115713.3.peg.689

Similar proteinsi

Entry informationi

Entry nameiNDK_CHLPN
AccessioniPrimary (citable) accession number: Q9Z7T5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: May 1, 1999
Last modified: March 28, 2018
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health