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Protein

DNA polymerase sliding clamp 3

Gene

pcn3

Organism
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processDNA replication

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymerase sliding clamp 3UniRule annotation
Alternative name(s):
DNA polymerase sliding clamp B2UniRule annotation
Proliferating cell nuclear antigen homolog 3UniRule annotation
Short name:
PCNA 3UniRule annotation
Gene namesi
Name:pcn3UniRule annotation
Synonyms:pcnB2
Ordered Locus Names:APE_0441.1
OrganismiAeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Taxonomic identifieri272557 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiDesulfurococcalesDesulfurococcaceaeAeropyrum
Proteomesi
  • UP000002518 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001491911 – 249DNA polymerase sliding clamp 3Add BLAST249

Interactioni

Subunit structurei

Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.UniRule annotation

Protein-protein interaction databases

STRINGi272557.APE_0441.1

Structurei

3D structure databases

ProteinModelPortaliQ9YEZ5
SMRiQ9YEZ5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PCNA family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00488 Archaea
COG0592 LUCA
HOGENOMiHOG000222371
KOiK04802
OMAiKCANSDD
OrthoDBiPOG093Z0814

Family and domain databases

HAMAPiMF_00317 DNApol_clamp_arch, 1 hit
InterProiView protein in InterPro
IPR000730 Pr_cel_nuc_antig
IPR022649 Pr_cel_nuc_antig_C
IPR022648 Pr_cel_nuc_antig_N
PANTHERiPTHR11352:SF0 PTHR11352:SF0, 1 hit
PfamiView protein in Pfam
PF02747 PCNA_C, 1 hit
PF00705 PCNA_N, 1 hit
PRINTSiPR00339 PCNACYCLIN

Sequencei

Sequence statusi: Complete.

Q9YEZ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADARFYFSD ARTWRYMVAS IEKIIEEGVF VATGEGLSLR ALDTSHVAMV
60 70 80 90 100
DLYYPNTAFI EYDIGGESVE FGVSFDLLSK VLRRARKEDE LVLEVEGSRL
110 120 130 140 150
AVKLKSRGER TFRIPQVVMT YEKLPEPKVS FTVRARMLGS TFREAVRDLE
160 170 180 190 200
PHSETLTLRA LEDALLLVGS SEMATVEIEL SQSRGSLLDY EAESQDRASY
210 220 230 240
SIEYFSEMLS AAQAADAVVV SFSEDAPVRV DMEYLGGGRL TFYVSPKIE
Length:249
Mass (Da):27,935
Last modified:February 21, 2001 - v2
Checksum:iE84D470C59FA8EDF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000002 Genomic DNA Translation: BAA79401.2
PIRiE72738

Genome annotation databases

EnsemblBacteriaiBAA79401; BAA79401; APE_0441.1
KEGGiape:APE_0441.1

Similar proteinsi

Entry informationi

Entry nameiPCNA3_AERPE
AccessioniPrimary (citable) accession number: Q9YEZ5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: February 21, 2001
Last modified: March 28, 2018
This is version 93 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health