Reviewed, UniProtKB/Swiss-Prot Q9Z148 (EHMT2_MOUSE)

Names and origin

Protein names

Recommended name:
    Histone-lysine N-methyltransferase, H3 lysine-9 specific 3
    EC=2.1.1.43
Alternative name(s):
    Histone H3-K9 methyltransferase 3
      Short name=H3-K9-HMTase 3
    Euchromatic histone-lysine N-methyltransferase 2
    HLA-B-associated transcript 8
    Protein G9a

Gene names

Name:	Ehmt2
Synonyms:	Bat8, G9a, Ng36

Organism

Mus musculus (Mouse)

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	1263 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Histone methyltransferase. Preferentially methylates 'Lys-9' of histone H3 and 'Lys-27' of histone H3 (in vitro). H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also methylates histone H1.
Catalytic activity	S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
Subunit structure	Part of the E2F6.com-1 complex in G0 phase composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR, GFI1B, L3MBTL2 and YAF2 By similarity. Interacts with WIZ and EHMT1. Ref.7
Subcellular location	Nucleus. Note: Almost excluded form nucleoli. Associates with euchromatic regions. Does not associate with heterochromatin. Ref.6
Domain	The SET domain mediates interaction with WIZ.
Disruption phenotype	Mice show a higher level of histone H3 with acetylated 'Lys-9' and/or methylated 'Lys-4', display severe developmental defects and die within E9.5-E12.5 stages. Ref.1
Sequence similarities	Belongs to the histone-lysine methyltransferase family. Suvar3-9 subfamily. Contains 7 ANK repeats. Contains 1 post-SET domain. Contains 1 pre-SET domain. Contains 1 SET domain.
Caution	NG36 and G9a were originally thought to derive from two separate genes.
Sequence caution	The sequence AAC84164.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence AAC84165.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Cellular component	Nucleus
Coding sequence diversity	Alternative splicing
Domain	ANK repeat Repeat
Ligand	Metal-binding S-adenosyl-L-methionine Zinc
Molecular function	Chromatin regulator Methyltransferase Transferase
PTM	Phosphoprotein
Gene Ontology (GO)
Biological process	fertilization Inferred from mutant phenotype. Source: MGI histone H3-K9 methylation Inferred from mutant phenotype. Source: MGI negative regulation of transcription from RNA polymerase II promoter Inferred from mutant phenotype. Source: MGI organ growth Inferred from mutant phenotype. Source: MGI pachytene Inferred from mutant phenotype. Source: MGI spermatid development Inferred from mutant phenotype. Source: MGI synaptonemal complex assembly Inferred from mutant phenotype. Source: MGI
Cellular component	nucleus Inferred from direct assay. Source: MGI
Molecular function	histone-lysine N-methyltransferase activity Inferred from electronic annotation. Source: EC zinc ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q9Z148-1)

Also known as: G9a-L;

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q9Z148-2)

Also known as: G9a-S;

The sequence of this isoform differs from the canonical sequence as follows:
     1-57: Missing.
     58-71: AGLTGPPVPCLPSQ → MAAAAGAAAAAAAE
     426-459: Missing.

Isoform 3 (identifier: Q9Z148-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-57: Missing.
     58-71: AGLTGPPVPCLPSQ → MAAAAGAAAAAAAE

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1263	1263	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3		PRO_0000186069
Regions
	Repeat	702 – 731	30	ANK 1
	Repeat	737 – 766	30	ANK 2
	Repeat	770 – 799	30	ANK 3
	Repeat	803 – 833	31	ANK 4
	Repeat	837 – 866	30	ANK 5
	Repeat	870 – 899	30	ANK 6
	Repeat	903 – 932	30	ANK 7
	Domain	1025 – 1088	64	Pre-SET
	Domain	1090 – 1212	123	SET
	Domain	1217 – 1233	17	Post-SET
	Region	1101 – 1103	3	S-adenosyl-L-methionine binding By similarity
	Region	1165 – 1166	2	S-adenosyl-L-methionine binding By similarity
	Compositional bias	352 – 379	28	Poly-Glu
Sites
	Metal binding	1027	1	Zinc 1 By similarity
	Metal binding	1027	1	Zinc 2 By similarity
	Metal binding	1029	1	Zinc 1 By similarity
	Metal binding	1033	1	Zinc 1 By similarity
	Metal binding	1033	1	Zinc 3 By similarity
	Metal binding	1038	1	Zinc 1 By similarity
	Metal binding	1040	1	Zinc 2 By similarity
	Metal binding	1070	1	Zinc 2 By similarity
	Metal binding	1070	1	Zinc 3 By similarity
	Metal binding	1074	1	Zinc 2 By similarity
	Metal binding	1076	1	Zinc 3 By similarity
	Metal binding	1080	1	Zinc 3 By similarity
	Metal binding	1168	1	Zinc 4 By similarity
	Metal binding	1221	1	Zinc 4 By similarity
	Metal binding	1223	1	Zinc 4 By similarity
	Metal binding	1228	1	Zinc 4 By similarity
	Binding site	1138	1	S-adenosyl-L-methionine By similarity
Amino acid modifications
	Modified residue	193	1	Phosphoserine By similarity
	Modified residue	285	1	Phosphoserine By similarity
	Modified residue	298	1	Phosphoserine By similarity
	Modified residue	608	1	Phosphothreonine Ref.8
	Modified residue	1263	1	Phosphothreonine By similarity
Natural variations
	Alternative sequence	1 – 57	57	Missing in isoform 2 and isoform 3.		VSP_002214
	Alternative sequence	58 – 71	14	AGLTG…CLPSQ → MAAAAGAAAAAAAE in isoform 2 and isoform 3.		VSP_002215
	Alternative sequence	426 – 459	34	Missing in isoform 2.		VSP_002216
Experimental info
	Mutagenesis	1162	1	R → H: Strongly reduces histone methyltransferase activity. Ref.6
	Mutagenesis	1165 – 1168	4	Missing: Abolishes histone methyltransferase activity and subsequent repression. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 (G9a-L) [UniParc]. Last modified November 15, 2002. Version 2. Checksum: 74DBFF9A36769589	FASTA	1,263	138,039
	10 20 30 40 50 60 MRGLPRGRGL MRARGRGRAA PTGGRGRGRG GAHRGRGRPR SLLSLPRAQA SWAPQLPAGL 70 80 90 100 110 120 TGPPVPCLPS QGEAPAEMGA LLLEKEPRGA AERVHSSLGD TPQSEETLPK ANPDSLEPAG 130 140 150 160 170 180 PSSPASVTVT VGDEGADTPV GAASLIGDEP ESLEGDGGRI VLGHATKSFP SSPSKGGACP 190 200 210 220 230 240 SRAKMSMTGA GKSPPSVQSL AMRLLSMPGA QGAATAGPEP SPATTAAQEG QPKVHRARKT 250 260 270 280 290 300 MSKPSNGQPP IPEKRPPEVQ HFRMSDDMHL GKVTSDVAKR RKLNSGSLSE DLGSAGGSGD 310 320 330 340 350 360 IILEKGEPRP LEEWETVVGD DFSLYYDAYS VDERVDSDSK SEVEALAEQL SEEEEEEEEE 370 380 390 400 410 420 EEEEEEEEEE EEEEEEDEES GNQSDRSGSS GRRKAKKKWR KDSPWVKPSR KRRKREPPRA 430 440 450 460 470 480 KEPRGVNGVG SSGPSEYMEV PLGSLELPSE GTLSPNHAGV SNDTSSLETE RGFEELPLCS 490 500 510 520 530 540 CRMEAPKIDR ISERAGHKCM ATESVDGELL GCNAAILKRE TMRPSSRVAL MVLCEAHRAR 550 560 570 580 590 600 MVKHHCCPGC GYFCTAGTFL ECHPDFRVAH RFHKACVSQL NGMVFCPHCG EDASEAQEVT 610 620 630 640 650 660 IPRGDGGTPP IGTAAPALPP LAHDAPGRAD TSQPSARMRG HGEPRRPPCD PLADTIDSSG 670 680 690 700 710 720 PSLTLPNGGC LSAVGLPPGP GREALEKALV IQESERRKKL RFHPRQLYLS VKQGELQKVI 730 740 750 760 770 780 LMLLDNLDPN FQSDQQSKRT PLHAAAQKGS VEICHVLLQA GANINAVDKQ QRTPLMEAVV 790 800 810 820 830 840 NNHLEVARYM VQLGGCVYSK EEDGSTCLHH AAKIGNLEMV SLLLSTGQVD VNAQDSGGWT 850 860 870 880 890 900 PIIWAAEHKH IDVIRMLLTR GADVTLTDNE ENICLHWASF TGSAAIAEVL LNAQCDLHAV 910 920 930 940 950 960 NYHGDTPLHI AARESYHDCV LLFLSRGANP ELRNKEGDTA WDLTPERSDV WFALQLNRKL 970 980 990 1000 1010 1020 RLGVGNRAVR TEKIICRDVA RGYENVPIPC VNGVDGEPCP EDYKYISENC ETSTMNIDRN 1030 1040 1050 1060 1070 1080 ITHLQHCTCV DDCSSSNCLC GQLSIRCWYD KDGRLLQEFN KIEPPLIFEC NQACSCWRSC 1090 1100 1110 1120 1130 1140 KNRVVQSGIK VRLQLYRTAK MGWGVRALQT IPQGTFICEY VGELISDAEA DVREDDSYLF 1150 1160 1170 1180 1190 1200 DLDNKDGEVY CIDARYYGNI SRFINHLCDP NIIPVRVFML HQDLRFPRIA FFSSRDIRTG 1210 1220 1230 1240 1250 1260 EELGFDYGDR FWDIKSKYFT CQCGSEKCKH SAEAIALEQS RLARLDPHPE LLPDLSSLPP INT
	Isoform 2 (G9a-S). Checksum: 52D345057AFCF200	FASTA	1,172	128,420
	10 20 30 40 50 60 MAAAAGAAAA AAAEGEAPAE MGALLLEKEP RGAAERVHSS LGDTPQSEET LPKANPDSLE 70 80 90 100 110 120 PAGPSSPASV TVTVGDEGAD TPVGAASLIG DEPESLEGDG GRIVLGHATK SFPSSPSKGG 130 140 150 160 170 180 ACPSRAKMSM TGAGKSPPSV QSLAMRLLSM PGAQGAATAG PEPSPATTAA QEGQPKVHRA 190 200 210 220 230 240 RKTMSKPSNG QPPIPEKRPP EVQHFRMSDD MHLGKVTSDV AKRRKLNSGS LSEDLGSAGG 250 260 270 280 290 300 SGDIILEKGE PRPLEEWETV VGDDFSLYYD AYSVDERVDS DSKSEVEALA EQLSEEEEEE 310 320 330 340 350 360 EEEEEEEEEE EEEEEEEEED EESGNQSDRS GSSGRRKAKK KWRKDSPWVK PSRKRRKREP 370 380 390 400 410 420 PRAKEPRGVS NDTSSLETER GFEELPLCSC RMEAPKIDRI SERAGHKCMA TESVDGELLG 430 440 450 460 470 480 CNAAILKRET MRPSSRVALM VLCEAHRARM VKHHCCPGCG YFCTAGTFLE CHPDFRVAHR 490 500 510 520 530 540 FHKACVSQLN GMVFCPHCGE DASEAQEVTI PRGDGGTPPI GTAAPALPPL AHDAPGRADT 550 560 570 580 590 600 SQPSARMRGH GEPRRPPCDP LADTIDSSGP SLTLPNGGCL SAVGLPPGPG REALEKALVI 610 620 630 640 650 660 QESERRKKLR FHPRQLYLSV KQGELQKVIL MLLDNLDPNF QSDQQSKRTP LHAAAQKGSV 670 680 690 700 710 720 EICHVLLQAG ANINAVDKQQ RTPLMEAVVN NHLEVARYMV QLGGCVYSKE EDGSTCLHHA 730 740 750 760 770 780 AKIGNLEMVS LLLSTGQVDV NAQDSGGWTP IIWAAEHKHI DVIRMLLTRG ADVTLTDNEE 790 800 810 820 830 840 NICLHWASFT GSAAIAEVLL NAQCDLHAVN YHGDTPLHIA ARESYHDCVL LFLSRGANPE 850 860 870 880 890 900 LRNKEGDTAW DLTPERSDVW FALQLNRKLR LGVGNRAVRT EKIICRDVAR GYENVPIPCV 910 920 930 940 950 960 NGVDGEPCPE DYKYISENCE TSTMNIDRNI THLQHCTCVD DCSSSNCLCG QLSIRCWYDK 970 980 990 1000 1010 1020 DGRLLQEFNK IEPPLIFECN QACSCWRSCK NRVVQSGIKV RLQLYRTAKM GWGVRALQTI 1030 1040 1050 1060 1070 1080 PQGTFICEYV GELISDAEAD VREDDSYLFD LDNKDGEVYC IDARYYGNIS RFINHLCDPN 1090 1100 1110 1120 1130 1140 IIPVRVFMLH QDLRFPRIAF FSSRDIRTGE ELGFDYGDRF WDIKSKYFTC QCGSEKCKHS 1150 1160 1170 AEAIALEQSR LARLDPHPEL LPDLSSLPPI NT
	Isoform 3. Checksum: 5DFF4CBADB784977	FASTA	1,206	131,772
	10 20 30 40 50 60 MAAAAGAAAA AAAEGEAPAE MGALLLEKEP RGAAERVHSS LGDTPQSEET LPKANPDSLE 70 80 90 100 110 120 PAGPSSPASV TVTVGDEGAD TPVGAASLIG DEPESLEGDG GRIVLGHATK SFPSSPSKGG 130 140 150 160 170 180 ACPSRAKMSM TGAGKSPPSV QSLAMRLLSM PGAQGAATAG PEPSPATTAA QEGQPKVHRA 190 200 210 220 230 240 RKTMSKPSNG QPPIPEKRPP EVQHFRMSDD MHLGKVTSDV AKRRKLNSGS LSEDLGSAGG 250 260 270 280 290 300 SGDIILEKGE PRPLEEWETV VGDDFSLYYD AYSVDERVDS DSKSEVEALA EQLSEEEEEE 310 320 330 340 350 360 EEEEEEEEEE EEEEEEEEED EESGNQSDRS GSSGRRKAKK KWRKDSPWVK PSRKRRKREP 370 380 390 400 410 420 PRAKEPRGVN GVGSSGPSEY MEVPLGSLEL PSEGTLSPNH AGVSNDTSSL ETERGFEELP 430 440 450 460 470 480 LCSCRMEAPK IDRISERAGH KCMATESVDG ELLGCNAAIL KRETMRPSSR VALMVLCEAH 490 500 510 520 530 540 RARMVKHHCC PGCGYFCTAG TFLECHPDFR VAHRFHKACV SQLNGMVFCP HCGEDASEAQ 550 560 570 580 590 600 EVTIPRGDGG TPPIGTAAPA LPPLAHDAPG RADTSQPSAR MRGHGEPRRP PCDPLADTID 610 620 630 640 650 660 SSGPSLTLPN GGCLSAVGLP PGPGREALEK ALVIQESERR KKLRFHPRQL YLSVKQGELQ 670 680 690 700 710 720 KVILMLLDNL DPNFQSDQQS KRTPLHAAAQ KGSVEICHVL LQAGANINAV DKQQRTPLME 730 740 750 760 770 780 AVVNNHLEVA RYMVQLGGCV YSKEEDGSTC LHHAAKIGNL EMVSLLLSTG QVDVNAQDSG 790 800 810 820 830 840 GWTPIIWAAE HKHIDVIRML LTRGADVTLT DNEENICLHW ASFTGSAAIA EVLLNAQCDL 850 860 870 880 890 900 HAVNYHGDTP LHIAARESYH DCVLLFLSRG ANPELRNKEG DTAWDLTPER SDVWFALQLN 910 920 930 940 950 960 RKLRLGVGNR AVRTEKIICR DVARGYENVP IPCVNGVDGE PCPEDYKYIS ENCETSTMNI 970 980 990 1000 1010 1020 DRNITHLQHC TCVDDCSSSN CLCGQLSIRC WYDKDGRLLQ EFNKIEPPLI FECNQACSCW 1030 1040 1050 1060 1070 1080 RSCKNRVVQS GIKVRLQLYR TAKMGWGVRA LQTIPQGTFI CEYVGELISD AEADVREDDS 1090 1100 1110 1120 1130 1140 YLFDLDNKDG EVYCIDARYY GNISRFINHL CDPNIIPVRV FMLHQDLRFP RIAFFSSRDI 1150 1160 1170 1180 1190 1200 RTGEELGFDY GDRFWDIKSK YFTCQCGSEK CKHSAEAIAL EQSRLARLDP HPELLPDLSS LPPINT

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis." Tachibana M., Sugimoto K., Nozaki M., Ueda J., Ohta T., Ohki M., Fukuda M., Takeda N., Niida H., Kato H., Shinkai Y. Genes Dev. 16:1779-1791(2002) [PubMed: 12130538] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), MUTAGENESIS OF 1165-ASN--CYS-1168, DISRUPTION PHENOTYPE.
[2]	"Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse." Xie T., Rowen L., Aguado B., Ahearn M.E., Madan A., Qin S., Campbell R.D., Hood L. Genome Res. 13:2621-2636(2003) [PubMed: 14656967] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 129.
[3]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed: 19468303] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6.
[4]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3). Tissue: Mammary tumor.
[5]	"Novel NG36/G9a gene products encoded within the human and mouse MHC class III regions." Brown S.E., Campbell R.D., Sanderson C.M. Mamm. Genome 12:916-924(2001) [PubMed: 11707778] [Abstract] Cited for: ALTERNATIVE SPLICING (ISOFORM 2).
[6]	"Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3." Tachibana M., Sugimoto K., Fukushima T., Shinkai Y. J. Biol. Chem. 276:25309-25317(2001) [PubMed: 11316813] [Abstract] Cited for: ENZYME ACTIVITY, SUBCELLULAR LOCATION, MUTAGENESIS OF ARG-1162.
[7]	"Zinc finger protein Wiz links G9a/GLP histone methyltransferases to the co-repressor molecule CtBP." Ueda J., Tachibana M., Ikura T., Shinkai Y. J. Biol. Chem. 281:20120-20128(2006) [PubMed: 16702210] [Abstract] Cited for: INTERACTION WITH WIZ AND EHMT1.
[8]	"Large-scale phosphorylation analysis of mouse liver." Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007) [PubMed: 17242355] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-608, MASS SPECTROMETRY. Tissue: Liver.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF109906 Genomic DNA. Translation: AAC84164.1. Sequence problems. AF109906 Genomic DNA. Translation: AAC84165.1. Sequence problems. AB077209 mRNA. Translation: BAC05482.1. AB077210 mRNA. Translation: BAC05483.1. CT025759 Genomic DNA. Translation: CAM27791.1. BC025539 mRNA. Translation: AAH25539.1. Different initiation. BC058357 mRNA. Translation: AAH58357.1. Different initiation.
IPI	IPI00170261. IPI00230523. IPI00515297.
RefSeq	NP_665829.1. NP_671493.1.
UniGene	Mm.35345
3D structure databases
SMR	Q9Z148. Positions 678-943, 706-948, 735-961, 975-1245.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-46358N. DIP-46359N.
IntAct	Q9Z148. 3 interactions.
STRING	Q9Z148.
PTM databases
PhosphoSite	Q9Z148.
Proteomic databases
PRIDE	Q9Z148.
Genome annotation databases
Ensembl	ENSMUST00000013931; ENSMUSP00000013931; ENSMUSG00000013787; Mus musculus. [Genome view] ENSMUST00000078061; ENSMUSP00000077208; ENSMUSG00000013787; Mus musculus. [Genome view] ENSMUST00000114033; ENSMUSP00000109667; ENSMUSG00000013787; Mus musculus. [Genome view]
GeneID	110147.
KEGG	mmu:110147.
UCSC	uc008ceb.1. mouse. uc008cec.1. mouse. uc008ced.1. mouse.
Organism-specific databases
CTD	110147.
MGI	MGI:2148922. Ehmt2.
Phylogenomic databases
HOVERGEN	Q9Z148.
PhylomeDB	Q9Z148.
Enzyme and pathway databases
BRENDA	2.1.1.43. 244.
Gene expression databases
ArrayExpress	Q9Z148.
Bgee	Q9Z148.
CleanEx	MM_EHMT2.
Genevestigator	Q9Z148.
GermOnline	ENSMUSG00000013787. Mus musculus.
Family and domain databases
InterPro	IPR002110. Ankyrin_rpt. IPR020683. Ankyrin_rpt-contain_dom. IPR003616. Post-SET_dom. IPR007728. Pre-SET_dom. IPR003606. Pre-SET_Zn_bd_sub. IPR001214. SET_dom. [Graphical view]
Gene3D	G3DSA:1.25.40.20. ANK. 1 hit.
Pfam	PF00023. Ank. 4 hits. PF05033. Pre-SET. 1 hit. PF00856. SET. 1 hit. [Graphical view]
SMART	SM00248. ANK. 6 hits. SM00508. PostSET. 1 hit. SM00468. PreSET. 1 hit. SM00317. SET. 1 hit. [Graphical view]
PROSITE	PS50297. ANK_REP_REGION. 1 hit. PS50088. ANK_REPEAT. 5 hits. PS50868. POST_SET. False negative. PS50867. PRE_SET. 1 hit. PS50280. SET. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	363413.
SOURCE	Search...

Entry information

Entry name

EHMT2_MOUSE

Accession

Primary (citable) accession number: Q9Z148
Secondary accession number(s): A2CG75 , Q6PE08, Q8K4R6, Q8K4R7, Q9Z149

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 15, 2002
Last sequence update:	November 15, 2002
Last modified:	February 9, 2010
This is version 94 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)