Q9YH61 (Q9YH61_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Glycogen synthase kinase 3 alpha EMBL CAA11419.1 Ensembl ENSDARP00000011670 Ensembl ENSDARP00000099545

Gene names

Name:	gsk3a ZFIN ZDB-GENE-990714-3 Ensembl ENSDARP00000011670 EMBL AAH56332.1 Ensembl ENSDARP00000099545
Synonyms:	GSK3 EMBL CAA11419.1

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) EMBL CAA11419.1

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length	440 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU000304 Nucleotide-binding
Molecular function	Kinase EMBL CAA11419.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cardiac muscle cell development Inferred from mutant phenotype. Source: ZFIN dorsal/ventral pattern formation Inferred from genetic interaction. Source: ZFIN heart looping Inferred from mutant phenotype. Source: ZFIN
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9YH61 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: 66A8E8D070ACA093	FASTA	440	48,065
	10 20 30 40 50 60 MSGSGRPRTS SFAEPPGVPG AAAAAAGSAV AGGSSSGKTG GAQASGGSSS GFGNLKLGRD 70 80 90 100 110 120 SGKVTTVVAT PGQGPDRPQE VSYTDIKVIG NGSFGVVYQA RLIDSQEMVA IKKVLQDKRF 130 140 150 160 170 180 KNRELQIMRK LDHCNIVRLR YFFYSSGEKK DEVYLNLVLD FVPETVYRVA RHFNKSKTTI 190 200 210 220 230 240 PIIYVKVYMY QLFRSLAYIH SQGVCHRDIK PQNLLVDPDT AVLKLCDFGS AKQLVRGEPN 250 260 270 280 290 300 VSYICSRYYR APELIFGATD YTSNIDIWSA GCVLAELLLG QPIFPGDSGV DQLVEIIKVL 310 320 330 340 350 360 GTPTREQIRE MNPNYTEFKF PQIKAHPWTK VFKPRTPPEA ISLCSRLLEY TPVTRLSPLE 370 380 390 400 410 420 ACAHAFFDEL RQPNARLPNG RELPQLFNFS PVELSIQPQL NSILIPPHAR SQTTPASHEG 430 440 SGSDGPAQSS SAPGPLSNNT

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Differential expression of glycogen synthase kinase 3 genes during zebrafish embryogenesis." Tsai J.N., Lee C.H., Jeng H., Chi W.K., Chang W.C. Mech. Dev. 91:387-391(2000) [PubMed: 10704871] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	NIH - Zebrafish Gene Collection (ZGC) project Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Embryo EMBL AAH56332.1.
[3]	NIH - Zebrafish Gene Collection (ZGC) project Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Embryo EMBL AAH65952.1.
[4]	"The genomic sequence of Danio rerio." The Danio rerio Sequencing Project at the Sanger Institute Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tuebingen Ensembl ENSDARP00000011670 Ensembl ENSDARP00000099545.
[5]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Tuebingen Ensembl ENSDARP00000011670 Ensembl ENSDARP00000099545.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR848744 Genomic DNA. No translation available. BC056332 mRNA. Translation: AAH56332.1. BC065952 mRNA. Translation: AAH65952.1. AJ223501 mRNA. Translation: CAA11419.1.
IPI	IPI00507619.
RefSeq	NP_571465.1. NM_131390.2.
UniGene	Dr.75529.
3D structure databases
HSSP	HSSP built from PDB template 1Q3W based on UniProtKB P49841.
ProteinModelPortal	Q9YH61.
SMR	Q9YH61. Positions 63-410.
ModBase	Search...
Proteomic databases
PRIDE	Q9YH61.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSDART00000024935; ENSDARP00000011670; ENSDARG00000015681. ENSDART00000111481; ENSDARP00000099545; ENSDARG00000015681.
GeneID	30664.
KEGG	dre:30664.
Organism-specific databases
CTD	2931.
ZFIN	ZDB-GENE-990714-3. gsk3a.
Phylogenomic databases
GeneTree	ENSGT00520000055635.
HOGENOM	HBG755340.
HOVERGEN	HBG014652.
InParanoid	Q9YH61.
OMA	FGNLKLP.
OrthoDB	EOG4WH8KZ.
PhylomeDB	Q9YH61.
Gene expression databases
ArrayExpress	Q9YH61.
Bgee	Q9YH61.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR017442. Se/Thr_kinase-like_dom. IPR008271. Ser/Thr_kinase_AS. IPR002290. Ser/Thr_kinase_dom. [Graphical view]
KO	K08822.
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
SMART	SM00220. S_TKc. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9YH61_DANRE

Accession

Primary (citable) accession number: Q9YH61

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 1999
Last sequence update:	May 1, 1999
Last modified:	January 25, 2012
This is version 90 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)