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Protein

Galectin-2

Gene

Lgals2

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

This protein binds beta-galactoside. Its physiological function is not yet known.

GO - Molecular functioni

  • carbohydrate binding Source: UniProtKB-KW
  • galactoside binding Source: RGD

Keywordsi

LigandLectin

Names & Taxonomyi

Protein namesi
Recommended name:
Galectin-2
Short name:
Gal-2
Gene namesi
Name:Lgals2
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 7

Organism-specific databases

RGDi621269. Lgals2.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000769271 – 130Galectin-2Add BLAST130

Proteomic databases

PaxDbiQ9Z144.

PTM databases

iPTMnetiQ9Z144.
PhosphoSitePlusiQ9Z144.

Expressioni

Gene expression databases

BgeeiENSRNOG00000008539.
GenevisibleiQ9Z144. RN.

Interactioni

Subunit structurei

Homodimer.

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000011750.

Structurei

3D structure databases

ProteinModelPortaliQ9Z144.
SMRiQ9Z144.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 130GalectinPROSITE-ProRule annotationAdd BLAST127

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni65 – 71Beta-galactoside bindingSequence analysis7

Phylogenomic databases

eggNOGiKOG3587. Eukaryota.
ENOG4111EA0. LUCA.
GeneTreeiENSGT00440000034263.
HOGENOMiHOG000059539.
HOVERGENiHBG006255.
InParanoidiQ9Z144.
KOiK10090.
OMAiLNLHFNP.
OrthoDBiEOG091G0S7H.
PhylomeDBiQ9Z144.
TreeFamiTF315551.

Family and domain databases

CDDicd00070. GLECT. 1 hit.
InterProiView protein in InterPro
IPR013320. ConA-like_dom.
IPR001079. Galectin_CRD.
PfamiView protein in Pfam
PF00337. Gal-bind_lectin. 1 hit.
SMARTiView protein in SMART
SM00908. Gal-bind_lectin. 1 hit.
SM00276. GLECT. 1 hit.
SUPFAMiSSF49899. SSF49899. 1 hit.
PROSITEiView protein in PROSITE
PS51304. GALECTIN. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9Z144-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEKFEVTNL NMKSGMSLKI KGKIHNDVNS FTINLGQGKE TLNLHFNPRF
60 70 80 90 100
NESTIVCNTL DGSSWGQEQR ENHSCFSPGS EVKLTLTFQD KDFKVTLPDG
110 120 130
HSLTFPNRLG HNHLRYLSMD GLQISSFKLE
Length:130
Mass (Da):14,733
Last modified:May 1, 1999 - v1
Checksum:iE4641D804C9CA7E0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB001075 mRNA. Translation: BAA74954.1.
RefSeqiNP_598283.1. NM_133599.1.
UniGeneiRn.2982.

Genome annotation databases

EnsembliENSRNOT00000011750; ENSRNOP00000011750; ENSRNOG00000008539.
GeneIDi171134.
KEGGirno:171134.
UCSCiRGD:621269. rat.

Similar proteinsi

Entry informationi

Entry nameiLEG2_RAT
AccessioniPrimary (citable) accession number: Q9Z144
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: May 1, 1999
Last modified: September 27, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome