Q9YUC8 (CAPSD_BFDV) Reviewed, UniProtKB/Swiss-Prot
Last modified February 19, 2014. Version 49. History...
Names and origin
|Protein names||Recommended name:|
|Organism||Beak and feather disease virus (BFDV) [Complete proteome]|
|Taxonomic identifier||77856 [NCBI]|
|Taxonomic lineage||Viruses › ssDNA viruses › Circoviridae › Circovirus|
|Virus host||Gracula [TaxID: 116991]|
Psittaciformes [TaxID: 9223]
|Sequence length||247 AA.|
|Protein existence||Evidence at protein level|
General annotation (Comments)
Self-assembles to form the virion icosahedral capsid with a T=1 symmetry. This very small capsid (17 - 22 nm in diameter) allows the virus to be very stable in the environment and resistant to some disinfectants, including detergents. Essential for the initial attachment to heparan sulfate moities and chondroitin sulfate B of the host cell surface proteoglycans. After attachment, the virus is endocytosed and traffics to the nucleus. The capsid protein binds and transports the viral genome and Rep across the nuclear envelope. Ref.2
Homomultimer. Assembles in the nucleus, presumably in an immature form, then migrates to the cytoplasm once assembled as mature virion By similarity. Interacts with Rep; this interaction relocates Rep into the nucleus. Ref.2
Belongs to the circoviridae capsid protein family.
Sequence annotation (Features)
|||"Psittacine beak and feather disease virus nucleotide sequence analysis and its relationship to porcine circovirus, plant circoviruses, and chicken anaemia virus."|
Bassami M.R., Berryman D., Wilcox G.E., Raidal S.R.
Virology 249:453-459(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
|||"The capsid protein of beak and feather disease virus binds to the viral DNA and is responsible for transporting the replication-associated protein into the nucleus."|
Heath L., Williamson A.L., Rybicki E.P.
J. Virol. 80:7219-7225(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, SUBCELLULAR LOCATION, INTERACTION WITH REP, DNA-BINDING.
|AF080560 Genomic DNA. Translation: AAC69862.1.|
3D structure databases
Protocols and materials databases
Family and domain databases
|InterPro||IPR003383. Circovirus_capsid. |
|Pfam||PF02443. Circo_capsid. 1 hit. |
|Accession||Primary (citable) accession number: Q9YUC8|
|Entry status||Reviewed (UniProtKB/Swiss-Prot)|
|Annotation program||Viral Protein Annotation Program|
Index of protein domains and families