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Protein

6-phosphogluconolactonase

Gene

pgl

Organism
Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

Catalytic activityi

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.

Pathwayi

GO - Molecular functioni

  1. 6-phosphogluconolactonase activity Source: UniProtKB-EC

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
  2. pentose-phosphate shunt Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciSMEL266834:GJF6-720-MONOMER.
UniPathwayiUPA00115; UER00409.

Names & Taxonomyi

Protein namesi
Recommended name:
6-phosphogluconolactonase (EC:3.1.1.31)
Short name:
6PGL
Gene namesi
Name:pgl
Synonyms:devB
Ordered Locus Names:R00703
ORF Names:SMc03069
OrganismiRhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Taxonomic identifieri266834 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
ProteomesiUP000001976 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 2322326-phosphogluconolactonasePRO_0000090105Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi266834.SMc03069.

Structurei

3D structure databases

ProteinModelPortaliQ9Z3S1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0363.
HOGENOMiHOG000256284.
KOiK01057.
OMAiNDERWVP.
OrthoDBiEOG63FW46.

Family and domain databases

InterProiIPR005900. 6-phosphogluconolactonase_DevB.
IPR006148. Glc/Gal-6P_isomerase.
[Graphical view]
PfamiPF01182. Glucosamine_iso. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01198. pgl. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9Z3S1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSANMHIFEN PSALAEALAD DVGARLAAAI AARGTASLAV SGGSTPKAFF
60 70 80 90 100
RSLSRRELDW SKVTVTLVDE RFVPPENDRS NHRLVADNLL KDGAAEARFV
110 120 130 140 150
PLYQAAETAE AAAAIASGRT ASLGAPLDVV VLGMGTDGHT ASFFPGGTRL
160 170 180 190 200
EEALDPTTPR GVITMEAEGA GEPRLTFTFS SLQDAGYLVL HIEGSGKKEV
210 220 230
LAQAEASGDE AEMPIRAMLR RAASPLQIYW AP
Length:232
Mass (Da):24,408
Last modified:October 24, 2001 - v2
Checksum:i5A29D02A62FCEED7
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti184 – 22744Missing in AAD12044 (PubMed:10400573).CuratedAdd
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF045609 Genomic DNA. Translation: AAD12044.1.
AL591688 Genomic DNA. Translation: CAC45275.1.
RefSeqiNP_384809.1. NC_003047.1.

Genome annotation databases

EnsemblBacteriaiCAC45275; CAC45275; SMc03069.
GeneIDi1232342.
KEGGisme:SMc03069.
PATRICi23630627. VBISinMel96828_2079.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF045609 Genomic DNA. Translation: AAD12044.1.
AL591688 Genomic DNA. Translation: CAC45275.1.
RefSeqiNP_384809.1. NC_003047.1.

3D structure databases

ProteinModelPortaliQ9Z3S1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi266834.SMc03069.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAC45275; CAC45275; SMc03069.
GeneIDi1232342.
KEGGisme:SMc03069.
PATRICi23630627. VBISinMel96828_2079.

Phylogenomic databases

eggNOGiCOG0363.
HOGENOMiHOG000256284.
KOiK01057.
OMAiNDERWVP.
OrthoDBiEOG63FW46.

Enzyme and pathway databases

UniPathwayiUPA00115; UER00409.
BioCyciSMEL266834:GJF6-720-MONOMER.

Family and domain databases

InterProiIPR005900. 6-phosphogluconolactonase_DevB.
IPR006148. Glc/Gal-6P_isomerase.
[Graphical view]
PfamiPF01182. Glucosamine_iso. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01198. pgl. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "A novel Sinorhizobium meliloti operon encodes an alpha-glucosidase and a periplasmic-binding-protein-dependent transport system for alpha-glucosides."
    Willis L.B., Walker G.C.
    J. Bacteriol. 181:4176-4184(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1021.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1021.

Entry informationi

Entry namei6PGL_RHIME
AccessioniPrimary (citable) accession number: Q9Z3S1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: October 24, 2001
Last modified: March 4, 2015
This is version 81 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

Seems to have a sequencing error in the C-terminal region when compared to orthologs, but the potentially correct sequence could not be inferred.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.