Q9YPD6 (PTASE_MBVLF) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative serine protease
EC=3.4.21.-

Gene names

ORF Names:

ORF2

Organism

Mushroom bacilliform virus (isolate Australia/AUS LF-1) (MBV) [Reference proteome]

Taxonomic identifier

650482 [NCBI]

Taxonomic lineage

Viruses › ssRNA viruses › ssRNA positive-strand viruses, no DNA stage › Barnaviridae › Barnavirus › Mushroom bacilliform virus

Virus host

Agaricus bisporus (White button mushroom) [TaxID: 5341]

Protein attributes

Sequence length	657 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Putative serine protease Potential.
Subcellular location	Host membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the peptidase S39B family.

Ontologies

Keywords
Cellular component	Host membrane Membrane
Domain	Transmembrane Transmembrane helix
Molecular function	Hydrolase Protease Serine protease
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	proteolysis Inferred from electronic annotation. Source: UniProtKB-KW viral reproductive process Inferred from electronic annotation. Source: InterPro
Cellular_component	host cell membrane Inferred from electronic annotation. Source: UniProtKB-SubCell integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	serine-type endopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 657	657	Putative serine protease		PRO_0000402445
Regions
	Transmembrane	4 – 24	21	Helical; Potential
	Transmembrane	46 – 62	17	Helical; Potential
	Transmembrane	109 – 131	23	Helical; Potential
	Compositional bias	550 – 554	5	Poly-Arg
Sites
	Active site	284	1	By similarity
	Active site	300	1	By similarity
	Active site	386	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9YPD6 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: A55C331F24675888	FASTA	657	73,415
	10 20 30 40 50 60 MSKYLATSVR LCLMVCIVGW LLMPSYKELD GWCSSLSSLE RDKSNWLLTG LSTWFCIVPS 70 80 90 100 110 120 GTDQSSLVSY FSPLEKLSKF VQDLDLDFVK LWWLETITLI NTLNTTEKLL SGVTFSVVLW 130 140 150 160 170 180 YPRILVTVLM LVWKLWFPVR FLVVASSLLC LRILVWPFEV IADVILETCA WFTRKYHKLM 190 200 210 220 230 240 DVIEDLMMIP QRVMEWCSGN TAKMVVPTVA SCVSESIESK LDRILMALGR KGTVLEAAQP 250 260 270 280 290 300 GSDFVECEQW PNGLVAIRRH DGRIVGMGFL VVLNGKWRLV TAAHVARECK RGIMLSAGID 310 320 330 340 350 360 SKTVTFQDLD VVLQTQVDAC IMNVPAGTAA SLGVRKVVIN RTPSESKVVR TYGYNSGKFC 370 380 390 400 410 420 MSEGLVGTTS ANMGFRHGCS TLRGWSGTPI YRDNKVVGIH SRCNGIYENF GLSLDLLVGR 430 440 450 460 470 480 LESEETDRYA RTMEEFNTED RPVTPPMEFS WEFEEKFERV RSTRKSFARI ESEVATFTAT 490 500 510 520 530 540 KLSGFDWTDD APMDFDELPV FESTMVSVFQ ERPLGGLPIS NGNKAEEKKI TSEALEPSKS 550 560 570 580 590 600 STPEAAKHTR RRRRNKKKSK NSETGHGPEE QSQQQSRPSS PIPDDSAPVS SPPVSPPSTG 610 620 630 640 650 SVPKSWTQAY TQKLVLLLGS MDGQSKEKVD LAILEAKSFA SALFPPSKPK SSEESEK

References

[1]	"The nucleotide sequence and genome organization of mushroom bacilliform virus: a single-stranded RNA virus of Agaricus bisporus (Lange) Imbach." Revill P.A., Davidson A.D., Wright P.J. Virology 202:904-911(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	U07551 Genomic RNA. Translation: AAA53089.1.
RefSeq	NP_042509.1. NC_001633.1.
3D structure databases
ProteinModelPortal	Q9YPD6.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1497108.
Family and domain databases
InterPro	IPR000382. Peptidase_S39B_luteovirus. IPR009003. Trypsin-like_Pept_dom. [Graphical view]
Pfam	PF02122. Peptidase_S39. 1 hit. [Graphical view]
SUPFAM	SSF50494. Pept_Ser_Cys. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PTASE_MBVLF

Accession

Primary (citable) accession number: Q9YPD6

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 30, 2010
Last sequence update:	May 1, 1999
Last modified:	April 3, 2013
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program