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Q9YGW6

- Q9YGW6_CHICK

UniProt

Q9YGW6 - Q9YGW6_CHICK

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Protein
Submitted name:

Ezrin

Gene
EZR
Organism
Gallus gallus (Chicken)
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. actin filament binding Source: UniProtKB
  2. cell adhesion molecule binding Source: BHF-UCL

GO - Biological processi

  1. actin filament bundle assembly Source: UniProtKB
  2. establishment or maintenance of apical/basal cell polarity Source: Ensembl
  3. leukocyte cell-cell adhesion Source: Ensembl
  4. membrane to membrane docking Source: Ensembl
  5. receptor internalization Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
EzrinImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:EZRImported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus
ProteomesiUP000000539: Chromosome 3

Subcellular locationi

GO - Cellular componenti

  1. actin cytoskeleton Source: UniProtKB
  2. actin filament Source: UniProtKB
  3. apical plasma membrane Source: Ensembl
  4. cytosol Source: Ensembl
  5. extrinsic component of membrane Source: UniProtKB
  6. filopodium Source: Ensembl
  7. focal adhesion Source: Ensembl
  8. microvillus Source: Ensembl
  9. nucleolus Source: Ensembl
  10. ruffle Source: Ensembl
  11. uropod Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ9YGW6.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000022293.

Structurei

3D structure databases

ProteinModelPortaliQ9YGW6.
SMRiQ9YGW6. Positions 1-325, 499-585.

Family & Domainsi

Sequence similaritiesi

Contains FERM domain.SAAS annotations

Phylogenomic databases

eggNOGiNOG236035.
GeneTreeiENSGT00650000092953.
HOGENOMiHOG000007113.
HOVERGENiHBG002185.
InParanoidiQ9YGW6.
KOiK08007.
OrthoDBiEOG7BGHK6.
PhylomeDBiQ9YGW6.
TreeFamiTF313935.

Family and domain databases

Gene3Di1.20.80.10. 1 hit.
2.30.29.30. 1 hit.
InterProiIPR019749. Band_41_domain.
IPR019750. Band_41_fam.
IPR011174. ERM.
IPR011259. ERM_C_dom.
IPR000798. Ez/rad/moesin_like.
IPR014352. FERM/acyl-CoA-bd_prot_3-hlx.
IPR019748. FERM_central.
IPR019747. FERM_CS.
IPR000299. FERM_domain.
IPR018979. FERM_N.
IPR018980. FERM_PH-like_C.
IPR008954. Moesin_tail.
IPR011993. PH_like_dom.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PfamiPF00769. ERM. 1 hit.
PF09380. FERM_C. 1 hit.
PF00373. FERM_M. 1 hit.
PF09379. FERM_N. 1 hit.
[Graphical view]
PIRSFiPIRSF002305. ERM. 1 hit.
PRINTSiPR00935. BAND41.
PR00661. ERMFAMILY.
SMARTiSM00295. B41. 1 hit.
[Graphical view]
SUPFAMiSSF47031. SSF47031. 1 hit.
SSF48678. SSF48678. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiPS00660. FERM_1. 1 hit.
PS00661. FERM_2. 1 hit.
PS50057. FERM_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9YGW6-1 [UniParc]FASTAAdd to Basket

« Hide

MPKPINVRVV TVDAELEFAI QPNTTGKQLF DQVVKTIGLR EVWYFGLQYV    50
DNKGFQTWLK LDKKVSAQEI RKENPLQFRF RAKFFPEDVA EELIQDITQK 100
LFFLQVKEGI LSDEIYCPPE TAVLLGSYAV QAKFGDYNKD VHKPGYLNSE 150
RLIPQRVMDQ HKLSRDQWEE RIQVWHAEHS GMLKENAMLE YLKIAQDLEM 200
YGINYFEIKN KKGTDLWLGV DALGLNIYEK DDKLTPKIGF PWSEIRNISF 250
NDKKFVIKPI DKKAPDFVFY APRLRINKRI LQLCMGNHEL YMRRRKPDTI 300
EVQQMKAQAR EEKHQKQLER QQLENEKKKR ETIEREKEQM LREKEELLVR 350
LQEYEVKTKR AEKELSDQIQ RALQLEEERR RAQEEAERLE ADRLAALQAK 400
EELERQNIDQ IKSQEQLAAE LAEYTAKIAL LEEARKRKES EVEEWQIRAR 450
EAQEDLVKTK EELHLVMTAP PPPPPIYEPV NYHVHDNLHD EGSEYSAYSA 500
EFSSEGIRND RNEEKRITEA EKNERVQRQL KALTDELAQA RDEDKRTQND 550
IIHSENVRQG RDKYKTLRQI RQGNTKQRID EFEAM 585
Length:585
Mass (Da):69,367
Last modified:May 1, 1999 - v1
Checksum:i854C6348F783CAEC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AADN03003294 Genomic DNA. No translation available.
AB019790 mRNA. Translation: BAA75497.1.
RefSeqiNP_990216.1. NM_204885.1.
UniGeneiGga.40252.

Genome annotation databases

EnsembliENSGALT00000022333; ENSGALP00000022293; ENSGALG00000013742.
GeneIDi395701.
KEGGigga:395701.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AADN03003294 Genomic DNA. No translation available.
AB019790 mRNA. Translation: BAA75497.1 .
RefSeqi NP_990216.1. NM_204885.1.
UniGenei Gga.40252.

3D structure databases

ProteinModelPortali Q9YGW6.
SMRi Q9YGW6. Positions 1-325, 499-585.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9031.ENSGALP00000022293.

Proteomic databases

PaxDbi Q9YGW6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSGALT00000022333 ; ENSGALP00000022293 ; ENSGALG00000013742 .
GeneIDi 395701.
KEGGi gga:395701.

Organism-specific databases

CTDi 7430.

Phylogenomic databases

eggNOGi NOG236035.
GeneTreei ENSGT00650000092953.
HOGENOMi HOG000007113.
HOVERGENi HBG002185.
InParanoidi Q9YGW6.
KOi K08007.
OrthoDBi EOG7BGHK6.
PhylomeDBi Q9YGW6.
TreeFami TF313935.

Miscellaneous databases

NextBioi 20815771.

Family and domain databases

Gene3Di 1.20.80.10. 1 hit.
2.30.29.30. 1 hit.
InterProi IPR019749. Band_41_domain.
IPR019750. Band_41_fam.
IPR011174. ERM.
IPR011259. ERM_C_dom.
IPR000798. Ez/rad/moesin_like.
IPR014352. FERM/acyl-CoA-bd_prot_3-hlx.
IPR019748. FERM_central.
IPR019747. FERM_CS.
IPR000299. FERM_domain.
IPR018979. FERM_N.
IPR018980. FERM_PH-like_C.
IPR008954. Moesin_tail.
IPR011993. PH_like_dom.
IPR029071. Ubiquitin-rel_dom.
[Graphical view ]
Pfami PF00769. ERM. 1 hit.
PF09380. FERM_C. 1 hit.
PF00373. FERM_M. 1 hit.
PF09379. FERM_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF002305. ERM. 1 hit.
PRINTSi PR00935. BAND41.
PR00661. ERMFAMILY.
SMARTi SM00295. B41. 1 hit.
[Graphical view ]
SUPFAMi SSF47031. SSF47031. 1 hit.
SSF48678. SSF48678. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEi PS00660. FERM_1. 1 hit.
PS00661. FERM_2. 1 hit.
PS50057. FERM_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Specific expression of ezrin, a cytoskeletal-membrane linker protein, in a subset of chick retinotectal and sensory projections."
    Takahashi M., Yamagata M., Noda M.
    Eur. J. Neurosci. 11:545-558(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: White LeghornImported.
    Tissue: BrainImported.
  2. "Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution."
    International Chicken Genome Sequencing Consortium
    Hillier L.W., Miller W., Birney E., Warren W., Hardison R.C., Ponting C.P., Bork P., Burt D.W., Groenen M.A.M., Delany M.E., Dodgson J.B., Chinwalla A.T., Cliften P.F., Clifton S.W., Delehaunty K.D., Fronick C., Fulton R.S., Graves T.A.
    , Kremitzki C., Layman D., Magrini V., McPherson J.D., Miner T.L., Minx P., Nash W.E., Nhan M.N., Nelson J.O., Oddy L.G., Pohl C.S., Randall-Maher J., Smith S.M., Wallis J.W., Yang S.-P., Romanov M.N., Rondelli C.M., Paton B., Smith J., Morrice D., Daniels L., Tempest H.G., Robertson L., Masabanda J.S., Griffin D.K., Vignal A., Fillon V., Jacobbson L., Kerje S., Andersson L., Crooijmans R.P., Aerts J., van der Poel J.J., Ellegren H., Caldwell R.B., Hubbard S.J., Grafham D.V., Kierzek A.M., McLaren S.R., Overton I.M., Arakawa H., Beattie K.J., Bezzubov Y., Boardman P.E., Bonfield J.K., Croning M.D.R., Davies R.M., Francis M.D., Humphray S.J., Scott C.E., Taylor R.G., Tickle C., Brown W.R.A., Rogers J., Buerstedde J.-M., Wilson S.A., Stubbs L., Ovcharenko I., Gordon L., Lucas S., Miller M.M., Inoko H., Shiina T., Kaufman J., Salomonsen J., Skjoedt K., Wong G.K.-S., Wang J., Liu B., Wang J., Yu J., Yang H., Nefedov M., Koriabine M., Dejong P.J., Goodstadt L., Webber C., Dickens N.J., Letunic I., Suyama M., Torrents D., von Mering C., Zdobnov E.M., Makova K., Nekrutenko A., Elnitski L., Eswara P., King D.C., Yang S.-P., Tyekucheva S., Radakrishnan A., Harris R.S., Chiaromonte F., Taylor J., He J., Rijnkels M., Griffiths-Jones S., Ureta-Vidal A., Hoffman M.M., Severin J., Searle S.M.J., Law A.S., Speed D., Waddington D., Cheng Z., Tuzun E., Eichler E., Bao Z., Flicek P., Shteynberg D.D., Brent M.R., Bye J.M., Huckle E.J., Chatterji S., Dewey C., Pachter L., Kouranov A., Mourelatos Z., Hatzigeorgiou A.G., Paterson A.H., Ivarie R., Brandstrom M., Axelsson E., Backstrom N., Berlin S., Webster M.T., Pourquie O., Reymond A., Ucla C., Antonarakis S.E., Long M., Emerson J.J., Betran E., Dupanloup I., Kaessmann H., Hinrichs A.S., Bejerano G., Furey T.S., Harte R.A., Raney B., Siepel A., Kent W.J., Haussler D., Eyras E., Castelo R., Abril J.F., Castellano S., Camara F., Parra G., Guigo R., Bourque G., Tesler G., Pevzner P.A., Smit A., Fulton L.A., Mardis E.R., Wilson R.K.
    Nature 432:695-716(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Red jungle fowlImported.
  3. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Red jungle fowlImported.

Entry informationi

Entry nameiQ9YGW6_CHICK
AccessioniPrimary (citable) accession number: Q9YGW6
Secondary accession number(s): F1P3H9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: July 9, 2014
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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