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Protein
Submitted name:

Son of sevenless 1

Gene

Sos2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-112412. SOS-mediated signalling.
R-RNO-167044. Signalling to RAS.
R-RNO-2428933. SHC-related events triggered by IGF1R.
R-RNO-74751. Insulin receptor signalling cascade.

Names & Taxonomyi

Protein namesi
Submitted name:
Son of sevenless 1Imported
Gene namesi
Name:Sos2Imported
Synonyms:Sos1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi620435. Sos2.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Proteomic databases

PaxDbiQ9Z1I1.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiQ9Z1I1. 1 interactor.
MINTiMINT-4508448.

Structurei

3D structure databases

ProteinModelPortaliQ9Z1I1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini129 – 204DH (DBL-homology)InterPro annotationAdd BLAST76

Phylogenomic databases

eggNOGiKOG3417. Eukaryota.
ENOG410XR96. LUCA.
HOGENOMiHOG000013040.
HOVERGENiHBG103663.
PhylomeDBiQ9Z1I1.

Family and domain databases

InterProiView protein in InterPro
IPR000219. DH-domain.
IPR009072. Histone-fold.
IPR007125. Histone_H2A/H2B/H3.
PfamiView protein in Pfam
PF00125. Histone. 1 hit.
PF00621. RhoGEF. 1 hit.
SUPFAMiSSF47113. SSF47113. 1 hit.
SSF48065. SSF48065. 1 hit.
PROSITEiView protein in PROSITE
PS50010. DH_2. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q9Z1I1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
EERVQKSFPH PIDKWAIADA QSAIEKRKRR NPLLLPVDKI HPSLKEVLGY
60 70 80 90 100
KVDYHVSLYI VAVLEYISAD ILKLAGNYVF NIRHYEISQQ DIKVSMCADK
110 120 130 140 150
VLMDMFDQDD DIGLVSLCEE EPCSSGELNY YDLVRTEIAE ERQYLRELNM
160 170 180 190 200
IIKVFREAFL SDKKLFKSSE IEKIFSNISD IHELTVKLLG LIEDTVEMTD

EGSP
Length:204
Mass (Da):23,589
Last modified:May 1, 1999 - v1
Checksum:iEA5A123AE610CD52
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei204Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D83014 mRNA. Translation: BAA74949.1.
UniGeneiRn.4226.

Genome annotation databases

UCSCiRGD:620435. rat.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ9Z1I1_RAT
AccessioniPrimary (citable) accession number: Q9Z1I1
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: July 5, 2017
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)