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Protein
Submitted name:

Patched

Gene

Ptch1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
PatchedImported
Gene namesi
Name:Ptch1Imported
Synonyms:ptcImported, PtchImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi621425. Ptch1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei425 – 444HelicalSequence analysisAdd BLAST20
Transmembranei456 – 481HelicalSequence analysisAdd BLAST26
Transmembranei487 – 509HelicalSequence analysisAdd BLAST23
Transmembranei530 – 553HelicalSequence analysisAdd BLAST24
Transmembranei559 – 582HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ9Z2A1.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ9Z2A1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini424 – 584SSDInterPro annotationAdd BLAST161

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1935. Eukaryota.
ENOG410XRKU. LUCA.
HOVERGENiHBG003801.
PhylomeDBiQ9Z2A1.

Family and domain databases

InterProiView protein in InterPro
IPR000731. SSD.
IPR004766. TM_rcpt_patched.
PfamiView protein in Pfam
PF12349. Sterol-sensing. 1 hit.
TIGRFAMsiTIGR00918. 2A060602. 1 hit.
PROSITEiView protein in PROSITE
PS50156. SSD. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q9Z2A1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASAGNAAGA LGRQAGGGRR RRTGGPHRAA PDRDYLHRPS YCDAAFAMEQ
60 70 80 90 100
ISKGKATGRK APLWLRAKFQ RLLFKLGCYI QKDCGKFLVV GLLIFGAFAV
110 120 130 140 150
GLKAANLETN VEELWVEVGG RVSRELNYTR QKIGEEAMFN PQLMIQTPKE
160 170 180 190 200
EGANVLTTEA LLQHLDSALQ ASRVHVYMYN RQWKLEHLCY KSGELITETG
210 220 230 240 250
YMDQIIEYLY PCLIITPLDC FWEGAKLQSG TAYLLGKPPL RWTNFDPLEF
260 270 280 290 300
LEELKKINYQ VDSWEEMLNK AEVGHGYMDR PCLNPADPDC PATAPNKNST
310 320 330 340 350
KPLDVALVLN GGCQGLSRKY MHWQEELIVG GTVKNATGKL VSAHALQTMF
360 370 380 390 400
QLMTPKQMYE HFRGYDYVSH INWNEDRAAA ILEAWQRTYV EVVHQSVAPN
410 420 430 440 450
STQKVLSFTT RTLDDILKSF SDVSVIRVAS GYLLMLAYAC LTMLRWDCSK
460 470 480 490 500
SQGAVGLAGV LLVALSVAAG LGLCSLIGIS FNAATTQVLP FLALGVGVDD
510 520 530 540 550
VFLLAHAFSE TGQNKRIPIE DRTGECLKRT GASVALTSIS NVTAFFMAAL
560 570 580 590 600
IPIPALRAFS LQAAVVVVFN FAMVLLIFPA ILSMDLYRRE DRRLDIFCCF

TSPCVSLV
Length:608
Mass (Da):67,328
Last modified:May 1, 1999 - v1
Checksum:i73F505A1512EE9C5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei608Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF079162 mRNA. Translation: AAC99398.1.
UniGeneiRn.102312.

Genome annotation databases

UCSCiRGD:621425. rat.

Similar proteinsi

Entry informationi

Entry nameiQ9Z2A1_RAT
AccessioniPrimary (citable) accession number: Q9Z2A1
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: November 22, 2017
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)