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Protein

DNA polymerase sliding clamp 1

Gene

pcn1

Organism
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processDNA replication

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymerase sliding clamp 1UniRule annotation
Alternative name(s):
Proliferating cell nuclear antigen homolog 1UniRule annotation
Short name:
PCNA 1UniRule annotation
Gene namesi
Name:pcn1UniRule annotation
Synonyms:pcnA
Ordered Locus Names:APE_0162
OrganismiAeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Taxonomic identifieri272557 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiDesulfurococcalesDesulfurococcaceaeAeropyrum
Proteomesi
  • UP000002518 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001491891 – 247DNA polymerase sliding clamp 1Add BLAST247

Proteomic databases

PRIDEiQ9YFT8

Interactioni

Subunit structurei

Heterotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA (By similarity).By similarity

Protein-protein interaction databases

STRINGi272557.APE_0162

Structurei

3D structure databases

ProteinModelPortaliQ9YFT8
SMRiQ9YFT8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PCNA family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00488 Archaea
COG0592 LUCA
HOGENOMiHOG000222371
KOiK04802
OMAiSDGFDKY
OrthoDBiPOG093Z0814

Family and domain databases

HAMAPiMF_00317 DNApol_clamp_arch, 1 hit
InterProiView protein in InterPro
IPR000730 Pr_cel_nuc_antig
IPR022649 Pr_cel_nuc_antig_C
IPR022659 Pr_cel_nuc_antig_CS
IPR022648 Pr_cel_nuc_antig_N
PANTHERiPTHR11352:SF0 PTHR11352:SF0, 1 hit
PfamiView protein in Pfam
PF02747 PCNA_C, 1 hit
PF00705 PCNA_N, 1 hit
PROSITEiView protein in PROSITE
PS01251 PCNA_1, 1 hit

Sequencei

Sequence statusi: Complete.

Q9YFT8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFRYEAKVFK ELVDSVSKIL DEGLFIITGE GLRLRGMDPA RVALVDIEIP
60 70 80 90 100
SSSFFDFYMA GDVERVELGV NMETLKGVVA RAKKGDQLEV RVREDKVLFI
110 120 130 140 150
VESVVLRRYL LPNLEVIVDV PEDISLEFDA TATVIADVVK KTLRDVELVG
160 170 180 190 200
DIVEFDAGED YLSIRSVGPE RRRVETRLTR ESPALIDLEV KEPATSRYDV
210 220 230 240
GYLKRMLGVA KIAESIELSF STDKPLKMVF KSPDGSRVTY LLAPSTG
Length:247
Mass (Da):27,667
Last modified:February 21, 2001 - v2
Checksum:iDAF4B406FF54EFB1
GO

Sequence cautioni

The sequence BAA79073 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000002 Genomic DNA Translation: BAA79073.1 Different initiation.
PIRiG72771

Genome annotation databases

EnsemblBacteriaiBAA79073; BAA79073; APE_0162
KEGGiape:APE_0162

Similar proteinsi

Entry informationi

Entry nameiPCNA1_AERPE
AccessioniPrimary (citable) accession number: Q9YFT8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: February 21, 2001
Last modified: May 23, 2018
This is version 94 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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