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Q9Z519 (PGK_STRCO) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 88. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:SCO1946
ORF Names:SCC54.06c
OrganismStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) [Reference proteome] [HAMAP]
Taxonomic identifier100226 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

Protein attributes

Sequence length403 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 403403Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_0000146013

Regions

Nucleotide binding359 – 3624ATP By similarity
Region22 – 243Substrate binding By similarity
Region60 – 634Substrate binding By similarity

Sites

Binding site371Substrate By similarity
Binding site1191Substrate By similarity
Binding site1561Substrate By similarity
Binding site2061ATP By similarity
Binding site3021ATP; via carbonyl oxygen By similarity
Binding site3331ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9Z519 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: C42094E7C6221FE5

FASTA40341,765
        10         20         30         40         50         60 
MKTIDELLSE GVAGKRVFVR ADLNVPLDGT TITDDGRIRA VVPTVKALAD AGARVIVASH 

        70         80         90        100        110        120 
LGRPKGAPDP AFSLAPAAAR LGELLGADVA FAEDTVGSSA EAVVTGLADG GVAVIENLRF 

       130        140        150        160        170        180 
NAGETSKDDA ERAAFADKLA GLADVYVGDG FGAVHRKHAS VFDLPKRLPH YAGYLIATEV 

       190        200        210        220        230        240 
GVLKKLTDEV KRPYVVALGG AKVSDKLAVI DQLLGKADRL LIGGGMAYTF LKAKGYEVGI 

       250        260        270        280        290        300 
SLLQEDQIPA VKEYIERAEK NGVELVLPVD VLVAPEFPDL KTKAPANPTT VAADAIPADQ 

       310        320        330        340        350        360 
EGLDIGPETR KLYASKLADA GTVFWNGPMG VFEHPDYAEG TKAVAQALVD APGFTVVGGG 

       370        380        390        400 
DSAAAVRTLG FDENAFGHIS TGGGASLEYL EGKTLPGLAA LED 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL939110 Genomic DNA. Translation: CAB38136.1.
PIRT36019.
RefSeqNP_626210.1. NC_003888.3.

3D structure databases

ProteinModelPortalQ9Z519.
SMRQ9Z519. Positions 1-403.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING100226.SCO1946.

Proteomic databases

PRIDEQ9Z519.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAB38136; CAB38136; CAB38136.
GeneID1097380.
KEGGsco:SCO1946.
PATRIC23733526. VBIStrCoe124346_1973.

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227107.
KOK00927.
OMADMIFDIG.
OrthoDBEOG64N9Z0.
PhylomeDBQ9Z519.
ProtClustDBPRK00073.

Enzyme and pathway databases

UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_STRCO
AccessionPrimary (citable) accession number: Q9Z519
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: April 16, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways