Q9Z615 (FENR_BUCAP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ferredoxin--NADP reductase
Short name=FNR
EC=1.18.1.2

Alternative name(s):
Flavodoxin reductase
Short name=FLDR
Short name=FLXR

Gene names

Name:	fpr
Ordered Locus Names:	BUsg_560

Organism

Buchnera aphidicola subsp. Schizaphis graminum (strain Sg) [Complete proteome] [HAMAP]

Taxonomic identifier

198804 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera › Buchnera aphidicola › Buchnera aphidicola (Schizaphis graminum)

Protein attributes

Sequence length	257 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Transports electrons between flavodoxin or ferredoxin and NADPH By similarity.
Catalytic activity	2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH.
Cofactor	FAD By similarity.
Sequence similarities	Belongs to the ferredoxin--NADP reductase type 1 family. Contains 1 FAD-binding FR-type domain.

Ontologies

Keywords
Ligand	FAD Flavoprotein NADP
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	ferredoxin-NADP+ reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 257	257	Ferredoxin--NADP reductase		PRO_0000167641
Regions
	Domain	2 – 110	109	FAD-binding FR-type
	Nucleotide binding	59 – 62	4	FAD By similarity
	Nucleotide binding	82 – 85	4	FAD By similarity
	Nucleotide binding	152 – 153	2	NADP By similarity
	Nucleotide binding	182 – 183	2	NADP By similarity
	Nucleotide binding	222 – 223	2	NADP By similarity
Sites
	Binding site	62	1	NADP By similarity
	Binding site	125	1	FAD By similarity
	Binding site	125	1	NADP; via amide nitrogen By similarity
	Binding site	254	1	NADP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9Z615 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: F1BF24F2D5FAA07B	FASTA	257	30,079
	10 20 30 40 50 60 MNPWINANVL KVHKWTQNLF SLILNAEIAP FQAGQFTKLA LNEENINFSN NVKKKKIQRA 70 80 90 100 110 120 YSFVNAPSNK NLEIYIVRIL NGKLSNLLYN LKSGDNLFIK EKSFGFFTLD EIPNCKTLWM 130 140 150 160 170 180 FATGTGIGPY CSILQEYKNI NRFKNIILIH AVRYQNELTY LPLMKQLYKS YNGKLKIETI 190 200 210 220 230 240 VSREKNHNSL YGRIPLLLQN QILEKKIGLK INRNDSHVML CGNPAMVKDT YLFLQKDRCM 250 QKNLRRKHGH ITMENYW

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Buchnera plasmid-associated trpEG probably originated from a chromosomal location between hslU and fpr." Clark M.A., Baumann P., Moran M.A. Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"50 million years of genomic stasis in endosymbiotic bacteria." Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E. Science 296:2376-2379(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Sg.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF108665 Genomic DNA. Translation: AAD19635.1. AE013218 Genomic DNA. Translation: AAM68098.1.
RefSeq	NP_660887.1. NC_004061.1.
3D structure databases
ProteinModelPortal	Q9Z615.
SMR	Q9Z615. Positions 3-257.
ModBase	Search...
Protein-protein interaction databases
STRING	198804.BUsg560.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAM68098; AAM68098; BUsg_560.
GeneID	1005631.
KEGG	bas:BUsg560.
PATRIC	21248006. VBIBucAph100086_0594.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1018.
KO	K00528.
OMA	RFKNIVL.
ProtClustDB	CLSK552879.
Enzyme and pathway databases
BioCyc	BAPH198804:GHMG-600-MONOMER.
Family and domain databases
InterPro	IPR017927. Fd_Rdtase_FAD-bd. IPR008333. OxRdtase_FAD-bd_dom. IPR001433. OxRdtase_FAD/NAD-bd. IPR017938. Riboflavin_synthase-like_b-brl. [Graphical view]
Pfam	PF00970. FAD_binding_6. 1 hit. PF00175. NAD_binding_1. 1 hit. [Graphical view]
SUPFAM	SSF63380. Riboflavin_synthase_like_b-brl. 1 hit.
PROSITE	PS51384. FAD_FR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

FENR_BUCAP

Accession

Primary (citable) accession number: Q9Z615

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	May 1, 1999
Last modified:	May 1, 2013
This is version 83 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program