SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9Z6S3

- TRMB_CHLPN

UniProt

Q9Z6S3 - TRMB_CHLPN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

tRNA (guanine-N(7)-)-methyltransferase

Gene
trmB, CPn_0986, CP_0869, CPj0986, CpB1023
Organism
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei54 – 541S-adenosyl-L-methionine By similarity
Binding sitei79 – 791S-adenosyl-L-methionine By similarity
Active sitei129 – 1291 By similarity
Binding sitei129 – 1291S-adenosyl-L-methionine By similarity
Binding sitei133 – 1331Substrate By similarity
Binding sitei165 – 1651Substrate By similarity

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciCPNE115711:GI7B-898-MONOMER.
CPNE115713:GHEY-1028-MONOMER.
CPNE138677:GH8N-1018-MONOMER.
CPNE182082:GH4N-1056-MONOMER.
UniPathwayiUPA00989.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA (guanine-N(7)-)-methyltransferase (EC:2.1.1.33)
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferase
tRNA(m7G46)-methyltransferase
Gene namesi
Name:trmB
Ordered Locus Names:CPn_0986, CP_0869, CPj0986, CpB1023
OrganismiChlamydia pneumoniae (Chlamydophila pneumoniae)
Taxonomic identifieri83558 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
ProteomesiUP000000424: Chromosome, UP000000583: Chromosome, UP000000801: Chromosome, UP000000802: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 224224tRNA (guanine-N(7)-)-methyltransferaseUniRule annotationPRO_0000171316Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi115713.CPn0986.

Structurei

3D structure databases

ProteinModelPortaliQ9Z6S3.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0220.
HOGENOMiHOG000034940.
KOiK03439.
OMAiIVELAMN.
OrthoDBiEOG6K6VBC.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01057. tRNA_methyltr_TrmB.
InterProiIPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PfamiPF02390. Methyltransf_4. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9Z6S3-1 [UniParc]FASTAAdd to Basket

« Hide

MKPQDLSPPF LWKERRPCIQ DGVLYVPRHY FEHQNFSTSY HQEFFQNHTS    50
IACELCSGNG DWVVAQAQKD PQVLWIAVEQ RFDRVRKIWS KMINHQIQNL 100
RIVCGTAETF FQYYVPDQFL QRLVVNFPDP WPKMRHRKHR LLQPSFVQEI 150
SRSLQDSAVF ALATDDKTYL LESIEALQTH LAPRMETPYY IKMTDTYGNS 200
WFENLWRTKG QEIFYTEFIK KAGI 224
Length:224
Mass (Da):26,729
Last modified:May 1, 1999 - v1
Checksum:i60C969E22FB7F028
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE001363 Genomic DNA. Translation: AAD19123.1.
AE002161 Genomic DNA. Translation: AAF38658.1.
BA000008 Genomic DNA. Translation: BAA99193.1.
AE009440 Genomic DNA. Translation: AAP98952.1.
PIRiC72010.
G86613.
RefSeqiNP_225180.1. NC_000922.1.
NP_301041.1. NC_002491.1.
NP_445407.1. NC_002179.2.
NP_877295.1. NC_005043.1.

Genome annotation databases

EnsemblBacteriaiAAD19123; AAD19123; CPn_0986.
AAF38658; AAF38658; CP_0869.
AAP98952; AAP98952; CpB1023.
BAA99193; BAA99193; BAA99193.
GeneIDi1467702.
895603.
919748.
963320.
KEGGicpa:CP0869.
cpj:CPj0986.
cpn:CPn0986.
cpt:CpB1023.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE001363 Genomic DNA. Translation: AAD19123.1 .
AE002161 Genomic DNA. Translation: AAF38658.1 .
BA000008 Genomic DNA. Translation: BAA99193.1 .
AE009440 Genomic DNA. Translation: AAP98952.1 .
PIRi C72010.
G86613.
RefSeqi NP_225180.1. NC_000922.1.
NP_301041.1. NC_002491.1.
NP_445407.1. NC_002179.2.
NP_877295.1. NC_005043.1.

3D structure databases

ProteinModelPortali Q9Z6S3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 115713.CPn0986.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAD19123 ; AAD19123 ; CPn_0986 .
AAF38658 ; AAF38658 ; CP_0869 .
AAP98952 ; AAP98952 ; CpB1023 .
BAA99193 ; BAA99193 ; BAA99193 .
GeneIDi 1467702.
895603.
919748.
963320.
KEGGi cpa:CP0869.
cpj:CPj0986.
cpn:CPn0986.
cpt:CpB1023.

Phylogenomic databases

eggNOGi COG0220.
HOGENOMi HOG000034940.
KOi K03439.
OMAi IVELAMN.
OrthoDBi EOG6K6VBC.

Enzyme and pathway databases

UniPathwayi UPA00989 .
BioCyci CPNE115711:GI7B-898-MONOMER.
CPNE115713:GHEY-1028-MONOMER.
CPNE138677:GH8N-1018-MONOMER.
CPNE182082:GH4N-1056-MONOMER.

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
HAMAPi MF_01057. tRNA_methyltr_TrmB.
InterProi IPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view ]
Pfami PF02390. Methyltransf_4. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CWL029.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AR39.
  3. "Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA."
    Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K., Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.
    Nucleic Acids Res. 28:2311-2314(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: J138.
  4. "The genome sequence of Chlamydia pneumoniae TW183 and comparison with other Chlamydia strains based on whole genome sequence analysis."
    Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P., Schneider S., Pohl T., Essig A., Marre R., Melchers K.
    Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TW-183.

Entry informationi

Entry nameiTRMB_CHLPN
AccessioniPrimary (citable) accession number: Q9Z6S3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: May 1, 1999
Last modified: June 11, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi