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Q9Z523

- G6PI2_STRCO

UniProt

Q9Z523 - G6PI2_STRCO

Protein

Glucose-6-phosphate isomerase 2

Gene

pgi2

Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 86 (01 Oct 2014)
      Sequence version 1 (01 May 1999)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei359 – 3591Proton donorBy similarity
    Active sitei390 – 3901By similarity
    Active sitei514 – 5141By similarity

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    UniPathwayiUPA00109; UER00181.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomerase 2 (EC:5.3.1.9)
    Short name:
    GPI 2
    Alternative name(s):
    Phosphoglucose isomerase 2
    Short name:
    PGI 2
    Phosphohexose isomerase 2
    Short name:
    PHI 2
    Gene namesi
    Name:pgi2
    Ordered Locus Names:SCO1942
    ORF Names:SCC54.02c
    OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
    Taxonomic identifieri100226 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
    ProteomesiUP000001973: Chromosome

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 551551Glucose-6-phosphate isomerase 2PRO_0000180750Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi100226.SCO1942.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9Z523.
    SMRiQ9Z523. Positions 2-548.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.Curated

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000261371.
    KOiK01810.
    OMAiHKILAAN.
    OrthoDBiEOG64R61J.
    PhylomeDBiQ9Z523.

    Family and domain databases

    Gene3Di1.10.1390.10. 1 hit.
    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9Z523-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNADGRTRLH QTPEWAALVK HREQLGEVRL REMFAADPGR GTGWTLRVGD    50
    LHVDYSKHLV TDETLALLQE LAAATGVSGL RDAMFRGERI NITEDRAVLH 100
    TALRAPRDAV IEVDGENVVP QVHAVLDKMA GFADRVRTGE WTGHTGRRIR 150
    NVVNIGIGGS DLGPAMAYEA LRAFTDRSLT LRFVSNVDGA DLHEAVRDLD 200
    PAETLFIIAS KTFTTIETIT NATSARSWLL AGLGGDEKAV AKHFVALSTN 250
    AEKVADFGID TANMFEFWDW VGGRYSFDSA IGLSLMIAIG PDRFREMLDG 300
    FHLVDEHFRT APAESNVPLL MGLLGVWYGS FLGAQSHAVL PYSHYLSKFT 350
    AYLQQLDMES NGKSVDREGK PVQWQTGPVV WGTPGTNGQH AYYQLIHQGT 400
    KLIPADFIGF ARPVDELSEE LKSQHDLLMA NFFAQTQALA FGKTPDEVRA 450
    EGVPEELVPH KTFPGDHPTT TILARELTPS VLGQLVALYE HKVFVQGAIW 500
    NIDSFDQWGV ELGKVLAKRV EPALTEGADV PGLDPSTGAL VAAYRELRGR 550
    R 551
    Length:551
    Mass (Da):60,570
    Last modified:May 1, 1999 - v1
    Checksum:i631BD4A76EB34643
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL939110 Genomic DNA. Translation: CAB38132.1.
    PIRiT36015.
    RefSeqiNP_626206.1. NC_003888.3.

    Genome annotation databases

    EnsemblBacteriaiCAB38132; CAB38132; CAB38132.
    GeneIDi1097376.
    KEGGisco:SCO1942.
    PATRICi23733518. VBIStrCoe124346_1969.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL939110 Genomic DNA. Translation: CAB38132.1 .
    PIRi T36015.
    RefSeqi NP_626206.1. NC_003888.3.

    3D structure databases

    ProteinModelPortali Q9Z523.
    SMRi Q9Z523. Positions 2-548.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 100226.SCO1942.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAB38132 ; CAB38132 ; CAB38132 .
    GeneIDi 1097376.
    KEGGi sco:SCO1942.
    PATRICi 23733518. VBIStrCoe124346_1969.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000261371.
    KOi K01810.
    OMAi HKILAAN.
    OrthoDBi EOG64R61J.
    PhylomeDBi Q9Z523.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .

    Family and domain databases

    Gene3Di 1.10.1390.10. 1 hit.
    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-471 / A3(2) / M145.

    Entry informationi

    Entry nameiG6PI2_STRCO
    AccessioniPrimary (citable) accession number: Q9Z523
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 2, 2001
    Last sequence update: May 1, 1999
    Last modified: October 1, 2014
    This is version 86 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3