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Q9YG90

- ALF1_AERPE

UniProt

Q9YG90 - ALF1_AERPE

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Protein

Probable fructose-bisphosphate aldolase class 1

Gene

fba

Organism
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.

Enzyme regulationi

Activated by citrate.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei184 – 1841Schiff-base intermediate with dihydroxyacetone-PBy similarity

GO - Molecular functioni

  1. fructose-bisphosphate aldolase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

Schiff base

Enzyme and pathway databases

BioCyciAPER272557:GJD6-8-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable fructose-bisphosphate aldolase class 1 (EC:4.1.2.13)
Alternative name(s):
Probable fructose-bisphosphate aldolase class I
Short name:
FBP aldolase
Gene namesi
Name:fba
Ordered Locus Names:APE_0011.1
OrganismiAeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Taxonomic identifieri272557 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiDesulfurococcalesDesulfurococcaceaeAeropyrum
ProteomesiUP000002518: Chromosome

Subcellular locationi

Cytoplasm Curated

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 272272Probable fructose-bisphosphate aldolase class 1PRO_0000138947Add
BLAST

Interactioni

Subunit structurei

Homooligomer.By similarity

Protein-protein interaction databases

STRINGi272557.APE_0011.1.

Structurei

3D structure databases

ProteinModelPortaliQ9YG90.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the DeoC/FbaB aldolase family.Curated

Phylogenomic databases

eggNOGiCOG1830.
HOGENOMiHOG000224790.
KOiK11645.
OMAiSRNMVII.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR002915. DeoC/FbaB/lacD_aldolase.
[Graphical view]
PfamiPF01791. DeoC. 1 hit.
[Graphical view]
PIRSFiPIRSF038992. Aldolase_Ia. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9YG90 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MISSQDVGKR VRLSRILPDG RSVIFAFDHG IEHGPGEIPE ERLDPRLLIR
60 70 80 90 100
EVVEAGVDAI MTTPGIARLT WDIWANRVAM IIKVSGKTSI RPQDDQFLQS
110 120 130 140 150
AISSVDEVVA LGGDGVAATV YWGSQFEDKM LERWTRIRLR AEKLGLPALQ
160 170 180 190 200
LAYPRGPHIK NRYAVDIVAY GARAAMETGA DLIKTYYTGS TESFRRVVSA
210 220 230 240 250
AGGVPVLMSG GARTPSPQEF LHKVYSVMEA GGGGVVVGRN IFQAGDIRAM
260 270
VKAIRAIVHE GFDPEKASKL LG
Length:272
Mass (Da):29,583
Last modified:June 6, 2002 - v3
Checksum:iD992DAFA81A6ADAF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000002 Genomic DNA. Translation: BAA78920.2.
PIRiF72752.
RefSeqiNP_146901.2. NC_000854.2.
WP_010865431.1. NC_000854.2.

Genome annotation databases

EnsemblBacteriaiBAA78920; BAA78920; APE_0011.1.
GeneIDi1445583.
KEGGiape:APE_0011.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000002 Genomic DNA. Translation: BAA78920.2 .
PIRi F72752.
RefSeqi NP_146901.2. NC_000854.2.
WP_010865431.1. NC_000854.2.

3D structure databases

ProteinModelPortali Q9YG90.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272557.APE_0011.1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAA78920 ; BAA78920 ; APE_0011.1 .
GeneIDi 1445583.
KEGGi ape:APE_0011.1.

Phylogenomic databases

eggNOGi COG1830.
HOGENOMi HOG000224790.
KOi K11645.
OMAi SRNMVII.

Enzyme and pathway databases

BioCyci APER272557:GJD6-8-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
InterProi IPR013785. Aldolase_TIM.
IPR002915. DeoC/FbaB/lacD_aldolase.
[Graphical view ]
Pfami PF01791. DeoC. 1 hit.
[Graphical view ]
PIRSFi PIRSF038992. Aldolase_Ia. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1.

Entry informationi

Entry nameiALF1_AERPE
AccessioniPrimary (citable) accession number: Q9YG90
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: June 6, 2002
Last modified: October 29, 2014
This is version 75 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3