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Protein

Immunoglobulin superfamily member 6

Gene

Igsf6

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Immunoglobulin superfamily member 6
Short name:
IgSF6
Alternative name(s):
Protein DORA
Gene namesi
Name:Igsf6
Synonyms:Dora
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi620663. Igsf6.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini28 – 153ExtracellularSequence analysisAdd BLAST126
Transmembranei154 – 174HelicalSequence analysisAdd BLAST21
Topological domaini175 – 238CytoplasmicSequence analysisAdd BLAST64

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_500006501528 – 238Immunoglobulin superfamily member 6Add BLAST211

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi51 ↔ 118PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiQ9Z0K5.
PRIDEiQ9Z0K5.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000023262.

Structurei

3D structure databases

ProteinModelPortaliQ9Z0K5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 134Ig-like C2-typeAdd BLAST105

Sequence similaritiesi

Keywords - Domaini

Immunoglobulin domain, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IUPA. Eukaryota.
ENOG410Z30T. LUCA.
HOGENOMiHOG000113019.
HOVERGENiHBG098510.
InParanoidiQ9Z0K5.
PhylomeDBiQ9Z0K5.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 1 hit.
SM00406. IGv. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9Z0K5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGPVSTSRRG LRLGISLILL QVGVVGACTV SVLQPGYLEV DYTSQTVTME
60 70 80 90 100
CTFSTTGCPA VQPKSLWFRC GTHQPEALCL DGCRNEADKF TVKETLDQNR
110 120 130 140 150
VSLTVNRLSP NDSAIYICGI AFPNEPVPTA KQTGDGTTLV VRERLFSREV
160 170 180 190 200
HSLLIVLLAL LAVYVTGVCV IFIVLFRSKS NTPRSRETKE DSKKKSARRI
210 220 230
FQEIAQELYH KRYVETSHQP EQDGNYENRK ALPSPGRP
Length:238
Mass (Da):26,433
Last modified:May 1, 1999 - v1
Checksum:i02C661D53755DECC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ223184 mRNA. Translation: CAA11156.1.
RefSeqiNP_598226.1. NM_133542.2.
UniGeneiRn.204094.

Genome annotation databases

GeneIDi171064.
KEGGirno:171064.
UCSCiRGD:620663. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ223184 mRNA. Translation: CAA11156.1.
RefSeqiNP_598226.1. NM_133542.2.
UniGeneiRn.204094.

3D structure databases

ProteinModelPortaliQ9Z0K5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000023262.

Proteomic databases

PaxDbiQ9Z0K5.
PRIDEiQ9Z0K5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi171064.
KEGGirno:171064.
UCSCiRGD:620663. rat.

Organism-specific databases

CTDi10261.
RGDi620663. Igsf6.

Phylogenomic databases

eggNOGiENOG410IUPA. Eukaryota.
ENOG410Z30T. LUCA.
HOGENOMiHOG000113019.
HOVERGENiHBG098510.
InParanoidiQ9Z0K5.
PhylomeDBiQ9Z0K5.

Miscellaneous databases

PROiQ9Z0K5.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 1 hit.
SM00406. IGv. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiIGSF6_RAT
AccessioniPrimary (citable) accession number: Q9Z0K5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: May 1, 1999
Last modified: June 8, 2016
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Miscellaneous

This gene is coded entirely within the intron of Mettl9 which is transcribed in the opposite strand of the DNA.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.