Reviewed, UniProtKB/Swiss-Prot Q9Z6V8 (GLGA_CHLPN)

Names and origin

Protein names

Recommended name:
    Glycogen synthase
    EC=2.4.1.21
Alternative name(s):
    Starch [bacterial glycogen] synthase

Gene names

Name:	glgA
Ordered Locus Names:	CPn_0948, CP_0911, CpB0983

Organism

Chlamydia pneumoniae (Chlamydophila pneumoniae) [Complete proteome] [HAMAP]

Taxonomic identifier

83558 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydophila

Protein attributes

Sequence length	476 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Synthesizes alpha-1,4-glucan chains using ADP-glucose. HAMAP MF_00484
Catalytic activity	ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP MF_00484
Pathway	Glycan biosynthesis; glycogen biosynthesis. HAMAP MF_00484
Sequence similarities	Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
Biological process	Glycogen biosynthesis
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycogen biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	starch synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 476	476	Glycogen synthase HAMAP MF_00484		PRO_0000188604
Sites
	Binding site	15	1	ADP-glucose By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9Z6V8-1 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: 61C9262256E2A7FB	FASTA	476	53,146
	10 20 30 40 50 60 MRIVQVAVEF TPIVKVGGLG DAVASLSKEL AKQNDVEVLL PHYPLISKFS SSQVLSERSF 70 80 90 100 110 120 YYEFLGKQQA SAISYSYEGL TLTIITLDSQ IELFSTTSVY SENNVVRFSA FAAAAAAYLQ 130 140 150 160 170 180 EADPADIVHL HDWHVGLLAG LLKNPLNPVH SKIVFTIHNF GYRGYCSTQL LAASQIDDFH 190 200 210 220 230 240 LSHYQLFRDP QTSVLMKGAL YCSDYITTVS LTYVQEIIND YSDYELHDAI LARNSVFSGI 250 260 270 280 290 300 INGIDEDVWN PKTDPALAVQ YDASLLSEPD VLFTKKEENR AVLYEKLGIS SDYFPLICVI 310 320 330 340 350 360 SRIVEEKGPE FMKEIILHAM EHSYAFILIG TSQNEVLLNE FRNLQDCLAS SPNIRLILDF 370 380 390 400 410 420 NDPLARLTYA AADMICIPSH REACGLTQLI AMRYGTVPLV RKTGGLADTV IPGVNGFTFF 430 440 450 460 470 DTNNFNEFRA MLSNAVTTYR QEPDVWLNLI ESGMLRASGL DAMAKHYVNL YQSLLS

References

[1]	"Comparative genomes of Chlamydia pneumoniae and C. trachomatis." Kalman S., Mitchell W.P., Marathe R., Lammel C.J., Fan J., Hyman R.W., Olinger L., Grimwood J., Davis R.W., Stephens R.S. Nat. Genet. 21:385-389(1999) [PubMed: 10192388] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CWL029.
[2]	"Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39." Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O., Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S., Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J., Gwinn M.L. , Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G., Salzberg S.L., Eisen J.A., Fraser C.M. Nucleic Acids Res. 28:1397-1406(2000) [PubMed: 10684935] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AR39.
[3]	"Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA." Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K., Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T. Nucleic Acids Res. 28:2311-2314(2000) [PubMed: 10871362] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: J138.
[4]	"The genome sequence of Chlamydia pneumoniae TW183 and comparison with other Chlamydia strains based on whole genome sequence analysis." Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P., Schneider S., Pohl T., Essig A., Marre R., Melchers K. Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TW-183.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE001363 Genomic DNA. Translation: AAD19086.1. AE002161 Genomic DNA. Translation: AAF38696.1. BA000008 Genomic DNA. Translation: BAA99156.1. AE009440 Genomic DNA. Translation: AAP98913.1.
PIR	B86609. C72016.
RefSeq	NP_225143.1. NP_301005.1. NP_445448.1. NP_877256.1.
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	GT5. Glycosyltransferase Family 5.
Genome annotation databases
GeneID	1467663. 895529. 919710. 963368.
GenomeReviews	Gene locus CPn_0948 in contig AE001363_GR. Gene locus CP_0911 in contig AE002161_GR. Gene locus CpB0983 in contig AE009440_GR. Gene locus glgA in contig BA000008_GR.
KEGG	cpa:CP0911. cpn:CPn0948. cpt:CpB0983.
TIGR	CP_0911.
Phylogenomic databases
HOGENOM	Q9Z6V8.
OMA	RMFAGSD.
Enzyme and pathway databases
BioCyc	CPNE115711:CP_0911-MON. CPNE115713:CPN0948-MON. CPNE138677:CPJ0948-MON. CPNE182082:CPB0983-MON.
BRENDA	2.4.1.21. 264832.
Family and domain databases
HAMAP	MF_00484. [Tree]
InterPro	IPR011835. GlgA. IPR001296. Glyco_trans_1. IPR013534. Glyco_transf_5. [Graphical view]
Pfam	PF08323. Glyco_transf_5. 1 hit. PF00534. Glycos_transf_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR02095. glgA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLGA_CHLPN

Accession

Primary (citable) accession number: Q9Z6V8

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 16, 2001
Last sequence update:	May 1, 1999
Last modified:	November 3, 2009
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)