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Q9Z519

- PGK_STRCO

UniProt

Q9Z519 - PGK_STRCO

Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 91 (01 Oct 2014)
      Sequence version 1 (01 May 1999)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei37 – 371SubstrateBy similarity
    Binding sitei119 – 1191SubstrateBy similarity
    Binding sitei156 – 1561SubstrateBy similarity
    Binding sitei206 – 2061ATPBy similarity
    Binding sitei302 – 3021ATP; via carbonyl oxygenBy similarity
    Binding sitei333 – 3331ATPBy similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi359 – 3624ATPBy similarity

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    UniPathwayiUPA00109; UER00185.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoglycerate kinase (EC:2.7.2.3)
    Gene namesi
    Name:pgk
    Ordered Locus Names:SCO1946
    ORF Names:SCC54.06c
    OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
    Taxonomic identifieri100226 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
    ProteomesiUP000001973: Chromosome

    Subcellular locationi

    Cytoplasm Curated

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 403403Phosphoglycerate kinasePRO_0000146013Add
    BLAST

    Proteomic databases

    PRIDEiQ9Z519.

    Interactioni

    Subunit structurei

    Monomer.By similarity

    Protein-protein interaction databases

    STRINGi100226.SCO1946.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9Z519.
    SMRiQ9Z519. Positions 1-403.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni22 – 243Substrate bindingBy similarity
    Regioni60 – 634Substrate bindingBy similarity

    Sequence similaritiesi

    Belongs to the phosphoglycerate kinase family.Curated

    Phylogenomic databases

    eggNOGiCOG0126.
    HOGENOMiHOG000227107.
    KOiK00927.
    OMAiAGHPVGK.
    OrthoDBiEOG64N9Z0.
    PhylomeDBiQ9Z519.

    Family and domain databases

    Gene3Di3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPiMF_00145. Phosphoglyc_kinase.
    InterProiIPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view]
    PANTHERiPTHR11406. PTHR11406. 1 hit.
    PfamiPF00162. PGK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000724. Pgk. 1 hit.
    PRINTSiPR00477. PHGLYCKINASE.
    SUPFAMiSSF53748. SSF53748. 1 hit.
    PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9Z519-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKTIDELLSE GVAGKRVFVR ADLNVPLDGT TITDDGRIRA VVPTVKALAD    50
    AGARVIVASH LGRPKGAPDP AFSLAPAAAR LGELLGADVA FAEDTVGSSA 100
    EAVVTGLADG GVAVIENLRF NAGETSKDDA ERAAFADKLA GLADVYVGDG 150
    FGAVHRKHAS VFDLPKRLPH YAGYLIATEV GVLKKLTDEV KRPYVVALGG 200
    AKVSDKLAVI DQLLGKADRL LIGGGMAYTF LKAKGYEVGI SLLQEDQIPA 250
    VKEYIERAEK NGVELVLPVD VLVAPEFPDL KTKAPANPTT VAADAIPADQ 300
    EGLDIGPETR KLYASKLADA GTVFWNGPMG VFEHPDYAEG TKAVAQALVD 350
    APGFTVVGGG DSAAAVRTLG FDENAFGHIS TGGGASLEYL EGKTLPGLAA 400
    LED 403
    Length:403
    Mass (Da):41,765
    Last modified:May 1, 1999 - v1
    Checksum:iC42094E7C6221FE5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL939110 Genomic DNA. Translation: CAB38136.1.
    PIRiT36019.
    RefSeqiNP_626210.1. NC_003888.3.

    Genome annotation databases

    EnsemblBacteriaiCAB38136; CAB38136; CAB38136.
    GeneIDi1097380.
    KEGGisco:SCO1946.
    PATRICi23733526. VBIStrCoe124346_1973.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL939110 Genomic DNA. Translation: CAB38136.1 .
    PIRi T36019.
    RefSeqi NP_626210.1. NC_003888.3.

    3D structure databases

    ProteinModelPortali Q9Z519.
    SMRi Q9Z519. Positions 1-403.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 100226.SCO1946.

    Proteomic databases

    PRIDEi Q9Z519.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAB38136 ; CAB38136 ; CAB38136 .
    GeneIDi 1097380.
    KEGGi sco:SCO1946.
    PATRICi 23733526. VBIStrCoe124346_1973.

    Phylogenomic databases

    eggNOGi COG0126.
    HOGENOMi HOG000227107.
    KOi K00927.
    OMAi AGHPVGK.
    OrthoDBi EOG64N9Z0.
    PhylomeDBi Q9Z519.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00185 .

    Family and domain databases

    Gene3Di 3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPi MF_00145. Phosphoglyc_kinase.
    InterProi IPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view ]
    PANTHERi PTHR11406. PTHR11406. 1 hit.
    Pfami PF00162. PGK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000724. Pgk. 1 hit.
    PRINTSi PR00477. PHGLYCKINASE.
    SUPFAMi SSF53748. SSF53748. 1 hit.
    PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-471 / A3(2) / M145.

    Entry informationi

    Entry nameiPGK_STRCO
    AccessioniPrimary (citable) accession number: Q9Z519
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2000
    Last sequence update: May 1, 1999
    Last modified: October 1, 2014
    This is version 91 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3