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Protein
Submitted name:

Tight junction protein

Gene

ZO-2

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Tight junction proteinImported
Gene namesi
Name:ZO-2Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Proteomic databases

PaxDbiQ9YHV2.

Structurei

3D structure databases

ProteinModelPortaliQ9YHV2.
SMRiQ9YHV2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 97PDZ (DHR)InterPro annotationAdd BLAST88
Domaini274 – 352PDZ (DHR)InterPro annotationAdd BLAST79
Domaini478 – 559PDZ (DHR)InterPro annotationAdd BLAST82
Domaini573 – 638SH3InterPro annotationAdd BLAST66
Domaini743 – 845Guanylate kinase-likeInterPro annotationAdd BLAST103

Keywords - Domaini

SH3 domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3580. Eukaryota.
ENOG410XQP3. LUCA.
HOGENOMiHOG000230923.
HOVERGENiHBG017627.
KOiK06098.
PhylomeDBiQ9YHV2.

Family and domain databases

CDDicd12027. SH3_ZO-2. 1 hit.
InterProiView protein in InterPro
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR027417. P-loop_NTPase.
IPR001478. PDZ.
IPR011511. SH3_2.
IPR001452. SH3_domain.
IPR005417. ZO.
IPR005419. ZO-2.
IPR035598. ZO-2_SH3.
PfamiView protein in Pfam
PF00625. Guanylate_kin. 1 hit.
PF00595. PDZ. 3 hits.
PF07653. SH3_2. 1 hit.
PRINTSiPR01597. ZONOCCLUDNS.
PR01599. ZONOCCLUDNS2.
SMARTiView protein in SMART
SM00072. GuKc. 1 hit.
SM00228. PDZ. 3 hits.
SUPFAMiSSF50044. SSF50044. 1 hit.
SSF50156. SSF50156. 3 hits.
SSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS50052. GUANYLATE_KINASE_2. 1 hit.
PS50106. PDZ. 3 hits.
PS50002. SH3. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9YHV2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEELIWEQYT VTLQKDSKRG FGIAVSGGRD NPHFENGETS IVISDVLPGG
60 70 80 90 100
PADGLLQEND RVVIVNGTPM ENVPHSFAVQ QLRKSGKVAT IVVKRPRKVQ
110 120 130 140 150
AAALRKNPSL DYEDRALEVM DDHAEFDGKS ARSGYSERSW RSGNGGRSQS
160 170 180 190 200
WGNSLDQSYR DDQDREHNRS RGRSRGCSYS RDQSRGRSID RSLDQDYGRD
210 220 230 240 250
RSRGRSVDRD GGYGQDYRRD YSPASYRHGS QPDPRYVREV RSLSRDRLHS
260 270 280 290 300
RSPSPETRHQ HEYLGPQDQN GPISVLLTKG KHNEEYGLRL GSQIFIKEMT
310 320 330 340 350
STGLATKDGN LHEGDIILKI NGTVTENMSL ADARKLIEKS RGKLQLVVLR
360 370 380 390 400
DRKQTLLNIP SLNDSDSEMD DISEIESNRS FSPQDDRLHH SDLDLHSSNE
410 420 430 440 450
KLKEKTNAKD DPSNRMSRMG AMPTPFKSTG DIATTAVTVV DANKEPKYQD
460 470 480 490 500
DVAVPQPKAV TRTILKPSPE DEAIYGPNTK MVRFKKGDSV GLRLAGGNDV
510 520 530 540 550
GIFIAGIQEG TSADQEGLQE GDQILKVNAQ DFRGIVREDA VLYLLEIPKG
560 570 580 590 600
DTVTILAQSK YEVYRDIMAC GRGDSFFIRS HFECEKESPQ SLAFTRGEIF
610 620 630 640 650
RVVDTLYDGK LGNWLAVRIG NELEKGLIPN RSRAEQMASV QNAQKDGPSD
660 670 680 690 700
RADFWRTRGQ RSGVKKNLRK SREDLTAIVS VGTKFPAYER VQLREAGFKR
710 720 730 740 750
PVVIFGPIAD VAMEKLSTDL PHLYQTAKTE PRDAGSEKAT GVVRLNTVRQ
760 770 780 790 800
IIEQDKHALL DVTPKAVDLL NYTQWFPIVV FFNPDSKQGV KTMRQRLCST
810 820 830 840 850
SNKSSRKLYE QANKLKKTCS HLFTATINLN SANDSWYGSL KDTIQQQQGE
860 870 880 890 900
AVWVSEGKVD GMEDDADDRM SYLTAMGADY LSCDSRLISD LEDTDGEGGA
910 920 930 940 950
YTDNELDEPL DEPRISSVGR SSEPVHHEEN IKKFSLEQRT PLRKAGSREI
960 970 980 990 1000
LREPSPPPAF KPEPPKGKLQ NKEDLYDFPK NYDSKPSSIH VSSETSTVSA
1010 1020 1030 1040 1050
KAAPPPVSVK PTFGRPILRN TQPAVPSAEE EEEGKLEEEG SEQENTPKSV
1060 1070 1080 1090 1100
LRKVKIFEEM DHKARLQRMQ ELQEAQNARI EIAQKHPDIY AVPVKTQKSD
1110 1120 1130 1140 1150
QNWPQPISCR PPEPQKPPTR PYLEDRGSCG SDGEEEEEYR RQLSDHSKKG
1160
YYGQPPRYRD TEL
Length:1,163
Mass (Da):130,669
Last modified:May 1, 1999 - v1
Checksum:i3639431A560B1D4E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF085184 mRNA. Translation: AAC95469.1.
PIRiJE0366.
RefSeqiNP_990249.1. NM_204918.1.
UniGeneiGga.50260.

Genome annotation databases

GeneIDi395751.
KEGGigga:395751.

Similar proteinsi

Entry informationi

Entry nameiQ9YHV2_CHICK
AccessioniPrimary (citable) accession number: Q9YHV2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: August 30, 2017
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)