Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Zinc finger and BTB domain-containing protein 22

Gene

Zbtb22

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri483 – 50422C2H2-type 1; atypicalPROSITE-ProRule annotationAdd
BLAST
Zinc fingeri510 – 53223C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri538 – 55922C2H2-type 3PROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger and BTB domain-containing protein 22
Alternative name(s):
Protein BING1
Zinc finger protein 297
Gene namesi
Name:Zbtb22
Synonyms:Bing1, Zfp297, Znf297
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:1931870. Zbtb22.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 638638Zinc finger and BTB domain-containing protein 22PRO_0000047518Add
BLAST

Proteomic databases

MaxQBiQ9Z0G7.
PaxDbiQ9Z0G7.
PRIDEiQ9Z0G7.

PTM databases

iPTMnetiQ9Z0G7.
PhosphoSiteiQ9Z0G7.

Expressioni

Gene expression databases

BgeeiQ9Z0G7.
ExpressionAtlasiQ9Z0G7. baseline and differential.
GenevisibleiQ9Z0G7. MM.

Interactioni

Protein-protein interaction databases

BioGridi219885. 2 interactions.
STRINGi10090.ENSMUSP00000057466.

Structurei

3D structure databases

ProteinModelPortaliQ9Z0G7.
SMRiQ9Z0G7. Positions 29-147, 473-582.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini57 – 12165BTBPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 BTB (POZ) domain.PROSITE-ProRule annotation
Contains 3 C2H2-type zinc fingers.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri483 – 50422C2H2-type 1; atypicalPROSITE-ProRule annotationAdd
BLAST
Zinc fingeri510 – 53223C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri538 – 55922C2H2-type 3PROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00760000119063.
HOGENOMiHOG000231975.
HOVERGENiHBG056510.
InParanoidiQ9Z0G7.
KOiK10502.
OMAiVEMGFSG.
OrthoDBiEOG7HTHH3.
PhylomeDBiQ9Z0G7.

Family and domain databases

Gene3Di3.30.160.60. 2 hits.
InterProiIPR000210. BTB/POZ_dom.
IPR011333. SKP1/BTB/POZ.
IPR029833. ZBT22/43.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PANTHERiPTHR24414:SF4. PTHR24414:SF4. 3 hits.
PfamiPF00651. BTB. 1 hit.
[Graphical view]
SMARTiSM00225. BTB. 1 hit.
SM00355. ZnF_C2H2. 3 hits.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
PROSITEiPS50097. BTB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 1 hit.
PS50157. ZINC_FINGER_C2H2_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9Z0G7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPSALSPSG ATLPLPLSLA PPPLPLPAAA VVHVSFPEVT SALLESLNQQ
60 70 80 90 100
RLQGQLCDVS IRVQGREFRA HRAVLAASSP YFHDQVLLKG MTSISLPSVM
110 120 130 140 150
DPGAFETVLA SAYTGRLSMA AADIVNFLTV GSVLQMWHIV DKCTELLREG
160 170 180 190 200
RSAATTTTVT TAAAPSVSVP CASVPSGNGG TVAPATVGSV RSHTSSRASE
210 220 230 240 250
NQSPSSSNYF SPRESTDFSS TSQDAFVASA AGSGNRRDGG PVFPAPVVGS
260 270 280 290 300
AGTTSGKLLL EADELCDDGG DGRGAVAPGA GLRRSNCMPA SAVPQKHWVY
310 320 330 340 350
VKQARNCPAP ASLVHQDPDL EDEEEEEDLV LTCEDDEDEE MGGGSGVPAG
360 370 380 390 400
GEPEATLSIS DVRTLTEPAD KGEEQVNFCE SSNDFGPYEG GGAGAGLDDP
410 420 430 440 450
GGPTPSSYAL THPPRPLLPL DVPGNQILVF PSSSSQAPGQ PPGNTAEHGA
460 470 480 490 500
VTLGGTSAVG LGIPSGSGGA PGGTGNSDGN KIFLCHCGKA FSHKSMRDRH
510 520 530 540 550
VNMHLNLRPF DCPVCNKKFK MKHHLTEHMK THTGLKPYEC SVCAKKFMWR
560 570 580 590 600
DSFMRHRGHC ERRHRMGVGG VGSGPGPGPG PGTPSGPALQ PKRESSTVGG
610 620 630
GSGDEANSAT PPSHRRVWSP PSVHKVEMDF SGGGGAAH
Length:638
Mass (Da):66,029
Last modified:May 1, 1999 - v1
Checksum:i40343A4C6CB5EF6C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF110520 Genomic DNA. Translation: AAC97972.1.
AF100956 Genomic DNA. Translation: AAC69892.1.
BC026964 mRNA. Translation: AAH26964.1.
BC052154 mRNA. Translation: AAH52154.1.
CCDSiCCDS28634.1.
RefSeqiNP_065650.1. NM_020625.3.
XP_006525241.1. XM_006525178.2.
XP_006525505.1. XM_006525442.2.
XP_006536773.1. XM_006536710.2.
XP_006537504.1. XM_006537441.2.
UniGeneiMm.482096.

Genome annotation databases

EnsembliENSMUST00000053429; ENSMUSP00000057466; ENSMUSG00000051390.
GeneIDi81630.
KEGGimmu:81630.
UCSCiuc008cac.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF110520 Genomic DNA. Translation: AAC97972.1.
AF100956 Genomic DNA. Translation: AAC69892.1.
BC026964 mRNA. Translation: AAH26964.1.
BC052154 mRNA. Translation: AAH52154.1.
CCDSiCCDS28634.1.
RefSeqiNP_065650.1. NM_020625.3.
XP_006525241.1. XM_006525178.2.
XP_006525505.1. XM_006525442.2.
XP_006536773.1. XM_006536710.2.
XP_006537504.1. XM_006537441.2.
UniGeneiMm.482096.

3D structure databases

ProteinModelPortaliQ9Z0G7.
SMRiQ9Z0G7. Positions 29-147, 473-582.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi219885. 2 interactions.
STRINGi10090.ENSMUSP00000057466.

PTM databases

iPTMnetiQ9Z0G7.
PhosphoSiteiQ9Z0G7.

Proteomic databases

MaxQBiQ9Z0G7.
PaxDbiQ9Z0G7.
PRIDEiQ9Z0G7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000053429; ENSMUSP00000057466; ENSMUSG00000051390.
GeneIDi81630.
KEGGimmu:81630.
UCSCiuc008cac.1. mouse.

Organism-specific databases

CTDi9278.
MGIiMGI:1931870. Zbtb22.

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00760000119063.
HOGENOMiHOG000231975.
HOVERGENiHBG056510.
InParanoidiQ9Z0G7.
KOiK10502.
OMAiVEMGFSG.
OrthoDBiEOG7HTHH3.
PhylomeDBiQ9Z0G7.

Miscellaneous databases

ChiTaRSiZbtb22. mouse.
PROiQ9Z0G7.
SOURCEiSearch...

Gene expression databases

BgeeiQ9Z0G7.
ExpressionAtlasiQ9Z0G7. baseline and differential.
GenevisibleiQ9Z0G7. MM.

Family and domain databases

Gene3Di3.30.160.60. 2 hits.
InterProiIPR000210. BTB/POZ_dom.
IPR011333. SKP1/BTB/POZ.
IPR029833. ZBT22/43.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PANTHERiPTHR24414:SF4. PTHR24414:SF4. 3 hits.
PfamiPF00651. BTB. 1 hit.
[Graphical view]
SMARTiSM00225. BTB. 1 hit.
SM00355. ZnF_C2H2. 3 hits.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
PROSITEiPS50097. BTB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 1 hit.
PS50157. ZINC_FINGER_C2H2_2. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Sequence of the mouse major histocompatibility complex class II region."
    Rowen L., Qin S., Madan A., Loretz C., James R., Dors M., Mix L., Hall J., Lasky S., Hood L.
    Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 129/SvJ.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J and FVB/N.
    Tissue: Embryo and Kidney.

Entry informationi

Entry nameiZBT22_MOUSE
AccessioniPrimary (citable) accession number: Q9Z0G7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 19, 2002
Last sequence update: May 1, 1999
Last modified: June 8, 2016
This is version 133 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.