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Q9YXL6 (Q9YXL6_9INFA) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
RNA-directed RNA polymerase catalytic subunit RuleBase RU004330

EC=2.7.7.48 RuleBase RU004330
Gene names
Name:PB1 EMBL AAC63451.1
OrganismInfluenza A virus H3N2 EMBL AAC63451.1
Taxonomic identifier41857 [NCBI]
Taxonomic lineageVirusesssRNA negative-strand virusesOrthomyxoviridaeInfluenzavirus A

Protein attributes

Sequence length757 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). RuleBase RU004330 SAAS SAAS007099

Sequence similarities

Contains RdRp catalytic domain. SAAS SAAS007099

Sequences

Sequence LengthMass (Da)Tools
Q9YXL6 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: 9AEE58B338AA8BC2

FASTA75786,340
        10         20         30         40         50         60 
MDVNPTLLFL KVPAQNAIST TFPYTGDPPY SHGTGTGYTM DTVNRTHQYS EKGKWTTNTE 

        70         80         90        100        110        120 
TGAPQLNPID GPLPEDNEPS GYAQTDCVLE AMAFLEESHP GIFENSCLET MEVVQQTRVD 

       130        140        150        160        170        180 
KLTQGRQTYD WTLNRNQPAA TALANTIEVF RSNGLTASES GRLIDFLKDV MESMDKEEIE 

       190        200        210        220        230        240 
VTTHFQRKRR VRDNMTKKMV TQRTIGKKKQ RVNKRSYLIR ALTLNTMTKD AERGKLKRRA 

       250        260        270        280        290        300 
IATPGMQIRG FVYFVETLAR SICEKLEQSG LPVGGNEKKA KLANVVRKMM TNSQDTELSF 

       310        320        330        340        350        360 
TITGDNTKWN ENQNPRMFLA MITYITKNQP EWFRNILSIA PIMFSNKMAR LGKGYMFESK 

       370        380        390        400        410        420 
RMKLRTQIPA EMLASIDLKY FNESTRKKIE KIRPLLIDGT ASLSPGMMMG MFNMLSTVLG 

       430        440        450        460        470        480 
VSILNLGQKK YTKTTYWWDG LQSSDDFALI VNAPNHEGIQ AGVDRFYRTC KLVGINMSKK 

       490        500        510        520        530        540 
KSYINKTGTF EFTSFFYRYG FVANFSMELP SFGVSGVNES ADMSIGVTVI KNNMINNDLG 

       550        560        570        580        590        600 
PATAQMALQL FIKDYRYTYR CHRGDTQIQT RRSFELKKLW DQTQSKAGLL VSDGGPNLYN 

       610        620        630        640        650        660 
IRNLHIPEVC LKWELMDEDY RGRLCNPLNP FVSHKEIESV NNAVVMPAHG PAKSMEYDAV 

       670        680        690        700        710        720 
ATTHSWIPKR NRSILNTSQR GILEDEQMYQ KCCNLFEKFF PSSSYRRPVG ISSMVEAMVS 

       730        740        750 
RARIDARIDF ESGRIKKEEF SEIMKICSTI EELRRQK 

« Hide

References

[1]"Phylogenetic analysis of the entire genome of influenza A (H3N2) viruses from Japan: evidence for genetic reassortment of the six internal genes."
Lindstrom S.E., Hiromoto Y., Nerome R., Omoe K., Sugita S., Yamazaki Y., Takahashi T., Nerome K.
J. Virol. 72:8021-8031(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: A/Niigata/137/96 EMBL AAC63451.1.
[2]"Cross-allele cytotoxic T lymphocyte responses against 2009 pandemic H1N1 influenza A virus among HLA-A24 and HLA-A3 supertype-positive individuals."
Liu J., Zhang S., Tan S., Yi Y., Wu B., Cao B., Zhu F., Wang C., Wang H., Qi J., Gao G.F.
J. Virol. 86:13281-13294(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS) OF 498-505.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF037420 Genomic RNA. Translation: AAC63451.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4F7PX-ray1.90C496-505[»]
4F7TX-ray1.70C/F498-505[»]
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR007099. RNA-dir_pol_NSvirus.
IPR001407. RNA_pol_PB1_influenza.
[Graphical view]
PfamPF00602. Flu_PB1. 1 hit.
[Graphical view]
PIRSFPIRSF000827. RdRPol_OMV. 1 hit.
PROSITEPS50525. RDRP_SSRNA_NEG_SEG. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ9YXL6_9INFA
AccessionPrimary (citable) accession number: Q9YXL6
Entry history
Integrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: July 9, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)