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Q9YI58

- Q9YI58_CHICK

UniProt

Q9YI58 - Q9YI58_CHICK

Protein
Submitted name:

Glutamate decarboxylase 67

Gene

GAD67

Organism
Gallus gallus (Chicken)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 86 (01 Oct 2014)
      Sequence version 1 (01 May 1999)
      Previous versions | rss
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    Functioni

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    GO - Molecular functioni

    1. carboxy-lyase activity Source: InterPro
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. carboxylic acid metabolic process Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotation

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Enzyme and pathway databases

    ReactomeiREACT_197535. GABA synthesis.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Glutamate decarboxylase 67Imported
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:GAD67Imported
    Synonyms:GAD1Imported
    OrganismiGallus gallus (Chicken)Imported
    Taxonomic identifieri9031 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus
    ProteomesiUP000000539: Chromosome 7

    Subcellular locationi

    GO - Cellular componenti

    1. intracellular Source: Ensembl

    Interactioni

    Protein-protein interaction databases

    STRINGi9031.ENSGALP00000015612.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9YI58.
    SMRiQ9YI58. Positions 89-589.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the group II decarboxylase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0076.
    GeneTreeiENSGT00730000110441.
    HOGENOMiHOG000005382.
    HOVERGENiHBG004980.
    InParanoidiQ9YI58.
    KOiK01580.
    OMAiEYLYTKI.
    OrthoDBiEOG7H1JM3.
    PhylomeDBiQ9YI58.
    TreeFamiTF314688.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProiIPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    IPR021115. Pyridoxal-P_BS.
    [Graphical view]
    PfamiPF00282. Pyridoxal_deC. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 1 hit.
    PROSITEiPS00392. DDC_GAD_HDC_YDC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9YI58-1 [UniParc]FASTAAdd to Basket

    « Hide

    MASSAPSSSN DAPDPAPTNL RPTTYDSWCG VAHGCTRKIG LKICGFLQRT    50
    NSLEDKGRIV GSLKERQSSK NLLACENSER EARFRRTETD FSNLYARDLL 100
    PAKNGEEQTM QFLLEVVDIL LNYVRKTFDR STKVLDFHHP HQLLEGMEGF 150
    NLELSDNPES LEQILVDCRD TLKYGVRTGH PRFFNQLSTG LDMIGLAGEW 200
    LTSTANTNMF TYEIAPVFVL MEQITLRKMR EIIGWSNKDG DGIFSPGGAI 250
    SNMYSIMAAR YKYFPEVKTK GMAAVPKLVL FTSEHSHYSI KKAGAALGFG 300
    TDNVILIKCN ERGKIIPADL EAKILEAKQK GYVPLFVNAT AGTTVYGAFD 350
    PIQEIADICE KYNLWLHVDA AWGGGLLMSR KHRHKLNGIE RANSVTWNPH 400
    KMMGVLLQCS AILVREKGIL QGCNQMCAGY LFQQDKQYDV SYDTGDKAIQ 450
    CGRHVDIFKF WLMWKAKGTV GFENQINKCL ELAEYLYTKI KNREEFEMVF 500
    EGEPEHTNVC FWYIPPSLRG MPDCDERREK LHRVAPKIKA LMMESGTTMV 550
    GYQPQGDKVN FFRMVISNPA ATKSDIDFLI EEIERLGQEL 590
    Length:590
    Mass (Da):66,711
    Last modified:May 1, 1999 - v1
    Checksum:i9DE9A26C834A5474
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AADN03005349 Genomic DNA. No translation available.
    AF030355 mRNA. Translation: AAD01902.1.
    RefSeqiNP_990244.1. NM_204913.1.
    UniGeneiGga.441.

    Genome annotation databases

    EnsembliENSGALT00000015628; ENSGALP00000015612; ENSGALG00000009589.
    ENSGALT00000043162; ENSGALP00000040750; ENSGALG00000009589.
    GeneIDi395743.
    KEGGigga:395743.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AADN03005349 Genomic DNA. No translation available.
    AF030355 mRNA. Translation: AAD01902.1 .
    RefSeqi NP_990244.1. NM_204913.1.
    UniGenei Gga.441.

    3D structure databases

    ProteinModelPortali Q9YI58.
    SMRi Q9YI58. Positions 89-589.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9031.ENSGALP00000015612.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSGALT00000015628 ; ENSGALP00000015612 ; ENSGALG00000009589 .
    ENSGALT00000043162 ; ENSGALP00000040750 ; ENSGALG00000009589 .
    GeneIDi 395743.
    KEGGi gga:395743.

    Organism-specific databases

    CTDi 2571.

    Phylogenomic databases

    eggNOGi COG0076.
    GeneTreei ENSGT00730000110441.
    HOGENOMi HOG000005382.
    HOVERGENi HBG004980.
    InParanoidi Q9YI58.
    KOi K01580.
    OMAi EYLYTKI.
    OrthoDBi EOG7H1JM3.
    PhylomeDBi Q9YI58.
    TreeFami TF314688.

    Enzyme and pathway databases

    Reactomei REACT_197535. GABA synthesis.

    Miscellaneous databases

    NextBioi 20815811.
    PROi Q9YI58.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProi IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    IPR021115. Pyridoxal-P_BS.
    [Graphical view ]
    Pfami PF00282. Pyridoxal_deC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 1 hit.
    PROSITEi PS00392. DDC_GAD_HDC_YDC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Characterization of glutamate decarboxylase in chicken."
      Wagberg F.
      Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: White leghornImported.
    2. "Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution."
      International Chicken Genome Sequencing Consortium
      Hillier L.W., Miller W., Birney E., Warren W., Hardison R.C., Ponting C.P., Bork P., Burt D.W., Groenen M.A.M., Delany M.E., Dodgson J.B., Chinwalla A.T., Cliften P.F., Clifton S.W., Delehaunty K.D., Fronick C., Fulton R.S., Graves T.A.
      , Kremitzki C., Layman D., Magrini V., McPherson J.D., Miner T.L., Minx P., Nash W.E., Nhan M.N., Nelson J.O., Oddy L.G., Pohl C.S., Randall-Maher J., Smith S.M., Wallis J.W., Yang S.-P., Romanov M.N., Rondelli C.M., Paton B., Smith J., Morrice D., Daniels L., Tempest H.G., Robertson L., Masabanda J.S., Griffin D.K., Vignal A., Fillon V., Jacobbson L., Kerje S., Andersson L., Crooijmans R.P., Aerts J., van der Poel J.J., Ellegren H., Caldwell R.B., Hubbard S.J., Grafham D.V., Kierzek A.M., McLaren S.R., Overton I.M., Arakawa H., Beattie K.J., Bezzubov Y., Boardman P.E., Bonfield J.K., Croning M.D.R., Davies R.M., Francis M.D., Humphray S.J., Scott C.E., Taylor R.G., Tickle C., Brown W.R.A., Rogers J., Buerstedde J.-M., Wilson S.A., Stubbs L., Ovcharenko I., Gordon L., Lucas S., Miller M.M., Inoko H., Shiina T., Kaufman J., Salomonsen J., Skjoedt K., Wong G.K.-S., Wang J., Liu B., Wang J., Yu J., Yang H., Nefedov M., Koriabine M., Dejong P.J., Goodstadt L., Webber C., Dickens N.J., Letunic I., Suyama M., Torrents D., von Mering C., Zdobnov E.M., Makova K., Nekrutenko A., Elnitski L., Eswara P., King D.C., Yang S.-P., Tyekucheva S., Radakrishnan A., Harris R.S., Chiaromonte F., Taylor J., He J., Rijnkels M., Griffiths-Jones S., Ureta-Vidal A., Hoffman M.M., Severin J., Searle S.M.J., Law A.S., Speed D., Waddington D., Cheng Z., Tuzun E., Eichler E., Bao Z., Flicek P., Shteynberg D.D., Brent M.R., Bye J.M., Huckle E.J., Chatterji S., Dewey C., Pachter L., Kouranov A., Mourelatos Z., Hatzigeorgiou A.G., Paterson A.H., Ivarie R., Brandstrom M., Axelsson E., Backstrom N., Berlin S., Webster M.T., Pourquie O., Reymond A., Ucla C., Antonarakis S.E., Long M., Emerson J.J., Betran E., Dupanloup I., Kaessmann H., Hinrichs A.S., Bejerano G., Furey T.S., Harte R.A., Raney B., Siepel A., Kent W.J., Haussler D., Eyras E., Castelo R., Abril J.F., Castellano S., Camara F., Parra G., Guigo R., Bourque G., Tesler G., Pevzner P.A., Smit A., Fulton L.A., Mardis E.R., Wilson R.K.
      Nature 432:695-716(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Red jungle fowlImported.
    3. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: Red jungle fowlImported.
    4. Ensembl
      Submitted (MAY-2013) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: Red jungle fowlImported.

    Entry informationi

    Entry nameiQ9YI58_CHICK
    AccessioniPrimary (citable) accession number: Q9YI58
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 1, 1999
    Last sequence update: May 1, 1999
    Last modified: October 1, 2014
    This is version 86 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3