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Protein
Submitted name:

Replication factor C

Gene

Rfc1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • ATP binding Source: InterPro
  • DNA clamp loader activity Source: InterPro
  • double-stranded DNA binding Source: RGD
  • sequence-specific DNA binding Source: RGD

GO - Biological processi

  • DNA repair Source: InterPro
  • DNA replication Source: InterPro
  • negative regulation of transcription, DNA-templated Source: RGD
  • negative regulation of transcription by RNA polymerase II Source: RGD
  • positive regulation of transcription, DNA-templated Source: RGD

Names & Taxonomyi

Protein namesi
Submitted name:
Replication factor CImported
Gene namesi
Name:Rfc1Imported
Synonyms:Recc1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi620619 Rfc1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiQ9Z2R7

PTM databases

iPTMnetiQ9Z2R7

Expressioni

Gene expression databases

GenevisibleiQ9Z2R7 RN

Structurei

3D structure databases

ProteinModelPortaliQ9Z2R7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini399 – 477BRCTInterPro annotationAdd BLAST79

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili319 – 339Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOVERGENiHBG004167
KOiK10754
PhylomeDBiQ9Z2R7

Family and domain databases

CDDicd00027 BRCT, 1 hit
Gene3Di3.40.50.10190, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003959 ATPase_AAA_core
IPR001357 BRCT_dom
IPR036420 BRCT_dom_sf
IPR008921 DNA_pol3_clamp-load_cplx_C
IPR013725 DNA_replication_fac_RFC1_C
IPR027417 P-loop_NTPase
IPR012178 RFC1
PfamiView protein in Pfam
PF00004 AAA, 1 hit
PF00533 BRCT, 1 hit
PF08519 RFC1, 1 hit
PIRSFiPIRSF036578 RFC1, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SM00292 BRCT, 1 hit
SUPFAMiSSF48019 SSF48019, 1 hit
SSF52113 SSF52113, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50172 BRCT, 1 hit

Sequencei

Sequence statusi: Fragment.

Q9Z2R7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDIRKFFGVI SSGKKPVNET VKKNEKTKPS EGTVKGKKGV KVAKVNNPCK
60 70 80 90 100
EDASRPKQHT EKRGSSMTQI QNQRRHVQVK DAKKKSEKLP RVLVNLVNLS
110 120 130 140 150
EGSSLPHISE TDEDAVTFYV KRQPPNQKRM EYLRNSYLGA SNVKKNEENT
160 170 180 190 200
KTKSKPLSPI KLTPTSVLDY FGTESVQRSG KKMVASKKKE SSQTPDDSRL
210 220 230 240 250
NDEAIAKQLQ LDEDAELERQ LHEDEEFART LALLDEEPKT KKARKDSEEG
260 270 280 290 300
ESFSPAKAEL SKAAKQKSPA NEHFSIGRKT YSPAKYGKGR GSEGTKQPCR
310 320 330 340 350
SAHQTEACSS LKASSKLALM KAQEENSHTD TELLAAKRES AIEPKGEKTT
360 370 380 390 400
PRKTKGSPTK RESVSPEDSE KKRTNYQAYR SYLNREGPKA LGSKEIPKGA
410 420 430 440 450
ENCLEGLTFV ITGVLESIER EEAKSLIERY GGKVTGNVSK KTSYLVMGRD
460 470 480 490 500
SRQSKSDKAA ALGTKILDED GLLDLIRTMP GKKSKYEIAA EAEMKKEKSK
510 520 530 540 550
LERTPQKNDQ GKRKLSPTKR ELEPKKSKLT PLKHSPRKAV KEEERVCPRG
560 570 580 590 600
LDAKEPHGSH SASREECLLW VDKYKPTSLK NIIGQQGDQS CANKLLRWLR
610 620 630 640 650
NWHKSSPEEK KHAKFGKVAS KDDGSSFKAA LLSGPPGVGK TTTASLVCQE
660 670 680 690 700
LGYSYVELNA SDTRSKNSLK AIVAESLNNT SIKGFYTSGA SPSVSARHAL
710 720 730 740 750
IMDEVDGMAG NEDRGGIQEL IGLIKHTKIP IICMCNDRNH PKIRSLVHYC
760 770 780 790 800
FDLRFQRPRV EQIKSAMLSI AFKEGLKIPP PAMNEIILGA NQDVRQVLHN
810 820 830 840 850
LSMWCAQSKV LTYDQAKADS QRAKKDIRLG PFDVTRKVFA AGEETPHMSL
860 870 880 890 900
MDKSDLFFHD YSIAPLFVQE NYLHVKPVAA GGDMKKHLML LSRAADSICD
910 920 930 940 950
GDLVANQIRS KQNWSLSHTG HLRQRCSWRV DEGLHVSVSQ LPKAGWESTR
960 970 980 990 1000
LWASTDRTVQ DLSLHMSLRT YSSKRTVNMD YLSHIRDALV RPLTSQGVEG
1010 1020 1030 1040 1050
VQRVVTLMLV KEDFDNIMEV SSDTYYWGGK PSTFSKLDPK VKAAFTRAYN
1060 1070 1080 1090 1100
KEAHLTPYSL QVVKASRPSI GPALDSEYNE ESQEDATQSD EKEQDALETD

AMIK
Length:1,104
Mass (Da):123,247
Last modified:May 1, 1999 - v1
Checksum:iB8E1E4BCE650793B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1104Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF030050 mRNA Translation: AAD01890.1
RefSeqiNP_445999.1, NM_053547.1
UniGeneiRn.103272

Genome annotation databases

GeneIDi89809
KEGGirno:89809
UCSCiRGD:620619 rat

Similar proteinsi

Entry informationi

Entry nameiQ9Z2R7_RAT
AccessioniPrimary (citable) accession number: Q9Z2R7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: May 23, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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