##gff-version 3
Q9Z2D6	UniProtKB	Chain	1	484	.	.	.	ID=PRO_0000096347;Note=Methyl-CpG-binding protein 2	
Q9Z2D6	UniProtKB	Domain	90	162	.	.	.	Note=MBD;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00338	
Q9Z2D6	UniProtKB	DNA binding	185	197	.	.	.	Note=A.T hook 1	
Q9Z2D6	UniProtKB	DNA binding	265	277	.	.	.	Note=A.T hook 2	
Q9Z2D6	UniProtKB	Region	1	119	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9Z2D6	UniProtKB	Region	147	216	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9Z2D6	UniProtKB	Region	249	278	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9Z2D6	UniProtKB	Region	269	309	.	.	.	Note=Interaction with NCOR2;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:23770565;Dbxref=PMID:23770565	
Q9Z2D6	UniProtKB	Region	285	309	.	.	.	Note=Interaction with TBL1XR1;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:28348241;Dbxref=PMID:28348241	
Q9Z2D6	UniProtKB	Region	319	484	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9Z2D6	UniProtKB	Compositional bias	8	49	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9Z2D6	UniProtKB	Compositional bias	83	109	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9Z2D6	UniProtKB	Compositional bias	251	267	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9Z2D6	UniProtKB	Compositional bias	380	398	.	.	.	Note=Pro residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9Z2D6	UniProtKB	Compositional bias	446	484	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9Z2D6	UniProtKB	Modified residue	13	13	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q00566	
Q9Z2D6	UniProtKB	Modified residue	80	80	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079	
Q9Z2D6	UniProtKB	Modified residue	116	116	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P51608	
Q9Z2D6	UniProtKB	Modified residue	162	162	.	.	.	Note=Omega-N-methylarginine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:24129315;Dbxref=PMID:24129315	
Q9Z2D6	UniProtKB	Modified residue	216	216	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P51608	
Q9Z2D6	UniProtKB	Modified residue	229	229	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079	
Q9Z2D6	UniProtKB	Modified residue	321	321	.	.	.	Note=N6-acetyllysine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:23806337;Dbxref=PMID:23806337	
Q9Z2D6	UniProtKB	Modified residue	421	421	.	.	.	Note=Phosphoserine%3B by CaMK2;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17046689;Dbxref=PMID:17046689	
Q9Z2D6	UniProtKB	Modified residue	424	424	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079	
Q9Z2D6	UniProtKB	Modified residue	447	447	.	.	.	Note=N6-acetyllysine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:23806337;Dbxref=PMID:23806337	
Q9Z2D6	UniProtKB	Alternative sequence	1	9	.	.	.	ID=VSP_022949;Note=In isoform B. MVAGMLGLR->MAAAAATAAAAAAPSGGGGGGEEERL;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:16141072;Dbxref=PMID:16141072	
Q9Z2D6	UniProtKB	Mutagenesis	158	158	.	.	.	Note=Loss of localization to the nucleus. Distributes diffusely in cells. Interacts normally with NCOR2. T->M;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:23770565;Dbxref=PMID:23770565	
Q9Z2D6	UniProtKB	Mutagenesis	302	302	.	.	.	Note=Abolishes interaction with NCOR2. P->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:23770565;Dbxref=PMID:23770565	
Q9Z2D6	UniProtKB	Mutagenesis	304	304	.	.	.	Note=Abolishes interaction with NCOR2. K->E;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:23770565;Dbxref=PMID:23770565	
Q9Z2D6	UniProtKB	Mutagenesis	305	305	.	.	.	Note=Abolishes interaction with NCOR2. K->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:23770565;Dbxref=PMID:23770565	
Q9Z2D6	UniProtKB	Mutagenesis	306	306	.	.	.	Note=Abolishes interaction with NCOR2. Mice exhibit a severe neurological Rett syndrome-like phenotype. R->C;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:23770565;Dbxref=PMID:23770565	
Q9Z2D6	UniProtKB	Sequence conflict	328	328	.	.	.	Note=L->P;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q9Z2D6	UniProtKB	Helix	298	300	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5NAF	
Q9Z2D6	UniProtKB	Helix	303	305	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5NAF