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Protein

Zinc finger and BTB domain-containing protein 22

Gene

Zbtb22

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri483 – 504C2H2-type 1; atypicalPROSITE-ProRule annotationAdd BLAST22
Zinc fingeri510 – 532C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri538 – 559C2H2-type 3PROSITE-ProRule annotationAdd BLAST22

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger and BTB domain-containing protein 22
Alternative name(s):
Protein BING1
Zinc finger protein 297
Gene namesi
Name:Zbtb22
Synonyms:Bing1, Zfp297, Znf297
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:1931870 Zbtb22

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000475181 – 638Zinc finger and BTB domain-containing protein 22Add BLAST638

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei203PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ9Z0G7
PRIDEiQ9Z0G7

PTM databases

iPTMnetiQ9Z0G7
PhosphoSitePlusiQ9Z0G7

Expressioni

Gene expression databases

BgeeiENSMUSG00000051390
ExpressionAtlasiQ9Z0G7 baseline and differential
GenevisibleiQ9Z0G7 MM

Interactioni

Protein-protein interaction databases

BioGridi219885, 3 interactors
IntActiQ9Z0G7, 1 interactor
STRINGi10090.ENSMUSP00000057466

Structurei

3D structure databases

ProteinModelPortaliQ9Z0G7
SMRiQ9Z0G7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini57 – 121BTBPROSITE-ProRule annotationAdd BLAST65

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri483 – 504C2H2-type 1; atypicalPROSITE-ProRule annotationAdd BLAST22
Zinc fingeri510 – 532C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri538 – 559C2H2-type 3PROSITE-ProRule annotationAdd BLAST22

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00760000119063
HOGENOMiHOG000231975
HOVERGENiHBG056510
InParanoidiQ9Z0G7
KOiK10502
OMAiEPPDKGE
OrthoDBiEOG091G06Z9
PhylomeDBiQ9Z0G7

Family and domain databases

InterProiView protein in InterPro
IPR000210 BTB/POZ_dom
IPR011333 SKP1/BTB/POZ_sf
IPR029833 ZBT22
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PANTHERiPTHR24414:SF4 PTHR24414:SF4, 1 hit
PfamiView protein in Pfam
PF00651 BTB, 1 hit
SMARTiView protein in SMART
SM00225 BTB, 1 hit
SM00355 ZnF_C2H2, 3 hits
SUPFAMiSSF54695 SSF54695, 1 hit
SSF57667 SSF57667, 1 hit
PROSITEiView protein in PROSITE
PS50097 BTB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 1 hit
PS50157 ZINC_FINGER_C2H2_2, 3 hits

Sequencei

Sequence statusi: Complete.

Q9Z0G7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPSALSPSG ATLPLPLSLA PPPLPLPAAA VVHVSFPEVT SALLESLNQQ
60 70 80 90 100
RLQGQLCDVS IRVQGREFRA HRAVLAASSP YFHDQVLLKG MTSISLPSVM
110 120 130 140 150
DPGAFETVLA SAYTGRLSMA AADIVNFLTV GSVLQMWHIV DKCTELLREG
160 170 180 190 200
RSAATTTTVT TAAAPSVSVP CASVPSGNGG TVAPATVGSV RSHTSSRASE
210 220 230 240 250
NQSPSSSNYF SPRESTDFSS TSQDAFVASA AGSGNRRDGG PVFPAPVVGS
260 270 280 290 300
AGTTSGKLLL EADELCDDGG DGRGAVAPGA GLRRSNCMPA SAVPQKHWVY
310 320 330 340 350
VKQARNCPAP ASLVHQDPDL EDEEEEEDLV LTCEDDEDEE MGGGSGVPAG
360 370 380 390 400
GEPEATLSIS DVRTLTEPAD KGEEQVNFCE SSNDFGPYEG GGAGAGLDDP
410 420 430 440 450
GGPTPSSYAL THPPRPLLPL DVPGNQILVF PSSSSQAPGQ PPGNTAEHGA
460 470 480 490 500
VTLGGTSAVG LGIPSGSGGA PGGTGNSDGN KIFLCHCGKA FSHKSMRDRH
510 520 530 540 550
VNMHLNLRPF DCPVCNKKFK MKHHLTEHMK THTGLKPYEC SVCAKKFMWR
560 570 580 590 600
DSFMRHRGHC ERRHRMGVGG VGSGPGPGPG PGTPSGPALQ PKRESSTVGG
610 620 630
GSGDEANSAT PPSHRRVWSP PSVHKVEMDF SGGGGAAH
Length:638
Mass (Da):66,029
Last modified:May 1, 1999 - v1
Checksum:i40343A4C6CB5EF6C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF110520 Genomic DNA Translation: AAC97972.1
AF100956 Genomic DNA Translation: AAC69892.1
BC026964 mRNA Translation: AAH26964.1
BC052154 mRNA Translation: AAH52154.1
CCDSiCCDS28634.1
RefSeqiNP_065650.1, NM_020625.3
UniGeneiMm.482096

Genome annotation databases

EnsembliENSMUST00000053429; ENSMUSP00000057466; ENSMUSG00000051390
GeneIDi81630
KEGGimmu:81630
UCSCiuc008cac.1 mouse

Similar proteinsi

Entry informationi

Entry nameiZBT22_MOUSE
AccessioniPrimary (citable) accession number: Q9Z0G7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 19, 2002
Last sequence update: May 1, 1999
Last modified: March 28, 2018
This is version 147 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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