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Q9Z7M5

- PGK_CHLPN

UniProt

Q9Z7M5 - PGK_CHLPN

Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 94 (01 Oct 2014)
      Sequence version 1 (01 May 1999)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei36 – 361SubstrateBy similarity
    Binding sitei119 – 1191SubstrateBy similarity
    Binding sitei154 – 1541SubstrateBy similarity
    Binding sitei207 – 2071ATPBy similarity
    Binding sitei298 – 2981ATP; via carbonyl oxygenBy similarity
    Binding sitei329 – 3291ATPBy similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi356 – 3594ATPBy similarity

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciCPNE115711:GI7B-73-MONOMER.
    CPNE115713:GHEY-706-MONOMER.
    CPNE138677:GH8N-697-MONOMER.
    CPNE182082:GH4N-724-MONOMER.
    UniPathwayiUPA00109; UER00185.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoglycerate kinase (EC:2.7.2.3)
    Gene namesi
    Name:pgk
    Ordered Locus Names:CPn_0679, CP_0068, CpB0706
    OrganismiChlamydia pneumoniae (Chlamydophila pneumoniae)
    Taxonomic identifieri83558 [NCBI]
    Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
    ProteomesiUP000000424: Chromosome, UP000000583: Chromosome, UP000000801: Chromosome, UP000000802: Chromosome

    Subcellular locationi

    Cytoplasm Curated

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 402402Phosphoglycerate kinasePRO_0000145927Add
    BLAST

    Proteomic databases

    PRIDEiQ9Z7M5.

    Interactioni

    Subunit structurei

    Monomer.By similarity

    Protein-protein interaction databases

    STRINGi115713.CPn0679.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9Z7M5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni21 – 233Substrate bindingBy similarity
    Regioni59 – 624Substrate bindingBy similarity

    Sequence similaritiesi

    Belongs to the phosphoglycerate kinase family.Curated

    Phylogenomic databases

    eggNOGiCOG0126.
    HOGENOMiHOG000227107.
    KOiK00927.
    OMAiVAKEFAP.
    OrthoDBiEOG64N9Z0.

    Family and domain databases

    Gene3Di3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPiMF_00145. Phosphoglyc_kinase.
    InterProiIPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view]
    PANTHERiPTHR11406. PTHR11406. 1 hit.
    PfamiPF00162. PGK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000724. Pgk. 1 hit.
    PRINTSiPR00477. PHGLYCKINASE.
    SUPFAMiSSF53748. SSF53748. 1 hit.
    PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9Z7M5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDKLTVQDLS PEEKKVLVRV DFNVPMQDGK ILDDIRIRSA MPTINYLLKK    50
    HAAVILMSHL GRPKGQGFQE EYSLQPVVDV LEGYLGHHVP LAPDCVGEVA 100
    RQAVAQLSPG RVLLLENLRF HIGEEHPEKD PTFAAELSSY GDFYVNDAFG 150
    TSHRKHASVY VVPQAFPGRA AAGLLMEKEL EFLGRHLLTS PKRPFTAILG 200
    GAKISSKIGV IEALLNQVDY LLLAGGMGFT FLQALGKSLG NSLVEKSALD 250
    LARNVLKIAK SRNVTIVLPS DVKAAENLQS KEYSVISIDQ GIPPHLQGFD 300
    IGPRTTEEFI RIINQSATVF WNGPVGVYEV PPFDSGSIAI ANALGNHPSA 350
    VTVVGGGDAA AVVALAGCST KVSHVSTGGG ASLEFLEQGF LPGTEVLSPS 400
    KS 402
    Length:402
    Mass (Da):43,046
    Last modified:May 1, 1999 - v1
    Checksum:i14720238499ECF28
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE001363 Genomic DNA. Translation: AAD18818.1.
    AE002161 Genomic DNA. Translation: AAF37956.1.
    BA000008 Genomic DNA. Translation: BAA98886.1.
    AE009440 Genomic DNA. Translation: AAP98635.1.
    PIRiC72049.
    D86575.
    RefSeqiNP_224875.1. NC_000922.1.
    NP_300735.1. NC_002491.1.
    NP_444620.1. NC_002179.2.
    NP_876978.1. NC_005043.1.

    Genome annotation databases

    EnsemblBacteriaiAAD18818; AAD18818; CPn_0679.
    AAF37956; AAF37956; CP_0068.
    AAP98635; AAP98635; CpB0706.
    BAA98886; BAA98886; BAA98886.
    GeneIDi1467385.
    895421.
    919438.
    963723.
    KEGGicpa:CP0068.
    cpj:CPj0679.
    cpn:CPn0679.
    cpt:CpB0706.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE001363 Genomic DNA. Translation: AAD18818.1 .
    AE002161 Genomic DNA. Translation: AAF37956.1 .
    BA000008 Genomic DNA. Translation: BAA98886.1 .
    AE009440 Genomic DNA. Translation: AAP98635.1 .
    PIRi C72049.
    D86575.
    RefSeqi NP_224875.1. NC_000922.1.
    NP_300735.1. NC_002491.1.
    NP_444620.1. NC_002179.2.
    NP_876978.1. NC_005043.1.

    3D structure databases

    ProteinModelPortali Q9Z7M5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 115713.CPn0679.

    Proteomic databases

    PRIDEi Q9Z7M5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAD18818 ; AAD18818 ; CPn_0679 .
    AAF37956 ; AAF37956 ; CP_0068 .
    AAP98635 ; AAP98635 ; CpB0706 .
    BAA98886 ; BAA98886 ; BAA98886 .
    GeneIDi 1467385.
    895421.
    919438.
    963723.
    KEGGi cpa:CP0068.
    cpj:CPj0679.
    cpn:CPn0679.
    cpt:CpB0706.

    Phylogenomic databases

    eggNOGi COG0126.
    HOGENOMi HOG000227107.
    KOi K00927.
    OMAi VAKEFAP.
    OrthoDBi EOG64N9Z0.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00185 .
    BioCyci CPNE115711:GI7B-73-MONOMER.
    CPNE115713:GHEY-706-MONOMER.
    CPNE138677:GH8N-697-MONOMER.
    CPNE182082:GH4N-724-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPi MF_00145. Phosphoglyc_kinase.
    InterProi IPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view ]
    PANTHERi PTHR11406. PTHR11406. 1 hit.
    Pfami PF00162. PGK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000724. Pgk. 1 hit.
    PRINTSi PR00477. PHGLYCKINASE.
    SUPFAMi SSF53748. SSF53748. 1 hit.
    PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CWL029.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AR39.
    3. "Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA."
      Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K., Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.
      Nucleic Acids Res. 28:2311-2314(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: J138.
    4. "The genome sequence of Chlamydia pneumoniae TW183 and comparison with other Chlamydia strains based on whole genome sequence analysis."
      Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P., Schneider S., Pohl T., Essig A., Marre R., Melchers K.
      Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: TW-183.

    Entry informationi

    Entry nameiPGK_CHLPN
    AccessioniPrimary (citable) accession number: Q9Z7M5
    Secondary accession number(s): Q9JQF8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2000
    Last sequence update: May 1, 1999
    Last modified: October 1, 2014
    This is version 94 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3