Q9YGT5 (HXA9B_DANRE) Reviewed, UniProtKB/Swiss-Prot
Last modified
December 14, 2011.
Version 79.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Homeobox protein Hox-A9b | ||||
| Gene names |
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| Organism | Danio rerio (Zebrafish) (Brachydanio rerio) | ||||
| Taxonomic identifier | 7955 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio |
Protein attributes
| Sequence length | 253 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level |
General annotation (Comments)
| Function | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis By similarity. |
| Subcellular location | Nucleus By similarity. |
| Sequence similarities | Belongs to the Abd-B homeobox family. Contains 1 homeobox DNA-binding domain. |
| Sequence caution | The sequence AAD15942.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence CAD59109.1 differs from that shown. Reason: Erroneous gene model prediction. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Transcription Transcription regulation |
| Cellular component | Nucleus |
| Domain | Homeobox |
| Ligand | DNA-binding |
| Molecular function | Developmental protein |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | multicellular organismal development Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependentInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding transcription factor activityInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Zebrafish hox clusters and vertebrate genome evolution." Amores A., Force A., Yan Y.-L., Joly L., Amemiya C., Fritz A., Ho R.K., Langeland J., Prince V.E., Wang Y.-L., Westerfield M., Ekker M., Postlethwait J.H. Science 282:1711-1714(1998) [PubMed: 9831563] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
| [2] | The Danio rerio sequencing project at the Sanger Institute Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AB. |
| [3] | NIH - Zebrafish Gene Collection (ZGC) project Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Embryo. |
| [4] | "Genomic annotation and transcriptome analysis of the zebrafish (Danio rerio) hox complex with description of a novel member, hoxb13a." Corredor-Adamez M., Welten M.C.M., Spaink H.P., Jeffery J.E., Schoon R.T., de Bakker M.A.G., Bagowski C.P., Meijer A.H., Verbeek F.J., Richardson M.K. Evol. Dev. 7:362-375(2005) [PubMed: 16174031] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 87-181. Strain: Tuebingen. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AF071249 Genomic DNA. Translation: AAD15942.1. Sequence problems. AL645795 Genomic DNA. Translation: CAD59109.1. Sequence problems. BC095300 mRNA. Translation: AAH95300.1. DQ060537 mRNA. Translation: AAY67915.1. |
| IPI | IPI00498950. |
| RefSeq | NP_571608.1. NM_131533.1. |
| UniGene | Dr.88308. |
3D structure databases | |
| ProteinModelPortal | Q9YGT5. |
| SMR | Q9YGT5. Positions 175-251. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q9YGT5. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 58048. |
| KEGG | dre:58048. |
Organism-specific databases | |
| CTD | 58048. |
| ZFIN | ZDB-GENE-000823-2. hoxa9b. |
Phylogenomic databases | |
| eggNOG | fiNOG15599. |
| GeneTree | ENSGT00560000076560. |
| HOGENOM | HBG714137. |
| HOVERGEN | HBG016849. |
| OrthoDB | EOG4D26QZ. |
Gene expression databases | |
| Bgee | Q9YGT5. |
Family and domain databases | |
| InterPro | IPR001356. Homeobox. IPR017970. Homeobox_CS. IPR020479. Homeobox_eu. IPR017112. Homeobox_Hox9. IPR009057. Homeodomain-like. IPR012287. Homeodomain-rel. IPR006711. Hox9_activation_N. [Graphical view] |
| Gene3D | G3DSA:1.10.10.60. Homeodomain-rel. 1 hit. |
| Pfam | PF00046. Homeobox. 1 hit. PF04617. Hox9_act. 1 hit. [Graphical view] |
| PIRSF | PIRSF037109. Homeobox_Hox9. 1 hit. |
| PRINTS | PR00024. HOMEOBOX. |
| SMART | SM00389. HOX. 1 hit. [Graphical view] |
| SUPFAM | SSF46689. Homeodomain_like. 1 hit. |
| PROSITE | PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | HXA9B_DANRE | ||||||||
| Accession | Primary (citable) accession number: Q9YGT5 Secondary accession number(s): Q4PRA6, Q503J9, Q8AWY3 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Chordata Protein Annotation Program | ||||||||
Relevant documents
| Vertebrate homeotic Hox proteins Nomenclature of vertebrate homeotic Hox proteins and list of entries |
| SIMILARITY comments Index of protein domains and families |

Clusters with