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Q9YG90 (ALF1_AERPE) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable fructose-bisphosphate aldolase class 1

EC=4.1.2.13
Alternative name(s):
Probable fructose-bisphosphate aldolase class I
Short name=FBP aldolase
Gene names
Name:fba
Ordered Locus Names:APE_0011.1
OrganismAeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) [Complete proteome] [HAMAP]
Taxonomic identifier272557 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiDesulfurococcalesDesulfurococcaceaeAeropyrum

Protein attributes

Sequence length272 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.

Enzyme regulation

Activated by citrate By similarity.

Subunit structure

Homooligomer By similarity.

Subcellular location

Cytoplasm Probable.

Sequence similarities

Belongs to the DeoC/FbaB aldolase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandSchiff base
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionfructose-bisphosphate aldolase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 272272Probable fructose-bisphosphate aldolase class 1
PRO_0000138947

Sites

Active site1841Schiff-base intermediate with dihydroxyacetone-P By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9YG90 [UniParc].

Last modified June 6, 2002. Version 3.
Checksum: D992DAFA81A6ADAF

FASTA27229,583
        10         20         30         40         50         60 
MISSQDVGKR VRLSRILPDG RSVIFAFDHG IEHGPGEIPE ERLDPRLLIR EVVEAGVDAI 

        70         80         90        100        110        120 
MTTPGIARLT WDIWANRVAM IIKVSGKTSI RPQDDQFLQS AISSVDEVVA LGGDGVAATV 

       130        140        150        160        170        180 
YWGSQFEDKM LERWTRIRLR AEKLGLPALQ LAYPRGPHIK NRYAVDIVAY GARAAMETGA 

       190        200        210        220        230        240 
DLIKTYYTGS TESFRRVVSA AGGVPVLMSG GARTPSPQEF LHKVYSVMEA GGGGVVVGRN 

       250        260        270 
IFQAGDIRAM VKAIRAIVHE GFDPEKASKL LG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000002 Genomic DNA. Translation: BAA78920.2.
PIRF72752.
RefSeqNP_146901.2. NC_000854.2.

3D structure databases

ProteinModelPortalQ9YG90.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272557.APE_0011.1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA78920; BAA78920; APE_0011.1.
GeneID1445583.
KEGGape:APE_0011.1.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1830.
HOGENOMHOG000224790.
KOK11645.
OMAVLMQKGM.
ProtClustDBPRK07226.

Enzyme and pathway databases

BioCycAPER272557:GJD6-8-MONOMER.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
InterProIPR013785. Aldolase_TIM.
IPR002915. DeoC/FbaB/lacD_aldolase.
[Graphical view]
PfamPF01791. DeoC. 1 hit.
[Graphical view]
PIRSFPIRSF038992. Aldolase_Ia. 1 hit.
ProtoNetSearch...

Entry information

Entry nameALF1_AERPE
AccessionPrimary (citable) accession number: Q9YG90
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: June 6, 2002
Last modified: October 16, 2013
This is version 71 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families