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Q9YXL3

- Q9YXL3_9INFA

UniProt

Q9YXL3 - Q9YXL3_9INFA

Protein
Submitted name:

PA polymerase subunit

Gene

PA

Organism
Influenza A virus H3N2
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 1 (01 May 1999)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. RNA binding Source: InterPro
    2. RNA-directed RNA polymerase activity Source: InterPro

    GO - Biological processi

    1. transcription, DNA-templated Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    PA polymerase subunitImported
    Gene namesi
    Name:PAImported
    OrganismiInfluenza A virus H3N2Imported
    Taxonomic identifieri41857 [NCBI]
    Taxonomic lineageiVirusesssRNA negative-strand virusesOrthomyxoviridaeInfluenzavirus A

    Interactioni

    Subunit structurei

    Influenza RNA polymerase is composed of three subunits: PB1, PB2 and PA.SAAS annotation

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4F7MX-ray2.40C/F649-658[»]
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    InterProiIPR001009. RNA-dir_pol_influenzavirus.
    [Graphical view]
    PfamiPF00603. Flu_PA. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9YXL3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEDFVRQCFN PMIVELAEKA MKEYGEDLKI ETNKFAAICT HLEVCFMYSD    50
    FHFINEQGES IVVELDDPNA LLKHRFEIIE GRDRTMAWTV VNSICNTTGA 100
    EKPKFLPDLY DYKENRFIEI GVTRREVHIY YLEKANKIKS ENTHIHIFSF 150
    TGEEMATKAD YTLDEESRAR IKTRLFTIRQ EMANRGLWDS FRQSERGEET 200
    IEEKFEISGT MRRLADQSLP PNFSCLENFR AYVDGFEPNG CIEGKLSQMS 250
    KEVNAKIEPF LKTTPRPIKL PNGPPCYQRS KFLLMDALKL SIEDPSHEGE 300
    GIPLYDAIKC IRTFFGWKEP YIVKPHEKGI NSNYLLSWKQ VLAELQDIET 350
    EEKIPRTKNM KKTSQLKWAL GENMAPEKVD FDNCRDISDL KQYDSDEPEL 400
    RSLSSWIQNE FNKACELTDS IWIELDEIGE DIAPIEHIAS MRRNYFTAEV 450
    SHCRATEYIM KGVYINTALL NASCAAMDDF QLIPMISKCR TKEGRRKTNL 500
    YGFIIKGRSH LRNDTDVVNF VSMEFSLTDP RLEPHKWEKY CVLEIGDMLL 550
    RSAIGQMSRP MFLYVRTNGT SKIKMKWGME MRRCLLQSLQ QIESMIEAES 600
    SVKEKDMTKE FFENKSEAWP IGESPKGVEE GSIGKVCRTL LAKSVFNSLY 650
    ASPQLEGFSA ESRKLLLVVQ ALRDNLEPGT FDLGGLYEAI EECLINDPWV 700
    LLNASWFNSF LKHALK 716
    Length:716
    Mass (Da):82,765
    Last modified:May 1, 1999 - v1
    Checksum:i1F2D03926A52ACCD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF037425 Genomic RNA. Translation: AAC63456.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF037425 Genomic RNA. Translation: AAC63456.1 .

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4F7M X-ray 2.40 C/F 649-658 [» ]
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR001009. RNA-dir_pol_influenzavirus.
    [Graphical view ]
    Pfami PF00603. Flu_PA. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Phylogenetic analysis of the entire genome of influenza A (H3N2) viruses from Japan: evidence for genetic reassortment of the six internal genes."
      Lindstrom S.E., Hiromoto Y., Nerome R., Omoe K., Sugita S., Yamazaki Y., Takahashi T., Nerome K.
      J. Virol. 72:8021-8031(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: A/Tochigi/44/95Imported.
    2. "Cross-allele cytotoxic T lymphocyte responses against 2009 pandemic H1N1 influenza A virus among HLA-A24 and HLA-A3 supertype-positive individuals."
      Liu J., Zhang S., Tan S., Yi Y., Wu B., Cao B., Zhu F., Wang C., Wang H., Qi J., Gao G.F.
      J. Virol. 86:13281-13294(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS) OF 649-658.

    Entry informationi

    Entry nameiQ9YXL3_9INFA
    AccessioniPrimary (citable) accession number: Q9YXL3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 1, 1999
    Last sequence update: May 1, 1999
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3