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Protein

Zinc finger protein 394

Gene

Znf394

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri328 – 350C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri356 – 378C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri384 – 406C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri412 – 433C2H2-type 4; atypicalPROSITE-ProRule annotationAdd BLAST22
Zinc fingeri439 – 461C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri467 – 489C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri495 – 517C2H2-type 7PROSITE-ProRule annotationAdd BLAST23

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 394
Alternative name(s):
RLZF-Y
Zinc finger protein 94
Short name:
Zfp-94
Zinc finger protein Y1
Gene namesi
Name:Znf394
Synonyms:Rlzfy, Zfp394, Zfp94, Zfp99
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi628654 Zfp394

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000475601 – 536Zinc finger protein 394Add BLAST536

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki20Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki207Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki260Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki413Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

PaxDbiQ9Z2K3
PRIDEiQ9Z2K3

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000001302

Structurei

3D structure databases

ProteinModelPortaliQ9Z2K3
SMRiQ9Z2K3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini44 – 126SCAN boxPROSITE-ProRule annotationAdd BLAST83
Domaini135 – 196KRABAdd BLAST62

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri328 – 350C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri356 – 378C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri384 – 406C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri412 – 433C2H2-type 4; atypicalPROSITE-ProRule annotationAdd BLAST22
Zinc fingeri439 – 461C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri467 – 489C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri495 – 517C2H2-type 7PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
HOGENOMiHOG000234619
HOVERGENiHBG018163
InParanoidiQ9Z2K3
KOiK09229
PhylomeDBiQ9Z2K3

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
cd07936 SCAN, 1 hit
Gene3Di1.10.4020.10, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR003309 SCAN_dom
IPR038269 SCAN_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF02023 SCAN, 1 hit
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00431 SCAN, 1 hit
SM00355 ZnF_C2H2, 7 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 4 hits
PROSITEiView protein in PROSITE
PS50804 SCAN_BOX, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 6 hits
PS50157 ZINC_FINGER_C2H2_2, 7 hits

Sequencei

Sequence statusi: Complete.

Q9Z2K3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAGSGVAPP PLGVGLCAVK VEEDSPGSQE PSGSGDWQNP ETSRKQFRQL
60 70 80 90 100
RYQEVAGPEE ALSRLWELCR RWLRPELRSK EQIMELLVLE QFLTILPREL
110 120 130 140 150
QAYVRDHCPE SGEEAAALAR TLQRALDGAS LQSFATFKDV AESLTWEEWE
160 170 180 190 200
QLAAARKGFC RESTKDPGST VGPGLETKAV TTDVILKQEM SKEAESQAWL
210 220 230 240 250
QEVSQGKVPV FTKCGDTWED WEERLPKAAE LLPLQSSPEE QGRTAIPHLL
260 270 280 290 300
GVSKDESDSK DNEFENSGSL VLGQHIQTAE GLVTNGECGE DHKQGLHAKC
310 320 330 340 350
HTVKPHSSVD NALGLLESQR HFQEGRPYKC DNCEKRFRQR SDLFKHQRTH
360 370 380 390 400
TGEKPYQCQE CGKSFSQSAA LVKHQRTHTG EKPYACPECG ECFRQSSHLS
410 420 430 440 450
RHQRTHGSEK YCKCEECGEI FHISSLFKHQ RLHKGERPHK CEVCEKSFKQ
460 470 480 490 500
RSDLFKHQRI HTGEKPYMCF VCERRFSQSA TLIKHQRTHT GEKPYKCFQC
510 520 530
GERFRQSTHL VRHQRIHHNS VSGLRVEKQH GNLLSW
Length:536
Mass (Da):60,987
Last modified:May 1, 1999 - v1
Checksum:i9359894B2565ACD4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF052042 mRNA Translation: AAC78780.1
RefSeqiNP_663776.1, NM_145724.1
UniGeneiRn.101891

Genome annotation databases

GeneIDi252860
KEGGirno:252860

Similar proteinsi

Entry informationi

Entry nameiZN394_RAT
AccessioniPrimary (citable) accession number: Q9Z2K3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 1999
Last modified: March 28, 2018
This is version 130 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health