Reviewed, UniProtKB/Swiss-Prot Q9YFA8 (DCD_AERPE)

Names and origin

Protein names

Recommended name:
    Probable deoxycytidine triphosphate deaminase
      Short name=dCTP deaminase
    EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	APE_0333.1

Organism

Aeropyrum pernix [Complete proteome] [HAMAP]

Taxonomic identifier

56636 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Desulfurococcales › Desulfurococcaceae › Aeropyrum

Protein attributes

Sequence length	178 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP protein binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 178	178	Probable deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_0000156026

Sequences

	Sequence		Length	Mass (Da)
	Q9YFA8-1 [UniParc]. Last modified June 26, 2007. Version 2. Checksum: C54A7B095F7C8896	FASTA	178	19,653
	10 20 30 40 50 60 MILSDRDIRA LLAIGDLVVE PLSGDTVREN GLDLRLGRGF CRFKRSDRVL DPRAPGSPGE 70 80 90 100 110 120 FYECGEGDEI IVGPGEHMLL HTQEYIRLPG YVAGLVNLRS TWARTGIYIP ATVVDAGFEG 130 140 150 160 170 QLTIEVVGSG FPVKLYPGDR FLHLVLVKLQ SPAMNPYRGR YQGQRGVRLP KLFAKNTG

References

[1]

"Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon, Aeropyrum pernix K1." Kawarabayasi Y., Hino Y., Horikawa H., Yamazaki S., Haikawa Y., Jin-no K., Takahashi M., Sekine M., Baba S., Ankai A., Kosugi H., Hosoyama A., Fukui S., Nagai Y., Nishijima K., Nakazawa H., Takamiya M., Masuda S. , Funahashi T., Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Kubota K., Nakamura Y., Nomura N., Sako Y., Kikuchi H. DNA Res. 6:83-101(1999) [PubMed: 10382966] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000002 Genomic DNA. Translation: BAA79288.2.
PIR	D72724.
RefSeq	NP_147155.2.
3D structure databases
SMR	Q9YFA8. Positions 1-174.
ModBase	Search...
Genome annotation databases
GeneID	1444552.
GenomeReviews	Gene locus APE_0333.1 in contig BA000002_GR.
KEGG	ape:APE_0333.1.
NMPDR	fig|272557.1.peg.263.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG553199.
Enzyme and pathway databases
BioCyc	APER272557:APE0333-MONOMER.
BRENDA	3.5.4.13. 256344.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. DeoxyUTP_pyroPase_dom. [Graphical view]
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_AERPE

Accession

Primary (citable) accession number: Q9YFA8

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	June 26, 2007
Last modified:	February 9, 2010
This is version 52 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)