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Protein

Protein ABHD16A

Gene

Abhd16a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei355Charge relay systemBy similarity1
Active sitei430Charge relay systemBy similarity1
Active sitei507Charge relay systemBy similarity1

GO - Molecular functioni

  • acylglycerol lipase activity Source: BHF-UCL

GO - Biological processi

  • monoacylglycerol catabolic process Source: BHF-UCL
  • prostaglandin catabolic process Source: BHF-UCL
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Protein family/group databases

ESTHERimouse-Abhd16a. AlphaBeta_hydrolase.
MEROPSiS09.022.

Chemistry databases

SwissLipidsiSLP:000001040.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein ABHD16A (EC:3.-.-.-)
Alternative name(s):
Alpha/beta hydrolase domain-containing protein 16ACurated
Short name:
Abhydrolase domain-containing protein 16AImported
HLA-B-associated transcript 5
Gene namesi
Name:Abhd16aImported
Synonyms:Bat5, Ng26
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:99476. Abhd16a.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei60 – 80HelicalSequence analysisAdd BLAST21
Transmembranei93 – 113HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL5184.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000648341 – 558Protein ABHD16AAdd BLAST558

Proteomic databases

EPDiQ9Z1Q2.
MaxQBiQ9Z1Q2.
PaxDbiQ9Z1Q2.
PeptideAtlasiQ9Z1Q2.
PRIDEiQ9Z1Q2.

PTM databases

iPTMnetiQ9Z1Q2.
PhosphoSitePlusiQ9Z1Q2.
SwissPalmiQ9Z1Q2.

Expressioni

Gene expression databases

BgeeiENSMUSG00000007036.
CleanExiMM_BAT5.
ExpressionAtlasiQ9Z1Q2. baseline and differential.
GenevisibleiQ9Z1Q2. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000007251.

Structurei

3D structure databases

ProteinModelPortaliQ9Z1Q2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini281 – 406AB hydrolase-1Sequence analysisAdd BLAST126

Sequence similaritiesi

Belongs to the AB hydrolase superfamily. ABHD16 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1553. Eukaryota.
ENOG410XQU4. LUCA.
GeneTreeiENSGT00390000017119.
HOVERGENiHBG050666.
InParanoidiQ9Z1Q2.
OMAiPVDFDVK.
OrthoDBiEOG091G065R.
PhylomeDBiQ9Z1Q2.
TreeFamiTF314267.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR000073. AB_hydrolase_1.
IPR026604. ABHD16A.
[Graphical view]
PANTHERiPTHR12277:SF54. PTHR12277:SF54. 1 hit.
PfamiPF00561. Abhydrolase_1. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9Z1Q2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKLLSCVLG PRLYKIYRER DTDRAASSVP ETPTAVPAAS SSSWDTYYQP
60 70 80 90 100
RALEKHADSI LALASVFWSI SYYSSPFAFF YLYRKGYLSL SKVVPFSHYA
110 120 130 140 150
GTLLLLLAGV ACLRGIGRWT NPQYRQFITI LEATHRNQSA ENKRQLANYN
160 170 180 190 200
FDFRSWPVDF HWEEPSSRKG SRGGPSRRGV ALLRPEPLHR GTADTFLNRV
210 220 230 240 250
KKLPCQITSY LVAHTLGRRM LYPGSVYLLQ KALMPVLLQG QARLVEECNG
260 270 280 290 300
RRAKLLACDG NEIDTMFVDR RGTAEPQGQK LVICCEGNAG FYEVGCVSTP
310 320 330 340 350
LEAGYSVLGW NHPGFAGSTG VPFPQNEANA MDVVVQFAIH RLGFQPQDIV
360 370 380 390 400
IYAWSIGGFT ATWAAMSYPD ISAVILDASF DDLVPLALKV MPDSWRALVT
410 420 430 440 450
RTVRQHLNLN NSEQLCRFQG PVLLVRRTKD EIITTTVPED IMSNRGNDLL
460 470 480 490 500
LKLLQFRYPR VMVEEGLRAV RQWLEASSQL EEASIYSRWE VEEDWCVSVL
510 520 530 540 550
RSYQAEHGPD FPWSVGEDMS ADGRRQLALF LARKHLHNFE ATHCTPLPAQ

HFQMPWHL
Length:558
Mass (Da):63,086
Last modified:January 23, 2007 - v3
Checksum:i2DF1890F79E2EE63
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF109905 Genomic DNA. Translation: AAC84159.1.
BC029114 mRNA. Translation: AAH29114.1.
CCDSiCCDS28681.1.
RefSeqiNP_848707.1. NM_178592.3.
UniGeneiMm.43745.

Genome annotation databases

EnsembliENSMUST00000007251; ENSMUSP00000007251; ENSMUSG00000007036.
GeneIDi193742.
KEGGimmu:193742.
UCSCiuc008cfq.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF109905 Genomic DNA. Translation: AAC84159.1.
BC029114 mRNA. Translation: AAH29114.1.
CCDSiCCDS28681.1.
RefSeqiNP_848707.1. NM_178592.3.
UniGeneiMm.43745.

3D structure databases

ProteinModelPortaliQ9Z1Q2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000007251.

Chemistry databases

ChEMBLiCHEMBL5184.
SwissLipidsiSLP:000001040.

Protein family/group databases

ESTHERimouse-Abhd16a. AlphaBeta_hydrolase.
MEROPSiS09.022.

PTM databases

iPTMnetiQ9Z1Q2.
PhosphoSitePlusiQ9Z1Q2.
SwissPalmiQ9Z1Q2.

Proteomic databases

EPDiQ9Z1Q2.
MaxQBiQ9Z1Q2.
PaxDbiQ9Z1Q2.
PeptideAtlasiQ9Z1Q2.
PRIDEiQ9Z1Q2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000007251; ENSMUSP00000007251; ENSMUSG00000007036.
GeneIDi193742.
KEGGimmu:193742.
UCSCiuc008cfq.1. mouse.

Organism-specific databases

CTDi7920.
MGIiMGI:99476. Abhd16a.

Phylogenomic databases

eggNOGiKOG1553. Eukaryota.
ENOG410XQU4. LUCA.
GeneTreeiENSGT00390000017119.
HOVERGENiHBG050666.
InParanoidiQ9Z1Q2.
OMAiPVDFDVK.
OrthoDBiEOG091G065R.
PhylomeDBiQ9Z1Q2.
TreeFamiTF314267.

Miscellaneous databases

PROiQ9Z1Q2.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000007036.
CleanExiMM_BAT5.
ExpressionAtlasiQ9Z1Q2. baseline and differential.
GenevisibleiQ9Z1Q2. MM.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR000073. AB_hydrolase_1.
IPR026604. ABHD16A.
[Graphical view]
PANTHERiPTHR12277:SF54. PTHR12277:SF54. 1 hit.
PfamiPF00561. Abhydrolase_1. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiABHGA_MOUSE
AccessioniPrimary (citable) accession number: Q9Z1Q2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: January 23, 2007
Last modified: November 2, 2016
This is version 121 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.