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Protein
Submitted name:

Cytochrome P-450 2A14

Gene

CYP2A14

Organism
Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

MonooxygenaseUniRule annotation, Oxidoreductase

Keywords - Ligandi

HemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P-450 2A14Imported
Gene namesi
Name:CYP2A14Imported
OrganismiCricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)Imported
Taxonomic identifieri10029 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaCricetidaeCricetinaeCricetulus

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei6 – 2419HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliQ9Z1H8.
SMRiQ9Z1H8. Positions 31-494.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG015789.
KOiK07411.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
IPR008067. Cyt_P450_E_grp-I_CYP2A-like.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR01684. EP450ICYP2A.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9Z1H8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLASGLLLVS VLAFLVILVL MSVWKQRKLS GKMPPGPTPL PFIGNYLQLN
60 70 80 90 100
TAQMYNSLMK ISKRYGPVFT VHLGPRRRIV VLWGQEAVKE ALVDQAEEFS
110 120 130 140 150
GRGEQATFDS FFEGYGLVFS SGERAKQLRR FSIATLRDFG MGKRGVEERI
160 170 180 190 200
LEEAGYLLEA LQKTNGALID PTFYLSRAVS NVMSSIVFGD RFDYEDQEFL
210 220 230 240 250
SLLRMMLETF QFTASSTGQL YEMFSSVMKR LPGPQQQAYK GLKALEDFIA
260 270 280 290 300
KKVEQHQSTL DPNSPRDFID SFLIRMQEEK DPNTEFFMKN LVLTTLNLFA
310 320 330 340 350
AGTETISTTL RYGFLLLMKH PDVEAKVHEE IDRVIGRNRQ PKYEDRTKMP
360 370 380 390 400
YTEAVIHEIQ RFGDVIPMGV PRRVTKDTKF RDFLIPKGTD VFPVLGSVLK
410 420 430 440 450
DSKFFSNPKD FNPKHFLDGN MQFKKNDAFV PFSLGKRYCF GEGLARMELF
460 470 480 490
LFLTIILQNF RFRSSQAPQD IDVSPQLVGF GTLPPNYTMS FLSR
Length:494
Mass (Da):56,425
Last modified:May 1, 1999 - v1
Checksum:i2F98E39E3A058F30
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D86954 mRNA. Translation: BAA34652.1.
RefSeqiNP_001230950.1. NM_001244021.1.

Genome annotation databases

GeneIDi100689033.
KEGGicge:100689033.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D86954 mRNA. Translation: BAA34652.1.
RefSeqiNP_001230950.1. NM_001244021.1.

3D structure databases

ProteinModelPortaliQ9Z1H8.
SMRiQ9Z1H8. Positions 31-494.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100689033.
KEGGicge:100689033.

Organism-specific databases

CTDi100689033.

Phylogenomic databases

HOVERGENiHBG015789.
KOiK07411.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
IPR008067. Cyt_P450_E_grp-I_CYP2A-like.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR01684. EP450ICYP2A.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9Z1H8_CRIGR
AccessioniPrimary (citable) accession number: Q9Z1H8
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: December 9, 2015
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.