Reviewed, UniProtKB/Swiss-Prot Q9Z6C1 (CDH_ENTCL)

Names and origin

Protein names

Recommended name:
    CDP-diacylglycerol pyrophosphatase
    EC=3.6.1.26
Alternative name(s):
    CDP-diacylglycerol phosphatidylhydrolase
    CDP-diglyceride hydrolase

Gene names

Name:

cdh

Organism

Enterobacter cloacae

Taxonomic identifier

550 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Enterobacter › Enterobacter cloacae complex

Protein attributes

Sequence length	247 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	CDP-diacylglycerol + H2O = CMP + phosphatidate. HAMAP MF_00319
Pathway	Phospholipid metabolism; CDP-diacylglycerol degradation; phosphatidate from CDP-diacylglycerol: step 1/1. HAMAP MF_00319
Subcellular location	Cell inner membrane; Single-pass membrane protein By similarity.
Sequence similarities	Belongs to the cdh family.

Ontologies

Keywords
Biological process	Phospholipid biosynthesis
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane
Molecular function	Hydrolase
Gene Ontology (GO)
Biological process	phospholipid biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	CDP-diacylglycerol diphosphatase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 247	247	CDP-diacylglycerol pyrophosphatase HAMAP MF_00319		PRO_0000198576
Regions
	Transmembrane	4 – 24	21	Potential

Sequences

	Sequence		Length	Mass (Da)
	Q9Z6C1-1 [UniParc]. Last modified February 21, 2001. Version 2. Checksum: C73E28CC9A36E4F7	FASTA	247	27,718
	10 20 30 40 50 60 MKKIILLLLI VIALAAGGVY WMKAGNPNAL RHIVLDQCVP NQIQNRNPAP CAQVKTDAGY 70 80 90 100 110 120 VVFKDRNGPL QYLLMPTYRI NGTESPLLTE AHTPNFFWLA WQSRSFMTLK HGSEVPDSAI 130 140 150 160 170 180 SLTINSPTGR TQNHFHIHIS CLRPDVREKL NAAQGEISTQ WLPLPGGLEG HEYLARRVTE 190 200 210 220 230 240 NELVQRSPFM MLAEELPEAR DHMGRFALAM AQQSDGSFVL LATERNLLTL NRASAEELQD HQCTILK

References

[1]

"Role of pfkA and general carbohydrate catabolism in seed colonization by Enterobacter cloacae." Roberts D.P., Dery P.D., Yucel I., Buyer J., Holtman M.A., Kobayashi D.Y. Appl. Environ. Microbiol. 65:2513-2519(1999) [PubMed: 10347036] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: A-11 / 501R3.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF098509 Genomic DNA. Translation: AAD16181.1. Different initiation.
3D structure databases
ModBase	Search...
Enzyme and pathway databases
BRENDA	3.6.1.26. 1834.
Family and domain databases
HAMAP	MF_00319. [Tree]
InterPro	IPR003763. CDP-diacylglyc_Pase_bac. IPR015993. CDP-diacylglyc_Pase_proteobac. [Graphical view]
Pfam	PF02611. CDH. 1 hit. [Graphical view]
PIRSF	PIRSF001273. CDH. 1 hit.
TIGRFAMs	TIGR00672. cdh. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CDH_ENTCL

Accession

Primary (citable) accession number: Q9Z6C1

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 21, 2001
Last sequence update:	February 21, 2001
Last modified:	June 16, 2009
This is version 43 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)