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Protein

Immunoglobulin superfamily member 6

Gene

Igsf6

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Miscellaneous

This gene is coded entirely within the intron of Mettl9 which is transcribed in the opposite strand of the DNA.

Names & Taxonomyi

Protein namesi
Recommended name:
Immunoglobulin superfamily member 6
Short name:
IgSF6
Alternative name(s):
Protein DORA
Gene namesi
Name:Igsf6
Synonyms:Dora
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi620663 Igsf6

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini28 – 153ExtracellularSequence analysisAdd BLAST126
Transmembranei154 – 174HelicalSequence analysisAdd BLAST21
Topological domaini175 – 238CytoplasmicSequence analysisAdd BLAST64

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_500006501528 – 238Immunoglobulin superfamily member 6Add BLAST211

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi51 ↔ 118PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiQ9Z0K5
PRIDEiQ9Z0K5

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000023262

Structurei

3D structure databases

ProteinModelPortaliQ9Z0K5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 134Ig-like C2-typeAdd BLAST105

Keywords - Domaini

Immunoglobulin domain, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IUPA Eukaryota
ENOG410Z30T LUCA
HOGENOMiHOG000113019
HOVERGENiHBG098510
InParanoidiQ9Z0K5
PhylomeDBiQ9Z0K5

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
IPR013106 Ig_V-set
PfamiView protein in Pfam
PF07686 V-set, 1 hit
SMARTiView protein in SMART
SM00409 IG, 1 hit
SM00406 IGv, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9Z0K5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGPVSTSRRG LRLGISLILL QVGVVGACTV SVLQPGYLEV DYTSQTVTME
60 70 80 90 100
CTFSTTGCPA VQPKSLWFRC GTHQPEALCL DGCRNEADKF TVKETLDQNR
110 120 130 140 150
VSLTVNRLSP NDSAIYICGI AFPNEPVPTA KQTGDGTTLV VRERLFSREV
160 170 180 190 200
HSLLIVLLAL LAVYVTGVCV IFIVLFRSKS NTPRSRETKE DSKKKSARRI
210 220 230
FQEIAQELYH KRYVETSHQP EQDGNYENRK ALPSPGRP
Length:238
Mass (Da):26,433
Last modified:May 1, 1999 - v1
Checksum:i02C661D53755DECC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ223184 mRNA Translation: CAA11156.1
RefSeqiNP_598226.1, NM_133542.2
UniGeneiRn.204094

Genome annotation databases

GeneIDi171064
KEGGirno:171064
UCSCiRGD:620663 rat

Similar proteinsi

Entry informationi

Entry nameiIGSF6_RAT
AccessioniPrimary (citable) accession number: Q9Z0K5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: May 1, 1999
Last modified: May 23, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health