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Protein

Zinc finger protein 394

Gene

Znf394

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri328 – 35023C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri356 – 37823C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri384 – 40623C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri412 – 43322C2H2-type 4; atypicalPROSITE-ProRule annotationAdd
BLAST
Zinc fingeri439 – 46123C2H2-type 5PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri467 – 48923C2H2-type 6PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri495 – 51723C2H2-type 7PROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 394
Alternative name(s):
RLZF-Y
Zinc finger protein 94
Short name:
Zfp-94
Zinc finger protein Y1
Gene namesi
Name:Znf394
Synonyms:Rlzfy, Zfp394, Zfp94, Zfp99
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi628654. Zfp394.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 536536Zinc finger protein 394PRO_0000047560Add
BLAST

Proteomic databases

PaxDbiQ9Z2K3.
PRIDEiQ9Z2K3.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000001302.

Structurei

3D structure databases

ProteinModelPortaliQ9Z2K3.
SMRiQ9Z2K3. Positions 35-128, 321-518.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini44 – 12683SCAN boxPROSITE-ProRule annotationAdd
BLAST
Domaini135 – 19662KRABAdd
BLAST

Sequence similaritiesi

Contains 7 C2H2-type zinc fingers.PROSITE-ProRule annotation
Contains 1 KRAB domain.Curated
Contains 1 SCAN box domain.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri328 – 35023C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri356 – 37823C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri384 – 40623C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri412 – 43322C2H2-type 4; atypicalPROSITE-ProRule annotationAdd
BLAST
Zinc fingeri439 – 46123C2H2-type 5PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri467 – 48923C2H2-type 6PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri495 – 51723C2H2-type 7PROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
HOGENOMiHOG000234619.
HOVERGENiHBG018163.
InParanoidiQ9Z2K3.
KOiK09229.
PhylomeDBiQ9Z2K3.

Family and domain databases

CDDicd07765. KRAB_A-box. 1 hit.
Gene3Di3.30.160.60. 7 hits.
InterProiIPR001909. KRAB.
IPR008916. Retrov_capsid_C.
IPR003309. SCAN_dom.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF01352. KRAB. 1 hit.
PF02023. SCAN. 1 hit.
PF00096. zf-C2H2. 4 hits.
[Graphical view]
SMARTiSM00349. KRAB. 1 hit.
SM00431. SCAN. 1 hit.
SM00355. ZnF_C2H2. 7 hits.
[Graphical view]
SUPFAMiSSF109640. SSF109640. 1 hit.
SSF47353. SSF47353. 1 hit.
PROSITEiPS50804. SCAN_BOX. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 6 hits.
PS50157. ZINC_FINGER_C2H2_2. 7 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9Z2K3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAGSGVAPP PLGVGLCAVK VEEDSPGSQE PSGSGDWQNP ETSRKQFRQL
60 70 80 90 100
RYQEVAGPEE ALSRLWELCR RWLRPELRSK EQIMELLVLE QFLTILPREL
110 120 130 140 150
QAYVRDHCPE SGEEAAALAR TLQRALDGAS LQSFATFKDV AESLTWEEWE
160 170 180 190 200
QLAAARKGFC RESTKDPGST VGPGLETKAV TTDVILKQEM SKEAESQAWL
210 220 230 240 250
QEVSQGKVPV FTKCGDTWED WEERLPKAAE LLPLQSSPEE QGRTAIPHLL
260 270 280 290 300
GVSKDESDSK DNEFENSGSL VLGQHIQTAE GLVTNGECGE DHKQGLHAKC
310 320 330 340 350
HTVKPHSSVD NALGLLESQR HFQEGRPYKC DNCEKRFRQR SDLFKHQRTH
360 370 380 390 400
TGEKPYQCQE CGKSFSQSAA LVKHQRTHTG EKPYACPECG ECFRQSSHLS
410 420 430 440 450
RHQRTHGSEK YCKCEECGEI FHISSLFKHQ RLHKGERPHK CEVCEKSFKQ
460 470 480 490 500
RSDLFKHQRI HTGEKPYMCF VCERRFSQSA TLIKHQRTHT GEKPYKCFQC
510 520 530
GERFRQSTHL VRHQRIHHNS VSGLRVEKQH GNLLSW
Length:536
Mass (Da):60,987
Last modified:May 1, 1999 - v1
Checksum:i9359894B2565ACD4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF052042 mRNA. Translation: AAC78780.1.
RefSeqiNP_663776.1. NM_145724.1.
UniGeneiRn.101891.

Genome annotation databases

GeneIDi252860.
KEGGirno:252860.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF052042 mRNA. Translation: AAC78780.1.
RefSeqiNP_663776.1. NM_145724.1.
UniGeneiRn.101891.

3D structure databases

ProteinModelPortaliQ9Z2K3.
SMRiQ9Z2K3. Positions 35-128, 321-518.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000001302.

Proteomic databases

PaxDbiQ9Z2K3.
PRIDEiQ9Z2K3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi252860.
KEGGirno:252860.

Organism-specific databases

CTDi252860.
RGDi628654. Zfp394.

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
HOGENOMiHOG000234619.
HOVERGENiHBG018163.
InParanoidiQ9Z2K3.
KOiK09229.
PhylomeDBiQ9Z2K3.

Miscellaneous databases

PROiQ9Z2K3.

Family and domain databases

CDDicd07765. KRAB_A-box. 1 hit.
Gene3Di3.30.160.60. 7 hits.
InterProiIPR001909. KRAB.
IPR008916. Retrov_capsid_C.
IPR003309. SCAN_dom.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF01352. KRAB. 1 hit.
PF02023. SCAN. 1 hit.
PF00096. zf-C2H2. 4 hits.
[Graphical view]
SMARTiSM00349. KRAB. 1 hit.
SM00431. SCAN. 1 hit.
SM00355. ZnF_C2H2. 7 hits.
[Graphical view]
SUPFAMiSSF109640. SSF109640. 1 hit.
SSF47353. SSF47353. 1 hit.
PROSITEiPS50804. SCAN_BOX. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 6 hits.
PS50157. ZINC_FINGER_C2H2_2. 7 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiZN394_RAT
AccessioniPrimary (citable) accession number: Q9Z2K3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 1999
Last modified: September 7, 2016
This is version 119 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.