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Q9Z6X2

- RNPA_CHLPN

UniProt

Q9Z6X2 - RNPA_CHLPN

Protein

Ribonuclease P protein component

Gene

rnpA

Organism
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.UniRule annotation

    Catalytic activityi

    Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

    GO - Molecular functioni

    1. ribonuclease P activity Source: UniProtKB-EC
    2. tRNA binding Source: InterPro

    GO - Biological processi

    1. tRNA processing Source: UniProtKB-KW

    Keywords - Molecular functioni

    Endonuclease, Hydrolase, Nuclease

    Keywords - Biological processi

    tRNA processing

    Keywords - Ligandi

    RNA-binding

    Enzyme and pathway databases

    BioCyciCPNE115711:GI7B-957-MONOMER.
    CPNE115713:GHEY-975-MONOMER.
    CPNE138677:GH8N-967-MONOMER.
    CPNE182082:GH4N-1000-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribonuclease P protein componentUniRule annotation (EC:3.1.26.5UniRule annotation)
    Short name:
    RNase P proteinUniRule annotation
    Short name:
    RNaseP proteinUniRule annotation
    Alternative name(s):
    Protein C5UniRule annotation
    Gene namesi
    Name:rnpAUniRule annotation
    Ordered Locus Names:CPn_0934, CP_0927, CpB0967
    OrganismiChlamydia pneumoniae (Chlamydophila pneumoniae)
    Taxonomic identifieri83558 [NCBI]
    Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
    ProteomesiUP000000424: Chromosome, UP000000583: Chromosome, UP000000801: Chromosome, UP000000802: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 139139Ribonuclease P protein componentPRO_0000198446Add
    BLAST

    Interactioni

    Subunit structurei

    Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.UniRule annotation

    Protein-protein interaction databases

    STRINGi115713.CPn0934.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9Z6X2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the RnpA family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0594.
    HOGENOMiHOG000266301.
    KOiK03536.
    OMAiFLYITRS.
    OrthoDBiEOG6XWV8K.

    Family and domain databases

    Gene3Di3.30.230.10. 1 hit.
    HAMAPiMF_00227. RNase_P.
    InterProiIPR020568. Ribosomal_S5_D2-typ_fold.
    IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
    IPR000100. RNase_P.
    [Graphical view]
    PfamiPF00825. Ribonuclease_P. 1 hit.
    [Graphical view]
    ProDomiPD003629. Ribonuclease_P. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SUPFAMiSSF54211. SSF54211. 1 hit.
    TIGRFAMsiTIGR00188. rnpA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q9Z6X2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MHPLTLPKQS RVLKRKQFLY ITRSGFCCRG SQATFYVVPS RHPGTCRMGI    50
    TVSKKFGKAH ERNSFKRVVR EVFRHVRHQL PNCQIVVFPK GHKQRPVFSK 100
    LLQDFINQIP EGLHRLGKTK ATTGGECTPK SEKCVTAPR 139
    Length:139
    Mass (Da):15,927
    Last modified:May 1, 1999 - v1
    Checksum:iFEA124BF77FEF23D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE001363 Genomic DNA. Translation: AAD19072.1.
    AE002161 Genomic DNA. Translation: AAF73717.1.
    BA000008 Genomic DNA. Translation: BAA99142.1.
    AE009440 Genomic DNA. Translation: AAP98897.1.
    PIRiD86607.
    H72016.
    RefSeqiNP_225129.1. NC_000922.1.
    NP_300991.1. NC_002491.1.
    NP_445464.1. NC_002179.2.
    NP_877240.1. NC_005043.1.

    Genome annotation databases

    EnsemblBacteriaiAAD19072; AAD19072; CPn_0934.
    AAF73717; AAF73717; CP_0927.
    AAP98897; AAP98897; CpB0967.
    BAA99142; BAA99142; BAA99142.
    GeneIDi1467647.
    895256.
    919696.
    963388.
    KEGGicpa:CP0927.
    cpj:CPj0934.
    cpn:CPn0934.
    cpt:CpB0967.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE001363 Genomic DNA. Translation: AAD19072.1 .
    AE002161 Genomic DNA. Translation: AAF73717.1 .
    BA000008 Genomic DNA. Translation: BAA99142.1 .
    AE009440 Genomic DNA. Translation: AAP98897.1 .
    PIRi D86607.
    H72016.
    RefSeqi NP_225129.1. NC_000922.1.
    NP_300991.1. NC_002491.1.
    NP_445464.1. NC_002179.2.
    NP_877240.1. NC_005043.1.

    3D structure databases

    ProteinModelPortali Q9Z6X2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 115713.CPn0934.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAD19072 ; AAD19072 ; CPn_0934 .
    AAF73717 ; AAF73717 ; CP_0927 .
    AAP98897 ; AAP98897 ; CpB0967 .
    BAA99142 ; BAA99142 ; BAA99142 .
    GeneIDi 1467647.
    895256.
    919696.
    963388.
    KEGGi cpa:CP0927.
    cpj:CPj0934.
    cpn:CPn0934.
    cpt:CpB0967.

    Phylogenomic databases

    eggNOGi COG0594.
    HOGENOMi HOG000266301.
    KOi K03536.
    OMAi FLYITRS.
    OrthoDBi EOG6XWV8K.

    Enzyme and pathway databases

    BioCyci CPNE115711:GI7B-957-MONOMER.
    CPNE115713:GHEY-975-MONOMER.
    CPNE138677:GH8N-967-MONOMER.
    CPNE182082:GH4N-1000-MONOMER.

    Family and domain databases

    Gene3Di 3.30.230.10. 1 hit.
    HAMAPi MF_00227. RNase_P.
    InterProi IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
    IPR000100. RNase_P.
    [Graphical view ]
    Pfami PF00825. Ribonuclease_P. 1 hit.
    [Graphical view ]
    ProDomi PD003629. Ribonuclease_P. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SUPFAMi SSF54211. SSF54211. 1 hit.
    TIGRFAMsi TIGR00188. rnpA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CWL029.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AR39.
    3. "Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA."
      Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K., Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.
      Nucleic Acids Res. 28:2311-2314(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: J138.
    4. "The genome sequence of Chlamydia pneumoniae TW183 and comparison with other Chlamydia strains based on whole genome sequence analysis."
      Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P., Schneider S., Pohl T., Essig A., Marre R., Melchers K.
      Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: TW-183.

    Entry informationi

    Entry nameiRNPA_CHLPN
    AccessioniPrimary (citable) accession number: Q9Z6X2
    Secondary accession number(s): Q9JQ16
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 2000
    Last sequence update: May 1, 1999
    Last modified: October 1, 2014
    This is version 94 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3