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Q9Z523 (G6PI2_STRCO) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 85. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase 2

Short name=GPI 2
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase 2
Short name=PGI 2
Phosphohexose isomerase 2
Short name=PHI 2
Gene names
Name:pgi2
Ordered Locus Names:SCO1942
ORF Names:SCC54.02c
OrganismStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) [Reference proteome] [HAMAP]
Taxonomic identifier100226 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomycesStreptomyces albidoflavus group

Protein attributes

Sequence length551 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 551551Glucose-6-phosphate isomerase 2 HAMAP-Rule MF_00473
PRO_0000180750

Sites

Active site3591Proton donor By similarity
Active site3901 By similarity
Active site5141 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9Z523 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: 631BD4A76EB34643

FASTA55160,570
        10         20         30         40         50         60 
MNADGRTRLH QTPEWAALVK HREQLGEVRL REMFAADPGR GTGWTLRVGD LHVDYSKHLV 

        70         80         90        100        110        120 
TDETLALLQE LAAATGVSGL RDAMFRGERI NITEDRAVLH TALRAPRDAV IEVDGENVVP 

       130        140        150        160        170        180 
QVHAVLDKMA GFADRVRTGE WTGHTGRRIR NVVNIGIGGS DLGPAMAYEA LRAFTDRSLT 

       190        200        210        220        230        240 
LRFVSNVDGA DLHEAVRDLD PAETLFIIAS KTFTTIETIT NATSARSWLL AGLGGDEKAV 

       250        260        270        280        290        300 
AKHFVALSTN AEKVADFGID TANMFEFWDW VGGRYSFDSA IGLSLMIAIG PDRFREMLDG 

       310        320        330        340        350        360 
FHLVDEHFRT APAESNVPLL MGLLGVWYGS FLGAQSHAVL PYSHYLSKFT AYLQQLDMES 

       370        380        390        400        410        420 
NGKSVDREGK PVQWQTGPVV WGTPGTNGQH AYYQLIHQGT KLIPADFIGF ARPVDELSEE 

       430        440        450        460        470        480 
LKSQHDLLMA NFFAQTQALA FGKTPDEVRA EGVPEELVPH KTFPGDHPTT TILARELTPS 

       490        500        510        520        530        540 
VLGQLVALYE HKVFVQGAIW NIDSFDQWGV ELGKVLAKRV EPALTEGADV PGLDPSTGAL 

       550 
VAAYRELRGR R 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL939110 Genomic DNA. Translation: CAB38132.1.
PIRT36015.
RefSeqNP_626206.1. NC_003888.3.

3D structure databases

ProteinModelPortalQ9Z523.
SMRQ9Z523. Positions 2-548.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING100226.SCO1942.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAB38132; CAB38132; CAB38132.
GeneID1097376.
KEGGsco:SCO1942.
PATRIC23733518. VBIStrCoe124346_1969.

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261371.
KOK01810.
OMAHKILAAN.
OrthoDBEOG64R61J.
PhylomeDBQ9Z523.

Enzyme and pathway databases

UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI2_STRCO
AccessionPrimary (citable) accession number: Q9Z523
Entry history
Integrated into UniProtKB/Swiss-Prot: November 2, 2001
Last sequence update: May 1, 1999
Last modified: June 11, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways