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Protein

Ribonuclease P protein component

Gene

rnpA

Organism
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease, RNA-binding
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein componentUniRule annotation (EC:3.1.26.5UniRule annotation)
Short name:
RNase P proteinUniRule annotation
Short name:
RNaseP proteinUniRule annotation
Alternative name(s):
Protein C5UniRule annotation
Gene namesi
Name:rnpAUniRule annotation
Ordered Locus Names:CPn_0934, CP_0927, CpB0967
OrganismiChlamydia pneumoniae (Chlamydophila pneumoniae)
Taxonomic identifieri83558 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
Proteomesi
  • UP000000583 Componenti: Chromosome
  • UP000000801 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001984461 – 139Ribonuclease P protein componentAdd BLAST139

Interactioni

Subunit structurei

Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.UniRule annotation

Protein-protein interaction databases

STRINGi182082.CpB0967

Structurei

3D structure databases

ProteinModelPortaliQ9Z6X2
SMRiQ9Z6X2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RnpA family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0594 LUCA
HOGENOMiHOG000266301
KOiK03536
OMAiREFLEVQ
OrthoDBiPOG091H01XK

Family and domain databases

Gene3Di3.30.230.10, 1 hit
HAMAPiMF_00227 RNase_P, 1 hit
InterProiView protein in InterPro
IPR020568 Ribosomal_S5_D2-typ_fold
IPR014721 Ribosomal_S5_D2-typ_fold_subgr
IPR000100 RNase_P
PANTHERiPTHR33992 PTHR33992, 1 hit
PfamiView protein in Pfam
PF00825 Ribonuclease_P, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD003629 Ribonuclease_P, 1 hit
SUPFAMiSSF54211 SSF54211, 1 hit
TIGRFAMsiTIGR00188 rnpA, 1 hit

Sequencei

Sequence statusi: Complete.

Q9Z6X2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHPLTLPKQS RVLKRKQFLY ITRSGFCCRG SQATFYVVPS RHPGTCRMGI
60 70 80 90 100
TVSKKFGKAH ERNSFKRVVR EVFRHVRHQL PNCQIVVFPK GHKQRPVFSK
110 120 130
LLQDFINQIP EGLHRLGKTK ATTGGECTPK SEKCVTAPR
Length:139
Mass (Da):15,927
Last modified:May 1, 1999 - v1
Checksum:iFEA124BF77FEF23D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001363 Genomic DNA Translation: AAD19072.1
AE002161 Genomic DNA Translation: AAF73717.1
BA000008 Genomic DNA Translation: BAA99142.1
AE009440 Genomic DNA Translation: AAP98897.1
PIRiD86607
H72016
RefSeqiNP_225129.1, NC_000922.1
WP_010883569.1, NZ_LN847257.1

Genome annotation databases

EnsemblBacteriaiAAD19072; AAD19072; CPn_0934
AAF73717; AAF73717; CP_0927
AAP98897; AAP98897; CpB0967
BAA99142; BAA99142; BAA99142
GeneIDi895256
KEGGicpa:CP_0927
cpj:rnpA
cpn:CPn0934
cpt:CpB0967
PATRICifig|115713.3.peg.1022

Similar proteinsi

Entry informationi

Entry nameiRNPA_CHLPN
AccessioniPrimary (citable) accession number: Q9Z6X2
Secondary accession number(s): Q9JQ16
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 1999
Last modified: March 28, 2018
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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