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Protein

Chorion-specific transcription factor GCMa

Gene

Gcm1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Transcription factor that is necessary for placental development.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi76 – 761Zinc 1PROSITE-ProRule annotation
Metal bindingi82 – 821Zinc 2PROSITE-ProRule annotation
Metal bindingi86 – 861Zinc 2PROSITE-ProRule annotation
Metal bindingi113 – 1131Zinc 2PROSITE-ProRule annotation
Metal bindingi116 – 1161Zinc 2PROSITE-ProRule annotation
Metal bindingi125 – 1251Zinc 1PROSITE-ProRule annotation
Metal bindingi152 – 1521Zinc 1PROSITE-ProRule annotation
Metal bindingi154 – 1541Zinc 1PROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi14 – 169156GCMPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Developmental protein

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Chorion-specific transcription factor GCMa
Alternative name(s):
GCM motif protein 1
Glial cells missing homolog 1
Gene namesi
Name:Gcm1
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 8

Organism-specific databases

RGDi61852. Gcm1.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 436436Chorion-specific transcription factor GCMaPRO_0000126649Add
BLAST

Post-translational modificationi

Polyubiquitinated in the presence of UBE2D2 and FBXW2 (in vitro).By similarity

Keywords - PTMi

Ubl conjugation

Proteomic databases

PaxDbiQ9Z288.
PRIDEiQ9Z288.

PTM databases

iPTMnetiQ9Z288.
PhosphoSiteiQ9Z288.

Expressioni

Gene expression databases

BgeeiENSRNOG00000007932.
GenevisibleiQ9Z288. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000010583.

Structurei

3D structure databases

ProteinModelPortaliQ9Z288.
SMRiQ9Z288. Positions 14-170.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 GCM DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IKM6. Eukaryota.
ENOG4110IIJ. LUCA.
GeneTreeiENSGT00390000006777.
HOGENOMiHOG000112700.
HOVERGENiHBG039460.
InParanoidiQ9Z288.
OMAiWDFDEEM.
OrthoDBiEOG091G06SW.
PhylomeDBiQ9Z288.
TreeFamiTF324146.

Family and domain databases

InterProiIPR003902. Tscrpt_reg_GCM.
[Graphical view]
PfamiPF03615. GCM. 1 hit.
[Graphical view]
ProDomiPD014393. GCM_motif. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF90073. SSF90073. 1 hit.
PROSITEiPS50807. GCM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9Z288-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELDDFDPED KEILSWDIND MKLPQNVKKT DWFQEWPDSY VKHIYSSDDR
60 70 80 90 100
SAQRHLSSWA MRNTNNHNSR ILKKSCLGVV VCSRDCSTEE GRKIYLRPAI
110 120 130 140 150
CDKARQKQQR KSCPNCNGPL KLIPCRGHGG FPVTNFWRHD GRFIFFQSKG
160 170 180 190 200
EHDHPRPETK LEAEARRAMK KVHMASASSS LRMKGRPEMK GLPGEIPSQG
210 220 230 240 250
SLPLTWSFQE GVQLPSGYST PLIANAPQQN SLNDCLSFPK SYDLGGTTEL
260 270 280 290 300
EDPTSTLDPT KLYERYKFSS SKVYSAEDQF QPPVPGVYGD YDEAQTWNKN
310 320 330 340 350
AVLGRSPTDD TYYPPYPLPV ASWPCDYLPS QSSLEHSPQQ VPLEPPAAQP
360 370 380 390 400
GHHPLWTNPG GEPYEEKVPV DFSSYVPSVT YHSPQQDPFL LAYGSHPQQQ
410 420 430
YALPGKSNRW DFDEEMACMG LDHFNNEMLL NLCSLK
Length:436
Mass (Da):49,522
Last modified:May 1, 1999 - v1
Checksum:i042089C09BDCEC52
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF081557 mRNA. Translation: AAC64783.1.
RefSeqiNP_058882.1. NM_017186.2.
UniGeneiRn.30042.

Genome annotation databases

EnsembliENSRNOT00000010583; ENSRNOP00000010583; ENSRNOG00000007932.
GeneIDi29394.
KEGGirno:29394.
UCSCiRGD:61852. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF081557 mRNA. Translation: AAC64783.1.
RefSeqiNP_058882.1. NM_017186.2.
UniGeneiRn.30042.

3D structure databases

ProteinModelPortaliQ9Z288.
SMRiQ9Z288. Positions 14-170.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000010583.

PTM databases

iPTMnetiQ9Z288.
PhosphoSiteiQ9Z288.

Proteomic databases

PaxDbiQ9Z288.
PRIDEiQ9Z288.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000010583; ENSRNOP00000010583; ENSRNOG00000007932.
GeneIDi29394.
KEGGirno:29394.
UCSCiRGD:61852. rat.

Organism-specific databases

CTDi8521.
RGDi61852. Gcm1.

Phylogenomic databases

eggNOGiENOG410IKM6. Eukaryota.
ENOG4110IIJ. LUCA.
GeneTreeiENSGT00390000006777.
HOGENOMiHOG000112700.
HOVERGENiHBG039460.
InParanoidiQ9Z288.
OMAiWDFDEEM.
OrthoDBiEOG091G06SW.
PhylomeDBiQ9Z288.
TreeFamiTF324146.

Miscellaneous databases

PROiQ9Z288.

Gene expression databases

BgeeiENSRNOG00000007932.
GenevisibleiQ9Z288. RN.

Family and domain databases

InterProiIPR003902. Tscrpt_reg_GCM.
[Graphical view]
PfamiPF03615. GCM. 1 hit.
[Graphical view]
ProDomiPD014393. GCM_motif. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF90073. SSF90073. 1 hit.
PROSITEiPS50807. GCM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGCM1_RAT
AccessioniPrimary (citable) accession number: Q9Z288
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 25, 2003
Last sequence update: May 1, 1999
Last modified: September 7, 2016
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.