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Q9YGB1 (TRPF_THEKO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
N-(5'-phosphoribosyl)anthranilate isomerase

Short name=PRAI
EC=5.3.1.24
Gene names
Name:trpF
Ordered Locus Names:TK0256
OrganismThermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) [Reference proteome] [HAMAP]
Taxonomic identifier69014 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaeThermococcus

Protein attributes

Sequence length208 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP-Rule MF_00135

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP-Rule MF_00135

Sequence similarities

Belongs to the TrpF family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 208208N-(5'-phosphoribosyl)anthranilate isomerase HAMAP-Rule MF_00135
PRO_0000154413

Sequences

Sequence LengthMass (Da)Tools
Q9YGB1 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: 54D5DDB85F9312A8

FASTA20823,049
        10         20         30         40         50         60 
MVEFVKICGV KTMDELRLVE RYADATGVVV NSRSKRKVPL KTAAELIEMA EIPIYLVSTM 

        70         80         90        100        110        120 
KTFPEWANAV EKTGAEYIQV HSDMHPKAVN RLKDEYGVSV MKAFMVPRES DDPAEDAERL 

       130        140        150        160        170        180 
LELIGQYEVD KILLDTGVGS GRRHDYRVSA IIAKEYPIVL AGGLTPENVG EAIRWVKPAG 

       190        200 
VDVSSGVERN GVKDRVLIEA FMAVVRNG 

« Hide

References

« Hide 'large scale' references
[1]"The tryptophan biosynthesis gene cluster trpCDEGFBA from Pyrococcus kodakaraensis KOD1 is regulated at the transcriptional level and expressed as a single mRNA."
Tang X., Ezaki S., Fujiwara S., Takagi M., Atomi H., Imanaka T.
Mol. Gen. Genet. 262:815-821(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC BAA-918 / JCM 12380 / KOD1.
[2]"Complete genome sequence of the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1 and comparison with Pyrococcus genomes."
Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.
Genome Res. 15:352-363(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-918 / JCM 12380 / KOD1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB030011 Genomic DNA. Translation: BAA82549.1.
AP006878 Genomic DNA. Translation: BAD84445.1.
PIRT43926.
RefSeqYP_182669.1. NC_006624.1.

3D structure databases

ProteinModelPortalQ9YGB1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING69014.TK0256.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAD84445; BAD84445; TK0256.
GeneID3235375.
KEGGtko:TK0256.

Phylogenomic databases

eggNOGCOG0135.
HOGENOMHOG000161598.
KOK01817.

Enzyme and pathway databases

BioCycTKOD69014:GH72-258-MONOMER.
UniPathwayUPA00035; UER00042.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_00135. PRAI.
InterProIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTRPF_THEKO
AccessionPrimary (citable) accession number: Q9YGB1
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1999
Last modified: May 14, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways