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Q9Z1I1

- Q9Z1I1_RAT

UniProt

Q9Z1I1 - Q9Z1I1_RAT

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Protein
Submitted name:

Son of sevenless 1

Gene

Sos2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. Rho guanyl-nucleotide exchange factor activity Source: InterPro

GO - Biological processi

  1. positive regulation of small GTPase mediated signal transduction Source: RGD
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_204559. SOS-mediated signalling.

Names & Taxonomyi

Protein namesi
Submitted name:
Son of sevenless 1Imported
Gene namesi
Name:Sos2Imported
Synonyms:Sos1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi620435. Sos2.

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: Reactome
  2. protein complex Source: RGD
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ9Z1I1.

Expressioni

Gene expression databases

GenevestigatoriQ9Z1I1.

Interactioni

Protein-protein interaction databases

IntActiQ9Z1I1. 1 interaction.
MINTiMINT-4508448.
STRINGi10116.ENSRNOP00000006425.

Structurei

3D structure databases

ProteinModelPortaliQ9Z1I1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiNOG265981.
HOGENOMiHOG000013040.
HOVERGENiHBG103663.
PhylomeDBiQ9Z1I1.

Family and domain databases

Gene3Di1.10.20.10. 1 hit.
1.20.900.10. 1 hit.
InterProiIPR000219. DH-domain.
IPR009072. Histone-fold.
IPR007125. Histone_core_D.
[Graphical view]
PfamiPF00125. Histone. 1 hit.
PF00621. RhoGEF. 1 hit.
[Graphical view]
SUPFAMiSSF47113. SSF47113. 1 hit.
SSF48065. SSF48065. 1 hit.
PROSITEiPS50010. DH_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9Z1I1-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
EERVQKSFPH PIDKWAIADA QSAIEKRKRR NPLLLPVDKI HPSLKEVLGY
60 70 80 90 100
KVDYHVSLYI VAVLEYISAD ILKLAGNYVF NIRHYEISQQ DIKVSMCADK
110 120 130 140 150
VLMDMFDQDD DIGLVSLCEE EPCSSGELNY YDLVRTEIAE ERQYLRELNM
160 170 180 190 200
IIKVFREAFL SDKKLFKSSE IEKIFSNISD IHELTVKLLG LIEDTVEMTD

EGSP
Length:204
Mass (Da):23,589
Last modified:May 1, 1999 - v1
Checksum:iEA5A123AE610CD52
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei204 – 2041Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D83014 mRNA. Translation: BAA74949.1.
UniGeneiRn.4226.

Genome annotation databases

UCSCiRGD:620435. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D83014 mRNA. Translation: BAA74949.1 .
UniGenei Rn.4226.

3D structure databases

ProteinModelPortali Q9Z1I1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q9Z1I1. 1 interaction.
MINTi MINT-4508448.
STRINGi 10116.ENSRNOP00000006425.

Proteomic databases

PaxDbi Q9Z1I1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

UCSCi RGD:620435. rat.

Organism-specific databases

RGDi 620435. Sos2.

Phylogenomic databases

eggNOGi NOG265981.
HOGENOMi HOG000013040.
HOVERGENi HBG103663.
PhylomeDBi Q9Z1I1.

Enzyme and pathway databases

Reactomei REACT_204559. SOS-mediated signalling.

Gene expression databases

Genevestigatori Q9Z1I1.

Family and domain databases

Gene3Di 1.10.20.10. 1 hit.
1.20.900.10. 1 hit.
InterProi IPR000219. DH-domain.
IPR009072. Histone-fold.
IPR007125. Histone_core_D.
[Graphical view ]
Pfami PF00125. Histone. 1 hit.
PF00621. RhoGEF. 1 hit.
[Graphical view ]
SUPFAMi SSF47113. SSF47113. 1 hit.
SSF48065. SSF48065. 1 hit.
PROSITEi PS50010. DH_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Effect of long-term exercise on gene expression of insulin signaling pathway intermediates in skeletal muscle."
    Kim Y.-B., Inoue T., Nakajima R., Shirai-Morishita Y., Tokuyama K., Suzuki M.
    Biochem. Biophys. Res. Commun. 254:720-727(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Spraque-DawleyImported.
    Tissue: Skeletal muscleImported.

Entry informationi

Entry nameiQ9Z1I1_RAT
AccessioniPrimary (citable) accession number: Q9Z1I1
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: October 29, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)