Q9YGA7 (Q9YGA7_THELI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphorylase RuleBase RU000587
EC=2.4.1.1 RuleBase RU000587

Gene names

Name:

malP EMBL AAD28735.1

Organism

Thermococcus litoralis EMBL AAD28735.1

Taxonomic identifier

2265 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Thermococcus

Protein attributes

Sequence length	831 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties By similarity. RuleBase RU000587
Catalytic activity	(1,4-alpha-D-glucosyl)(n) + phosphate = (1,4-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate. RuleBase RU000587
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000587
Sequence similarities	Belongs to the glycogen phosphorylase family. RuleBase RU004179

Ontologies

Keywords
Biological process	Carbohydrate metabolism RuleBase RU000587
Molecular function	Glycosyltransferase RuleBase RU000587 Transferase
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	phosphorylase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9YGA7 [UniParc]. Last modified November 1, 1999. Version 1. Checksum: 80FBC5306BBA52ED	FASTA	831	96,683
	10 20 30 40 50 60 METVVNQIKS KLPENLEGLL DLAYNYWWSW NRRATKLWEK IDPEHWWEYK NPVKLLLDTP 70 80 90 100 110 120 EERLKELSKD DDFINLYELV IDQFRHYMNP ESTWFSTNYP KWEEPVIYLC MEYGISKSLP 130 140 150 160 170 180 IYSGGLGILA GDHIKTASDL GIPLIAIGLL YKHGYFKQEI DKDGKQIEVF PEYNPEEMPI 190 200 210 220 230 240 KPLTTEKGKP LLIEVPIEDR IVYARAFEVN VGRVKLYLLD TDVPQNSPDD RTICDYLYNA 250 260 270 280 290 300 EIDKRIKQEI LLGIGGMRLL RMLGIDPAVI HLNEGHPAFA NFQRIAWYME EGLNFLEALT 310 320 330 340 350 360 VVRGTTIFTT HTPVPAGHDK FPIAEVEKRL AKFLEGLPKD EFLNLGREGD QFNMTLLSIR 370 380 390 400 410 420 TSSYVNAVSK LHSKVTKEMW RHLWNGVPLD EIPVEGITNG VHTKTWLHNE IKKLVDRYIG 430 440 450 460 470 480 RVWRDYAELE GLWYGVERIP DEELWEAHLK AKREFIELIK RKIKERNERL GIEEPLPEID 490 500 510 520 530 540 ENALIIGFAR RFATYKRATL ILTDLERLKK IVNNPERPVY IIFGGKAHPR DEAGKEFLRK 550 560 570 580 590 600 VYEVSQMPEF KNKIMVFENY DMGSARAMVA GVDVWLNNPR RPLEASGTSG MKAGLNGVLN 610 620 630 640 650 660 LSVYDGWWVE GYNGKNGWVI GDESLEPETE KDNIRDAQSL YNLLENEVIP TYYENRARWI 670 680 690 700 710 720 YMMKESIKSI APRFSTHRMV KEYVDKFYSK ALANAILLQR DSFKATREIA SWKAKIFNSW 730 740 750 760 770 780 DKVEIERIIT HDATGVEVIV NLDGLSPEDV KVEIYYGVKA EGYAIEKPYV IELKHPQSLG 790 800 810 820 830 GNRWLYRYEG NALKNLGHPC WHYAVRVYPY HDKLPHKFLL GLIKWKGFFE L

References

[1]	"Maltose metabolism in the hyperthermophilic archaeon Thermococcus litoralis: purification and characterization of key enzymes." Xavier K.B., Peist R., Kossmann M., Boos W., Santos H. J. Bacteriol. 181:3358-3367(1999) [PubMed: 10348846] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF115479 Genomic DNA. Translation: AAD28735.1.
3D structure databases
ProteinModelPortal	Q9YGA7.
ModBase	Search...
Protein family/group databases
CAZy	GT35. Glycosyltransferase Family 35.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR011834. Agluc_phsphrylas. IPR000811. Glyco_trans_35. IPR024517. Glycogen_phosphorylase_DUF3417. [Graphical view]
PANTHER	PTHR11468. Glyco_trans_35. 1 hit.
Pfam	PF11897. DUF3417. 1 hit. PF00343. Phosphorylase. 1 hit. [Graphical view]
PIRSF	PIRSF000460. Pprylas_GlgP. 1 hit.
TIGRFAMs	TIGR02094. More_P_ylases. 1 hit.
PROSITE	PS00102. PHOSPHORYLASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9YGA7_THELI

Accession

Primary (citable) accession number: Q9YGA7

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1999
Last sequence update:	November 1, 1999
Last modified:	October 19, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)