ID   Q9Z649_TATCI            Unreviewed;       246 AA.
AC   Q9Z649;
DT   01-MAY-1999, integrated into UniProtKB/TrEMBL.
DT   01-MAY-1999, sequence version 1.
DT   24-JAN-2024, entry version 51.
DE   RecName: Full=Heme exporter protein C {ECO:0000256|ARBA:ARBA00016463, ECO:0000256|RuleBase:RU364092};
DE   AltName: Full=Cytochrome c-type biogenesis protein {ECO:0000256|RuleBase:RU364092};
GN   Name=ccmC {ECO:0000256|RuleBase:RU364092,
GN   ECO:0000313|EMBL:AAD19539.1};
OS   Tatumella citrea (Pantoea citrea).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Tatumella.
OX   NCBI_TaxID=53336 {ECO:0000313|EMBL:AAD19539.1};
RN   [1] {ECO:0000313|EMBL:AAD19539.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=1056R {ECO:0000313|EMBL:AAD19539.1};
RX   PubMed=10735866; DOI=10.1128/JB.182.8.2230-2237.2000;
RA   Pujol C.J., Kado C.I.;
RT   "Genetic and biochemical characterization of the pathway in Pantoea citrea
RT   leading to pink disease of pineapple.";
RL   J. Bacteriol. 182:2230-2237(2000).
CC   -!- FUNCTION: Required for the export of heme to the periplasm for the
CC       biogenesis of c-type cytochromes. {ECO:0000256|ARBA:ARBA00002442,
CC       ECO:0000256|RuleBase:RU364092}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000256|RuleBase:RU364092}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the CcmC/CycZ/HelC family.
CC       {ECO:0000256|ARBA:ARBA00005840, ECO:0000256|RuleBase:RU364092}.
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DR   EMBL; AF103874; AAD19539.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9Z649; -.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0015232; F:heme transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
DR   InterPro; IPR002541; Cyt_c_assembly.
DR   InterPro; IPR003557; Cyt_c_biogenesis_CcmC.
DR   InterPro; IPR045062; Cyt_c_biogenesis_CcsA/CcmC.
DR   NCBIfam; TIGR01191; ccmC; 1.
DR   PANTHER; PTHR30071:SF17; CYTOCHROME C ASSEMBLY PROTEIN-RELATED; 1.
DR   PANTHER; PTHR30071; HEME EXPORTER PROTEIN C; 1.
DR   Pfam; PF01578; Cytochrom_C_asm; 1.
DR   PRINTS; PR01386; CCMCBIOGNSIS.
PE   3: Inferred from homology;
KW   Cell inner membrane {ECO:0000256|RuleBase:RU364092};
KW   Cell membrane {ECO:0000256|RuleBase:RU364092};
KW   Cytochrome c-type biogenesis {ECO:0000256|RuleBase:RU364092};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364092};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU364092};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU364092}; Transport {ECO:0000256|RuleBase:RU364092}.
FT   TRANSMEM        21..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364092"
FT   TRANSMEM        63..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364092"
FT   TRANSMEM        91..115
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364092"
FT   TRANSMEM        127..146
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364092"
FT   TRANSMEM        158..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364092"
FT   TRANSMEM        203..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364092"
FT   DOMAIN          6..184
FT                   /note="Cytochrome c assembly protein"
FT                   /evidence="ECO:0000259|Pfam:PF01578"
SQ   SEQUENCE   246 AA;  27879 MW;  3FDF664C86E57523 CRC64;
     MWKWLHQLAK PERLYNICGR FIPWVSLAAL ITLLLGWIWG FGYAPPDYQQ GDSYRIMYIH
     VPAAMWSMGV YASMAIAAFI GLVWQMKMSD LVASAMAPVG AVFTFIALVT GSAWGKPMWG
     TWWVWDARLT SELVLLFIYM GVITLYNAFD DRRVAGRAAG ILILVGVVNL PIIHYSVQWW
     NTLHQGSSGI LQQDIAPSMR TPLRWAILGY LLVFISLTLM RLRNLILVTE RNRPWVSAIA
     NKGRTS
//