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Q9YXL3

- Q9YXL3_9INFA

UniProt

Q9YXL3 - Q9YXL3_9INFA

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Protein
Submitted name:

PA polymerase subunit

Gene

PA

Organism
Influenza A virus H3N2
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. RNA binding Source: InterPro
  2. RNA-directed RNA polymerase activity Source: InterPro

GO - Biological processi

  1. transcription, DNA-templated Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
PA polymerase subunitImported
Gene namesi
Name:PAImported
OrganismiInfluenza A virus H3N2Imported
Taxonomic identifieri41857 [NCBI]
Taxonomic lineageiVirusesssRNA negative-strand virusesOrthomyxoviridaeInfluenzavirus A

Interactioni

Subunit structurei

Influenza RNA polymerase is composed of three subunits: PB1, PB2 and PA.SAAS annotation

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4F7MX-ray2.40C/F649-658[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

InterProiIPR001009. RNA-dir_pol_influenzavirus.
[Graphical view]
PfamiPF00603. Flu_PA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9YXL3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEDFVRQCFN PMIVELAEKA MKEYGEDLKI ETNKFAAICT HLEVCFMYSD
60 70 80 90 100
FHFINEQGES IVVELDDPNA LLKHRFEIIE GRDRTMAWTV VNSICNTTGA
110 120 130 140 150
EKPKFLPDLY DYKENRFIEI GVTRREVHIY YLEKANKIKS ENTHIHIFSF
160 170 180 190 200
TGEEMATKAD YTLDEESRAR IKTRLFTIRQ EMANRGLWDS FRQSERGEET
210 220 230 240 250
IEEKFEISGT MRRLADQSLP PNFSCLENFR AYVDGFEPNG CIEGKLSQMS
260 270 280 290 300
KEVNAKIEPF LKTTPRPIKL PNGPPCYQRS KFLLMDALKL SIEDPSHEGE
310 320 330 340 350
GIPLYDAIKC IRTFFGWKEP YIVKPHEKGI NSNYLLSWKQ VLAELQDIET
360 370 380 390 400
EEKIPRTKNM KKTSQLKWAL GENMAPEKVD FDNCRDISDL KQYDSDEPEL
410 420 430 440 450
RSLSSWIQNE FNKACELTDS IWIELDEIGE DIAPIEHIAS MRRNYFTAEV
460 470 480 490 500
SHCRATEYIM KGVYINTALL NASCAAMDDF QLIPMISKCR TKEGRRKTNL
510 520 530 540 550
YGFIIKGRSH LRNDTDVVNF VSMEFSLTDP RLEPHKWEKY CVLEIGDMLL
560 570 580 590 600
RSAIGQMSRP MFLYVRTNGT SKIKMKWGME MRRCLLQSLQ QIESMIEAES
610 620 630 640 650
SVKEKDMTKE FFENKSEAWP IGESPKGVEE GSIGKVCRTL LAKSVFNSLY
660 670 680 690 700
ASPQLEGFSA ESRKLLLVVQ ALRDNLEPGT FDLGGLYEAI EECLINDPWV
710
LLNASWFNSF LKHALK
Length:716
Mass (Da):82,765
Last modified:May 1, 1999 - v1
Checksum:i1F2D03926A52ACCD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF037425 Genomic RNA. Translation: AAC63456.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF037425 Genomic RNA. Translation: AAC63456.1 .

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4F7M X-ray 2.40 C/F 649-658 [» ]
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR001009. RNA-dir_pol_influenzavirus.
[Graphical view ]
Pfami PF00603. Flu_PA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Phylogenetic analysis of the entire genome of influenza A (H3N2) viruses from Japan: evidence for genetic reassortment of the six internal genes."
    Lindstrom S.E., Hiromoto Y., Nerome R., Omoe K., Sugita S., Yamazaki Y., Takahashi T., Nerome K.
    J. Virol. 72:8021-8031(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: A/Tochigi/44/95Imported.
  2. "Cross-allele cytotoxic T lymphocyte responses against 2009 pandemic H1N1 influenza A virus among HLA-A24 and HLA-A3 supertype-positive individuals."
    Liu J., Zhang S., Tan S., Yi Y., Wu B., Cao B., Zhu F., Wang C., Wang H., Qi J., Gao G.F.
    J. Virol. 86:13281-13294(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS) OF 649-658.

Entry informationi

Entry nameiQ9YXL3_9INFA
AccessioniPrimary (citable) accession number: Q9YXL3
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: October 1, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported

External Data

Dasty 3