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Protein

P2X purinoceptor

Gene

P2XCE

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Receptor for ATP that acts as a ligand-gated ion channel.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ion channelUniRule annotation, ReceptorUniRule annotationImported

Keywords - Biological processi

Ion transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
P2X purinoceptorUniRule annotation
Gene namesi
Name:P2XCEImported
Synonyms:P2X4Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

Subcellular locationi

  • Membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei30 – 5021HelicalUniRule annotationAdd
BLAST
Transmembranei339 – 36123HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ9YI70.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000006190.

Family & Domainsi

Sequence similaritiesi

Belongs to the P2X receptor family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiENOG410IFJF. Eukaryota.
ENOG410XR0C. LUCA.
HOGENOMiHOG000232042.
HOVERGENiHBG053086.
KOiK05218.
PhylomeDBiQ9YI70.

Family and domain databases

Gene3Di2.60.490.10. 1 hit.
InterProiIPR003047. P2X4_purnocptor.
IPR027309. P2X_extracellular_dom.
IPR001429. P2X_purnocptor.
[Graphical view]
PANTHERiPTHR10125. PTHR10125. 1 hit.
PTHR10125:SF18. PTHR10125:SF18. 1 hit.
PfamiPF00864. P2X_receptor. 1 hit.
[Graphical view]
PIRSFiPIRSF005713. P2X_purinoceptor. 1 hit.
PRINTSiPR01311. P2X4RECEPTOR.
PR01307. P2XRECEPTOR.
TIGRFAMsiTIGR00863. P2X. 1 hit.
PROSITEiPS01212. P2X_RECEPTOR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9YI70-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAACCGAVRG FLFEYDTPRI VLIRSRKVGL INRAVQLAIL AYVIGWVFLW
60 70 80 90 100
EKGYQETDSV VSSVTTKVKG VTMTNTSTLG SRIWDVADYV IPPQEKNAVF
110 120 130 140 150
VMTNMIFTLN QSQSHCPELP DDNTECNNNS SCVPGYVSTH SNGIQTGACI
160 170 180 190 200
PYNSSIKTCE VFAWCPVEDD YHIPNPAFLQ GAENFTILVK NNIWYPKFNF
210 220 230 240 250
SKRNILPTFS SSYLKNCIYD AQTDPFCPIF RLGKIVEAAG QNFQEMAVEG
260 270 280 290 300
GVMGLQINWD CNLDRAASHC VPKYSFRRLD NKDSANTISP GYNFRFAKYY
310 320 330 340 350
KDSSGIETRT LIKAYGIRLD IIVFGKAGKF DVIPTMINIG SGLALFGVAT
360 370 380
VLCDIVVLYC MKKRYFYREK KYKYVEDYEL GTSET
Length:385
Mass (Da):43,330
Last modified:May 1, 1999 - v1
Checksum:i3DC500943B233EC5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF020315 mRNA. Translation: AAD01645.1.
AF218449 mRNA. Translation: AAG36785.1.
RefSeqiNP_989622.1. NM_204291.1.
UniGeneiGga.1369.

Genome annotation databases

GeneIDi374166.
KEGGigga:374166.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF020315 mRNA. Translation: AAD01645.1.
AF218449 mRNA. Translation: AAG36785.1.
RefSeqiNP_989622.1. NM_204291.1.
UniGeneiGga.1369.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000006190.

Proteomic databases

PaxDbiQ9YI70.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi374166.
KEGGigga:374166.

Organism-specific databases

CTDi5025.

Phylogenomic databases

eggNOGiENOG410IFJF. Eukaryota.
ENOG410XR0C. LUCA.
HOGENOMiHOG000232042.
HOVERGENiHBG053086.
KOiK05218.
PhylomeDBiQ9YI70.

Miscellaneous databases

NextBioi20813675.

Family and domain databases

Gene3Di2.60.490.10. 1 hit.
InterProiIPR003047. P2X4_purnocptor.
IPR027309. P2X_extracellular_dom.
IPR001429. P2X_purnocptor.
[Graphical view]
PANTHERiPTHR10125. PTHR10125. 1 hit.
PTHR10125:SF18. PTHR10125:SF18. 1 hit.
PfamiPF00864. P2X_receptor. 1 hit.
[Graphical view]
PIRSFiPIRSF005713. P2X_purinoceptor. 1 hit.
PRINTSiPR01311. P2X4RECEPTOR.
PR01307. P2XRECEPTOR.
TIGRFAMsiTIGR00863. P2X. 1 hit.
PROSITEiPS01212. P2X_RECEPTOR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Molecular Cloning and Expression of a P2X receptor from the Chick Embryo."
    Liu H., Hume R.I.
    Submitted (AUG-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: White leghornImported.
  2. "Characterization and expression of ATP P2X4 receptor from embryonic chick skeletal muscle."
    Bo X., Schoepfer R., Burnstock G.
    Drug Dev. Res. 53:22-28(2001)
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ9YI70_CHICK
AccessioniPrimary (citable) accession number: Q9YI70
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: November 11, 2015
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.