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Q9Z3R8

- AGLA_RHIME

UniProt

Q9Z3R8 - AGLA_RHIME

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Protein
Probable alpha-glucosidase
Gene
aglA, R00698, SMc03064
Organism
Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei212 – 2121Nucleophile By similarity
Active sitei272 – 2721Proton donor By similarity
Sitei345 – 3451Transition state stabilizer By similarity

GO - Molecular functioni

  1. cation binding Source: InterPro
  2. maltose alpha-glucosidase activity Source: UniProtKB-EC

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Enzyme and pathway databases

BioCyciSMEL266834:GJF6-715-MONOMER.

Protein family/group databases

CAZyiGH13. Glycoside Hydrolase Family 13.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable alpha-glucosidase (EC:3.2.1.20)
Gene namesi
Name:aglA
Ordered Locus Names:R00698
ORF Names:SMc03064
OrganismiRhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Taxonomic identifieri266834 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
ProteomesiUP000001976: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 551551Probable alpha-glucosidase
PRO_0000054312Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi266834.SMc03064.

Structurei

3D structure databases

ProteinModelPortaliQ9Z3R8.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0366.
HOGENOMiHOG000220640.
KOiK01187.
OMAiTREYGNE.
OrthoDBiEOG6RVFV2.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 2 hits.
InterProiIPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR006589. Glyco_hydro_13_sub_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
[Graphical view]
SMARTiSM00642. Aamy. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9Z3R8-1 [UniParc]FASTAAdd to Basket

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MTMNETTSSL LEPDRDWWRG AVIYQIYPRS FQDTNGDGIG DLQGITARLP    50
HIAGLGADAI WISPFFTSPM RDFGYDVSNY VDVDPIFGTL EDFDALIAEA 100
HRLGLRVMID LVLSHTSDRH PWFVESRSSR SNAKADWYVW ADSKPDGTPP 150
NNWLSIFGGS AWQWDPTRLQ YYLHNFLTSQ PDLNLHNPQV QEALLAVERF 200
WLERGVDGFR LDTINFYFHD RELRDNPALV PERRNASTAP AVNPYNYQEH 250
IYDKNRPENL EFLKRFRAVM DEFPAIAAVG EVGDSQRGLE IAGEYTSGGD 300
KVHMCYAFEF LAPDRLTPQR VAEVLRDFHR AAPEGWACWA FSNHDVVRHV 350
SRWADGVTDH DAHAKLLASL LMSLRGTVCI YQGEELALAE AELDYEDLQD 400
PYGIQFWPDF KGRDGCRTPM VWESLPDGGF SSATPWLPIS QSHIPRAVAV 450
QEGDPASVLH HYRRFLAFRK ANPALAKGEI EFVETRGSLL GFLRSHGNEK 500
VFCLFNMSDE AATKELPMKR LEPLEGHGFV SEILDHEVKL PAWGAFFARL 550
A 551
Length:551
Mass (Da):62,576
Last modified:November 2, 2001 - v2
Checksum:iBB7BD3E17C935509
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti13 – 131P → A in AAD12047. 1 Publication
Sequence conflicti20 – 212GA → RP in AAD12047. 1 Publication
Sequence conflicti402 – 41514YGIQF…KGRDG → MASSSGPTSSAGR1 Publication
Add
BLAST
Sequence conflicti445 – 46016PRAVA…ASVLH → RGRCRAGGRPGLGAA in AAD12047. 1 Publication
Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF045609 Genomic DNA. Translation: AAD12047.1.
AL591688 Genomic DNA. Translation: CAC45270.1.
RefSeqiNP_384804.1. NC_003047.1.

Genome annotation databases

EnsemblBacteriaiCAC45270; CAC45270; SMc03064.
GeneIDi1232337.
KEGGisme:SMc03064.
PATRICi23630615. VBISinMel96828_2073.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF045609 Genomic DNA. Translation: AAD12047.1 .
AL591688 Genomic DNA. Translation: CAC45270.1 .
RefSeqi NP_384804.1. NC_003047.1.

3D structure databases

ProteinModelPortali Q9Z3R8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 266834.SMc03064.

Protein family/group databases

CAZyi GH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAC45270 ; CAC45270 ; SMc03064 .
GeneIDi 1232337.
KEGGi sme:SMc03064.
PATRICi 23630615. VBISinMel96828_2073.

Phylogenomic databases

eggNOGi COG0366.
HOGENOMi HOG000220640.
KOi K01187.
OMAi TREYGNE.
OrthoDBi EOG6RVFV2.

Enzyme and pathway databases

BioCyci SMEL266834:GJF6-715-MONOMER.

Family and domain databases

Gene3Di 2.60.40.1180. 1 hit.
3.20.20.80. 2 hits.
InterProi IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR006589. Glyco_hydro_13_sub_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view ]
PANTHERi PTHR10357. PTHR10357. 1 hit.
Pfami PF00128. Alpha-amylase. 1 hit.
[Graphical view ]
SMARTi SM00642. Aamy. 1 hit.
[Graphical view ]
SUPFAMi SSF51445. SSF51445. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A novel Sinorhizobium meliloti operon encodes an alpha-glucosidase and a periplasmic-binding-protein-dependent transport system for alpha-glucosides."
    Willis L.B., Walker G.C.
    J. Bacteriol. 181:4176-4184(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1021.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1021.

Entry informationi

Entry nameiAGLA_RHIME
AccessioniPrimary (citable) accession number: Q9Z3R8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 2, 2001
Last modified: May 14, 2014
This is version 88 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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