Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

CUGBP Elav-like family member 2

Gene

Celf2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing (By similarity). Specifically activates exon 5 inclusion of TNNT2 in embryonic, but not adult, skeletal muscle (By similarity). Activates TNNT2 exon 5 inclusion by antagonizing the repressive effect of PTB (By similarity). Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon but exclusion of the non-muscle (NM) exon in actinin pre-mRNAs (By similarity). Promotes inclusion of exonS 21 and exclusion of exon 5 of the NMDA receptor R1 pre-mRNA (By similarity). Involved in the apoB RNA editing activity (By similarity). Increases COX2 mRNA stability and inhibits COX2 mRNA translation in epithelial cells after radiation injury. Modulates the cellular apoptosis program by regulating COX2-mediated prostaglandin E2 (PGE2) expression. Binds to (CUG)n triplet repeats in the 3'-UTR of transcripts such as DMPK (By similarity). Binds to the muscle-specific splicing enhancer (MSE) intronic sites flanking the TNNT2 alternative exon 5 (By similarity). Binds preferentially to UG-rich sequences, in particular UG repeat and UGUU motifs (By similarity). Binds to apoB mRNA, specifically to AU-rich sequences located immediatly upstream of the edited cytidine (By similarity). Binds AU-rich sequences in the 3'-UTR of COX2 mRNA. Binds to an intronic RNA element responsible for the silencing of exon 21 splicing. Binds to (CUG)n repeats.By similarity3 Publications

GO - Molecular functioni

GO - Biological processi

  • mRNA splice site selection Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

Repressor

Keywords - Biological processi

mRNA processing

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
CUGBP Elav-like family member 2
Short name:
CELF-2
Alternative name(s):
Bruno-like protein 3
CUG triplet repeat RNA-binding protein 2
Short name:
CUG-BP2
CUG-BP- and ETR-3-like factor 2
ELAV-type RNA-binding protein 3
Short name:
ETR-3
Short name:
mETR-3
Neuroblastoma apoptosis-related RNA-binding protein
Short name:
mNapor
RNA-binding protein BRUNOL-3
Gene namesi
Name:Celf2
Synonyms:Cugbp2, Napor
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:1338822. Celf2.

Subcellular locationi

  • Nucleus
  • Cytoplasm

  • Note: Colocalizes with APOBEC1 and A1CF (By similarity). RNA-binding activity is detected in both nuclear and cytoplasmic compartments (By similarity). Accumulates in the cytoplasm after ionizing radiation.By similarity

GO - Cellular componenti

  • cytoplasm Source: MGI
  • nucleus Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 508508CUGBP Elav-like family member 2PRO_0000295190Add
BLAST

Proteomic databases

MaxQBiQ9Z0H4.
PaxDbiQ9Z0H4.
PeptideAtlasiQ9Z0H4.
PRIDEiQ9Z0H4.

PTM databases

iPTMnetiQ9Z0H4.
PhosphoSiteiQ9Z0H4.

Expressioni

Tissue specificityi

Expressed in tongue, spleen and brain (at protein level). Expressed in liver, thigh, stomach, lung and heart to very low levels (at protein level). Expressed in heart, brain, lung and muscle.4 Publications

Developmental stagei

Expressed in heart, muscle, brain, liver, thigh, stomach and lung at 14 dpc (at protein level). Expressed in embryo at 7, 11 and 17 dpc. Expressed in the developing central nervous system from 12 to 16 dpc.2 Publications

Inductioni

Up-regulated following ionizing radiation in the crypt epithelial cells of the intestin. Down-regulated by bacterial lipopolysaccharides (LPS). Down-regulated by prostaglandin E2 following ionizing radiation.2 Publications

Gene expression databases

BgeeiENSMUSG00000002107.
CleanExiMM_CUGBP2.
ExpressionAtlasiQ9Z0H4. baseline and differential.
GenevisibleiQ9Z0H4. MM.

Interactioni

Subunit structurei

Interacts with A1CF.By similarity

Protein-protein interaction databases

IntActiQ9Z0H4. 1 interaction.
MINTiMINT-4131235.
STRINGi10090.ENSMUSP00000110574.

Structurei

3D structure databases

ProteinModelPortaliQ9Z0H4.
SMRiQ9Z0H4. Positions 6-211, 388-508.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini40 – 12384RRM 1PROSITE-ProRule annotationAdd
BLAST
Domaini132 – 21281RRM 2PROSITE-ProRule annotationAdd
BLAST
Domaini423 – 50179RRM 3PROSITE-ProRule annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni1 – 283283Necessary for RNA-binding, TNNT2 exon 5 and NMDA R1 exon 21 inclusionBy similarityAdd
BLAST
Regioni357 – 508152Necessary for RNA-binding, TNNT2 exon 5 and NMDA R1 exon 21 inclusionBy similarityAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi284 – 397114Ala-richAdd
BLAST

Sequence similaritiesi

Belongs to the CELF/BRUNOL family.Curated
Contains 3 RRM (RNA recognition motif) domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG0146. Eukaryota.
ENOG410XNTW. LUCA.
GeneTreeiENSGT00560000076837.
HOVERGENiHBG107646.
InParanoidiQ9Z0H4.
KOiK13207.
OMAiRTSELAF.
OrthoDBiEOG091G19O1.
PhylomeDBiQ9Z0H4.
TreeFamiTF314924.

Family and domain databases

Gene3Di3.30.70.330. 3 hits.
InterProiIPR002343. Hud_Sxl_RNA.
IPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00076. RRM_1. 3 hits.
[Graphical view]
PRINTSiPR00961. HUDSXLRNA.
SMARTiSM00360. RRM. 3 hits.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 3 hits.
PROSITEiPS50102. RRM. 3 hits.
[Graphical view]

Sequences (10)i

Sequence statusi: Complete.

This entry describes 10 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q9Z0H4-1) [UniParc]FASTAAdd to basket
Also known as: Napor-3

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MRCPKSAVTM RNEELLLSNG TANKMNGALD HSDQPDPDAI KMFVGQIPRS
60 70 80 90 100
WSEKELKELF EPYGAVYQIN VLRDRSQNPP QSKGCCFVTF YTRKAALEAQ
110 120 130 140 150
NALHNIKTLP GMHHPIQMKP ADSEKSNAVE DRKLFIGMVS KKCNENDIRV
160 170 180 190 200
MFSPFGQIEE CRILRGPDGL SRGCAFVTFS TRAMAQNAIK AMHQSQTMEG
210 220 230 240 250
CSSPIVVKFA DTQKDKEQRR LQQQLAQQMQ QLNTATWGNL TGLGGLTPQY
260 270 280 290 300
LALLQQATSS SNLGAFSGIQ QMAGMNALQL QNLATLAAAA AAAQTSATST
310 320 330 340 350
NANPLSSTSS ALGALTSPVA ASTPNSTAGA AMNSLTSLGT LQGLAGATVG
360 370 380 390 400
LNNINALAGM AALNGGLGAT GLTNGTAGTM DALTQAYSGI QQYAAAALPT
410 420 430 440 450
LYSQSLLQQQ SAAGSQKEGP EGANLFIYHL PQEFGDQDIL QMFMPFGNVI
460 470 480 490 500
SAKVFIDKQT NLSKCFGFVS YDNPVSAQAA IQAMNGFQIG MKRLKVQLKR

SKNDSKPY
Length:508
Mass (Da):54,271
Last modified:May 1, 1999 - v1
Checksum:iC35CBEF598749A79
GO
Isoform 2 (identifier: Q9Z0H4-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-17: MRCPKSAVTMRNEELLL → MVSLISDLDSLRGWKALRETATELSGSPP

Show »
Length:520
Mass (Da):55,410
Checksum:iD953BE720659AA40
GO
Isoform 3 (identifier: Q9Z0H4-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-274: Missing.
     359-359: G → GTINS

Show »
Length:238
Mass (Da):24,288
Checksum:iB481A9789044F18D
GO
Isoform 4 (identifier: Q9Z0H4-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-24: Missing.
     358-358: A → AVAQMLS

Show »
Length:490
Mass (Da):52,254
Checksum:iE83296A0F13D90BE
GO
Isoform 5 (identifier: Q9Z0H4-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-24: Missing.
     359-359: G → GTINS

Show »
Length:488
Mass (Da):52,040
Checksum:i6CED374F47024FCD
GO
Isoform 6 (identifier: Q9Z0H4-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-17: MRCPKSAVTMRNEELLL → MVSLISDLDSLRGWKALRETATELSGSPP
     359-359: G → GTINS

Show »
Length:524
Mass (Da):55,825
Checksum:iF410C2916232026B
GO
Isoform 7 (identifier: Q9Z0H4-7) [UniParc]FASTAAdd to basket
Also known as: Napor-1

The sequence of this isoform differs from the canonical sequence as follows:
     1-24: Missing.

Show »
Length:484
Mass (Da):51,625
Checksum:i5C63F3D4F7203E56
GO
Isoform 8 (identifier: Q9Z0H4-8) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     359-359: G → GTINS

Show »
Length:512
Mass (Da):54,686
Checksum:i3F0C1FB0483D02EC
GO
Isoform 9 (identifier: Q9Z0H4-9) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MFERTSELAFVETISVESM

Note: Gene prediction based on similarity to rat ortholog. No experimental confirmation available.
Show »
Length:526
Mass (Da):56,328
Checksum:i8852489573C931B4
GO
Isoform 11 (identifier: Q9Z0H4-11) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     359-359: G → GTINS
     419-466: Missing.

Show »
Length:464
Mass (Da):49,254
Checksum:i5F95C63D5FF253D2
GO

Sequence cautioni

The sequence BAE31371 differs from that shown. Reason: Erroneous initiation. Curated
Isoform 7 : The sequence CAA77110 differs from that shown. Reason: Frameshift at positions 395 and 415. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti218 – 2181Q → K in CAA77110 (PubMed:9887331).Curated
Sequence conflicti245 – 2451G → E in CAA77110 (PubMed:9887331).Curated
Sequence conflicti420 – 4201P → T in BAE30715 (PubMed:16141072).Curated
Sequence conflicti420 – 4201P → T in BAE31857 (PubMed:16141072).Curated

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 274274Missing in isoform 3. 1 PublicationVSP_026801Add
BLAST
Alternative sequencei1 – 2424Missing in isoform 4, isoform 5 and isoform 7. 3 PublicationsVSP_026802Add
BLAST
Alternative sequencei1 – 1717MRCPK…EELLL → MVSLISDLDSLRGWKALRET ATELSGSPP in isoform 2 and isoform 6. 1 PublicationVSP_026803Add
BLAST
Alternative sequencei1 – 11M → MFERTSELAFVETISVESM in isoform 9. CuratedVSP_026804
Alternative sequencei358 – 3581A → AVAQMLS in isoform 4. 1 PublicationVSP_026805
Alternative sequencei359 – 3591G → GTINS in isoform 3, isoform 5, isoform 6, isoform 8 and isoform 11. 1 PublicationVSP_026806
Alternative sequencei419 – 46648Missing in isoform 11. 1 PublicationVSP_026808Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF090696 mRNA. Translation: AAD13763.1.
AF090697 mRNA. Translation: AAD13764.1.
Y18298 mRNA. Translation: CAA77110.1. Frameshift.
AK137292 mRNA. Translation: BAE23295.1.
AK151818 mRNA. Translation: BAE30715.1.
AK152628 mRNA. Translation: BAE31371.1. Different initiation.
AK153267 mRNA. Translation: BAE31857.1.
AK160861 mRNA. Translation: BAE36053.1.
AK161349 mRNA. Translation: BAE36341.1.
AK164914 mRNA. Translation: BAE37963.1.
AL929240, AL845492, AL845515 Genomic DNA. Translation: CAM18466.1.
AL845515, AL845492, AL929240 Genomic DNA. Translation: CAM18813.1.
AL845515, AL845492 Genomic DNA. Translation: CAM18816.1.
AL845515, AL845492 Genomic DNA. Translation: CAM18817.1.
AL845515, AL845492 Genomic DNA. Translation: CAM18818.1.
AL845492, AL845515, AL929240 Genomic DNA. Translation: CAM46032.1.
AL845492, AL845515 Genomic DNA. Translation: CAM46034.1.
AL845492, AL845515 Genomic DNA. Translation: CAM46035.1.
AL845492, AL845515 Genomic DNA. Translation: CAM46036.1.
BC026856 mRNA. Translation: AAH26856.1.
CCDSiCCDS50491.1. [Q9Z0H4-7]
CCDS50492.1. [Q9Z0H4-4]
CCDS50494.1. [Q9Z0H4-9]
CCDS59633.1. [Q9Z0H4-2]
RefSeqiNP_001103698.1. NM_001110228.1. [Q9Z0H4-9]
NP_001103699.1. NM_001110229.1. [Q9Z0H4-6]
NP_001103700.1. NM_001110230.1. [Q9Z0H4-2]
NP_001103701.1. NM_001110231.1. [Q9Z0H4-4]
NP_001103702.1. NM_001110232.1. [Q9Z0H4-7]
NP_001153764.1. NM_001160292.1.
NP_001153765.1. NM_001160293.1. [Q9Z0H4-9]
NP_001297376.1. NM_001310447.1.
NP_034290.2. NM_010160.2.
XP_006497400.1. XM_006497337.2. [Q9Z0H4-9]
UniGeneiMm.398543.

Genome annotation databases

EnsembliENSMUST00000002176; ENSMUSP00000002176; ENSMUSG00000002107. [Q9Z0H4-7]
ENSMUST00000100429; ENSMUSP00000097996; ENSMUSG00000002107. [Q9Z0H4-7]
ENSMUST00000114924; ENSMUSP00000110574; ENSMUSG00000002107. [Q9Z0H4-9]
ENSMUST00000114927; ENSMUSP00000110577; ENSMUSG00000002107. [Q9Z0H4-5]
ENSMUST00000114934; ENSMUSP00000110584; ENSMUSG00000002107. [Q9Z0H4-9]
ENSMUST00000142941; ENSMUSP00000120459; ENSMUSG00000002107. [Q9Z0H4-4]
ENSMUST00000150624; ENSMUSP00000138297; ENSMUSG00000002107. [Q9Z0H4-5]
ENSMUST00000182706; ENSMUSP00000138764; ENSMUSG00000002107. [Q9Z0H4-2]
ENSMUST00000182851; ENSMUSP00000138363; ENSMUSG00000002107. [Q9Z0H4-1]
GeneIDi14007.
KEGGimmu:14007.
UCSCiuc008ign.2. mouse. [Q9Z0H4-3]
uc008igp.2. mouse. [Q9Z0H4-4]
uc008igq.3. mouse. [Q9Z0H4-11]
uc008igr.3. mouse. [Q9Z0H4-9]
uc008igs.3. mouse. [Q9Z0H4-2]
uc008igt.3. mouse. [Q9Z0H4-6]
uc008igv.3. mouse. [Q9Z0H4-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF090696 mRNA. Translation: AAD13763.1.
AF090697 mRNA. Translation: AAD13764.1.
Y18298 mRNA. Translation: CAA77110.1. Frameshift.
AK137292 mRNA. Translation: BAE23295.1.
AK151818 mRNA. Translation: BAE30715.1.
AK152628 mRNA. Translation: BAE31371.1. Different initiation.
AK153267 mRNA. Translation: BAE31857.1.
AK160861 mRNA. Translation: BAE36053.1.
AK161349 mRNA. Translation: BAE36341.1.
AK164914 mRNA. Translation: BAE37963.1.
AL929240, AL845492, AL845515 Genomic DNA. Translation: CAM18466.1.
AL845515, AL845492, AL929240 Genomic DNA. Translation: CAM18813.1.
AL845515, AL845492 Genomic DNA. Translation: CAM18816.1.
AL845515, AL845492 Genomic DNA. Translation: CAM18817.1.
AL845515, AL845492 Genomic DNA. Translation: CAM18818.1.
AL845492, AL845515, AL929240 Genomic DNA. Translation: CAM46032.1.
AL845492, AL845515 Genomic DNA. Translation: CAM46034.1.
AL845492, AL845515 Genomic DNA. Translation: CAM46035.1.
AL845492, AL845515 Genomic DNA. Translation: CAM46036.1.
BC026856 mRNA. Translation: AAH26856.1.
CCDSiCCDS50491.1. [Q9Z0H4-7]
CCDS50492.1. [Q9Z0H4-4]
CCDS50494.1. [Q9Z0H4-9]
CCDS59633.1. [Q9Z0H4-2]
RefSeqiNP_001103698.1. NM_001110228.1. [Q9Z0H4-9]
NP_001103699.1. NM_001110229.1. [Q9Z0H4-6]
NP_001103700.1. NM_001110230.1. [Q9Z0H4-2]
NP_001103701.1. NM_001110231.1. [Q9Z0H4-4]
NP_001103702.1. NM_001110232.1. [Q9Z0H4-7]
NP_001153764.1. NM_001160292.1.
NP_001153765.1. NM_001160293.1. [Q9Z0H4-9]
NP_001297376.1. NM_001310447.1.
NP_034290.2. NM_010160.2.
XP_006497400.1. XM_006497337.2. [Q9Z0H4-9]
UniGeneiMm.398543.

3D structure databases

ProteinModelPortaliQ9Z0H4.
SMRiQ9Z0H4. Positions 6-211, 388-508.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9Z0H4. 1 interaction.
MINTiMINT-4131235.
STRINGi10090.ENSMUSP00000110574.

PTM databases

iPTMnetiQ9Z0H4.
PhosphoSiteiQ9Z0H4.

Proteomic databases

MaxQBiQ9Z0H4.
PaxDbiQ9Z0H4.
PeptideAtlasiQ9Z0H4.
PRIDEiQ9Z0H4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000002176; ENSMUSP00000002176; ENSMUSG00000002107. [Q9Z0H4-7]
ENSMUST00000100429; ENSMUSP00000097996; ENSMUSG00000002107. [Q9Z0H4-7]
ENSMUST00000114924; ENSMUSP00000110574; ENSMUSG00000002107. [Q9Z0H4-9]
ENSMUST00000114927; ENSMUSP00000110577; ENSMUSG00000002107. [Q9Z0H4-5]
ENSMUST00000114934; ENSMUSP00000110584; ENSMUSG00000002107. [Q9Z0H4-9]
ENSMUST00000142941; ENSMUSP00000120459; ENSMUSG00000002107. [Q9Z0H4-4]
ENSMUST00000150624; ENSMUSP00000138297; ENSMUSG00000002107. [Q9Z0H4-5]
ENSMUST00000182706; ENSMUSP00000138764; ENSMUSG00000002107. [Q9Z0H4-2]
ENSMUST00000182851; ENSMUSP00000138363; ENSMUSG00000002107. [Q9Z0H4-1]
GeneIDi14007.
KEGGimmu:14007.
UCSCiuc008ign.2. mouse. [Q9Z0H4-3]
uc008igp.2. mouse. [Q9Z0H4-4]
uc008igq.3. mouse. [Q9Z0H4-11]
uc008igr.3. mouse. [Q9Z0H4-9]
uc008igs.3. mouse. [Q9Z0H4-2]
uc008igt.3. mouse. [Q9Z0H4-6]
uc008igv.3. mouse. [Q9Z0H4-1]

Organism-specific databases

CTDi10659.
MGIiMGI:1338822. Celf2.

Phylogenomic databases

eggNOGiKOG0146. Eukaryota.
ENOG410XNTW. LUCA.
GeneTreeiENSGT00560000076837.
HOVERGENiHBG107646.
InParanoidiQ9Z0H4.
KOiK13207.
OMAiRTSELAF.
OrthoDBiEOG091G19O1.
PhylomeDBiQ9Z0H4.
TreeFamiTF314924.

Miscellaneous databases

ChiTaRSiCelf2. mouse.
PROiQ9Z0H4.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000002107.
CleanExiMM_CUGBP2.
ExpressionAtlasiQ9Z0H4. baseline and differential.
GenevisibleiQ9Z0H4. MM.

Family and domain databases

Gene3Di3.30.70.330. 3 hits.
InterProiIPR002343. Hud_Sxl_RNA.
IPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00076. RRM_1. 3 hits.
[Graphical view]
PRINTSiPR00961. HUDSXLRNA.
SMARTiSM00360. RRM. 3 hits.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 3 hits.
PROSITEiPS50102. RRM. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCELF2_MOUSE
AccessioniPrimary (citable) accession number: Q9Z0H4
Secondary accession number(s): A2AS10
, A2AS11, A2AS15, Q3TNX4, Q3TTI4, Q3TUB8, Q3U668, Q3U7J8, Q3U9F2, Q3UVH4, Q9R0B2, Q9Z187
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: May 1, 1999
Last modified: September 7, 2016
This is version 131 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.